Role of anion-cation interactions on the pre-steady-state currents of the rat Na+-Cl--dependent GABA cotransporter rGAT1

Journal of Physiology

Volumn 541, Issue 2, 2002, Pages 343-350

  Bossi, Elena ^a   Giovannardi, Stefano ^a   Binda, Francesca ^a   Forlani, Greta ^a   Peres, Antonio ^a  

^a UNIVERSITY OF INSUBRIA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

4 AMINOBUTYRIC ACID; ACETIC ACID; ANION; CALCIUM; CARRIER PROTEIN; CATION; CHLORIDE; RGAT1 PROTEIN; SODIUM; TETRAMETHYLAMMONIUM; UNCLASSIFIED DRUG; 4 AMINOBUTYRIC ACID CARRIER; RGAT1;

AMINO ACID TRANSPORT; ANALYTIC METHOD; ANIMAL CELL; ARTICLE; CONTROLLED STUDY; EXTRACELLULAR CALCIUM; ION CURRENT; ION TRANSPORT; MOLECULAR INTERACTION; NONHUMAN; OOCYTE; PRIORITY JOURNAL; QUALITATIVE ANALYSIS; RAT; STEADY STATE; VOLTAGE CLAMP; CHEMICAL PHENOMENA; HETEROLOGOUS EXPRESSION; MEMBRANE CURRENT; PRE STEADY STATE CURRENT; RATE CONSTANT; VOLTAGE CLAMP TECHNIQUE;

ALGORITHMS; ANIMALS; CALCIUM; CARRIER PROTEINS; CHLORIDES; ELECTROPHYSIOLOGY; GABA PLASMA MEMBRANE TRANSPORT PROTEINS; GAMMA-AMINOBUTYRIC ACID; MEMBRANE POTENTIALS; MEMBRANE PROTEINS; MEMBRANE TRANSPORT PROTEINS; OOCYTES; ORGANIC ANION TRANSPORTERS; PATCH-CLAMP TECHNIQUES; RATS; RNA; SODIUM; SODIUM CHANNELS; XENOPUS LAEVIS;

EID: 0036623966     PISSN: 00223751     EISSN: None     Source Type: Journal    
DOI: 10.1113/jphysiol.2001.013457     Document Type: Article

References (25)

1. ARMSTRONG, C. M. & COTA, G. (1990). Modification of sodium channel gating by lanthanum. Some effect that cannot be explained by surface charge theory. Journal of General Physiology 96, 1129-1140.
2. ARRIZA, J. L., ELIASOF, S., KAVANAUGH, M. P. & AMARA, S. G. (1997). Excitatory amino acid transporter 5, a retinal glutamate transporter coupled to a chloride conductance. Proceedings of the National Academy of Sciences of the USA 94, 4155-4160.
3. BENNETT, E., URCAN, M. S., TINKLE, S. S., KOSZOWSKI, A. G. & LEVINSON, S. R. (1997). Contribution of sialic acid to the voltage dependence of sodium channel gating. A possible electrostatic mechanism. Journal of General Physiology 109, 327-343.
4. +/phosphate cotransporter. Journal of Bioenergetics and Biomembranes 30, 187-194.
5. BINDA, F., BOSSI, E., GIOVANNARDI, S., FORLANI, G. & PERES, A. (2002). Temperature effects on the presteady-state and transport-associated currents of GABA cotransporter rGAT1. FEBS Letters 512, 303-307.
6. BOSSI, E., CENTINAIO, E., CASTAGNA, M., GIOVANNARDI, S., VINCENTI, S., SACCHI, V. F. & PERES, A. (1999). Ion binding and permeation through the lepidopteran amino acid transporter KAAT1 expressed in Xenopus oocytes. Journal of Physiology 515, 729-742.
7. CASTAGNA, M., SHAYAKUL, C., TROTTI, D., SACCHI, V. F., HARVEY, W. R. & HEDIGER, M. A. (1998). Cloning and characterization of a potassium-coupled amino acid transporter. Proceedings of the National Academy of Sciences of the USA 95, 5395-5400.
8. FORLANI, G., BOSSI, E., GHIRARDELLI, R., GIOVANNARDI, S., BINDA, F., BONADIMAN, L., IELMINI, L. & PERES, A. (2001). Mutation K448E in the external loop 5 of rat GABA transporter rGAT1 induces pH sensitivity and alters substrate interactions. Journal of Physiology 536, 479-494.
9. +-coupled phosphate cotransporter kinetics. Biophysical Journal 79, 215-230.
10. FRANKENHAEUSER, B. & HODGKIN, A. L. (1957). The action of calcium on the electrical properties of squid axons. Journal of Physiology 137, 218-244.
11. GUASTELLA, J., NELSON, N., NELSON, H., CZYZYC, L., KEYNAN, S., MIEDEL, M. C., DAVIDSON, N., LESTER, H. A. & KANNER, B. I. (1990). Cloning and expression of a rat brain GABA transporter. Science 249, 1303-1306.
12. +/glucose cotransporter (SGLT1). Journal of Membrane Biology 155, 175-186.
13. +/glucose cotransporter. Nature 330, 379-381.
14. HILLE, B. (1992). Ionic Channels of Excitable Membranes, 2nd edn. Sinauer Associates, USA.
15. HILLE, B., WOODHALL, A. M. & SHAPIRO, B. I. (1975). Negative surface charge near sodium channel of nerve: divalent ions, monovalent ions and pH. Philosophical Transactions of the Royal Society B 270, 301-318.
16. +-coupled cotransporters GAT1 and SGLT1. Journal of Biological Chemistry 275, 37414-37422.
17. -). cotransport function. Kinetic studies in giant Xenopus oocyte membrane patches. Journal of General Physiology 114, 445-457.
18. LU, C.-C., KABAKOV, A., MARKIN, V. S., MAGER, S., FRAZIER, G. A. & HILGEMANN, D. W. (1995). Membrane transport mechanisms probed by capacitance measurements with megahertz voltage clamp. Proceedings of the National Academy of Sciences of the USA 92, 11220-11224.
19. MAGER, S., KLEINBERGER-DORON, N., KESHET, G. I., DAVIDSON, N., KANNER, B.I. & LESTER, H. A. (1996). Ion binding and permeation at the GABA transporter GAT1. Journal of Neuroscience 165 5405-5414.
20. MAGER, S., NAEVE, J., QUICK, M., LABARCA, C., DAVIDSON, N. & LESTER, H. A. (1993). Steady states, charge movements, and rates for a cloned GABA transporter expressed in Xenopus oocytes. Neuron 10, 177-188.
21. NOWAK, M. W., GALLIVAN, J. P., SILVERMAN, S. K., LABARCA, C. G., DOUGHERTY, D. A. & LESTER, H. A. (1998). In vivo incorporation of unnatural amino acids into ion channels in Xenopus oocyte expression system. Methods in Enzymology 293, 504-529.
22. PALACÍN, M., ESTÉVEZ, R., BERTRAN, J. & ZORZANO, A. (1998). Molecular biology of mammalian plasma membrane amino acid transporters. Physiological Reviews 78, 969-1054.
23. +/glucose transporter: I. Voltage-clamp studies. Journal of Membrane Biology 125, 49-62.
24. +/glucose cotransporter: II. A transport model under nonrapid equilibrium conditions. Journal of Membrane Biology 125, 63-79.
25. - -dependent betaine transporter that is regulated by hypertonicity. Journal of Biological Chemistry 267, 649-652.