Assessing exercise capacity, quality of life and haemodynamics in heart failure: Do the tests tell us the same thing?

European Journal of Heart Failure

Volumn 4, Issue 3, 2002, Pages 289-295

  Houghton, Andrew R ^a   Harrison, Maxine ^a   Cowley, Alan J ^a   Hampton, John R ^a  

^a NOTTINGHAM UNIVERSITY HOSPITALS NHS TRUST   (United Kingdom)

Author keywords

Exercise capacity; Haemodynamics; Heart failure; Quality of life

Indexed keywords

ADULT; AGED; ARTICLE; CLINICAL ARTICLE; CORRELATION ANALYSIS; DIAGNOSTIC ERROR; DRUG EFFICACY; EXERCISE; FEMALE; HEART FAILURE; HEART INDEX; HEART OUTPUT; HEMODYNAMICS; HUMAN; LIMB BLOOD FLOW; MALE; PRIORITY JOURNAL; QUALITY OF LIFE; SCORING SYSTEM; TREADMILL EXERCISE;

AGED; AGED, 80 AND OVER; EXERCISE TEST; EXERCISE TOLERANCE; FEMALE; HEART FAILURE, CONGESTIVE; HEMODYNAMIC PROCESSES; HUMANS; MALE; MIDDLE AGED; PREDICTIVE VALUE OF TESTS; QUALITY OF LIFE; QUESTIONNAIRES; STATISTICS, NONPARAMETRIC;

EID: 0036623853     PISSN: 13889842     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1388-9842(01)00236-7     Document Type: Article

References (22)

1. Narang R, Swedberg K, Cleland JGF. What is the ideal study design for evaluation of treatment for heart failure? Insights from trials assessing the effect of ACE inhibitors on exercise capacity. Eur Heart J 1996;17:120-34.
2. Cowley AJ, Fullwood L, Stainer K, et al. Exercise tolerance in patients with heart failure - how should it be measured? Eur Heart J 1991;12:50-4.
3. Francis GS, Rector TS. Maximal exercise tolerance as a therapeutic end point in heart failure - are we relying on the right measure? Am J Cardiol 1994;73:304-6.
4. Bittner V, Weiner DH, Yusuf S, et al. Prediction of mortality and morbidity with a 6-minute walk test in patients with left ventricular dysfunction. J Am Med Assoc 1993;270:1702-7.
5. O'Keeffe ST, Lye M, Donnellan C, et al. Reproducibility and responsiveness of quality of life assessment and six minute walk test in elderly heart failure patients. Heart 1998:80:377-82.
6. Cowley AJ, Stainer K, Wynne RD, et al. Symptomatic assessment of patients with heart failure: double-blind comparison of increasing doses of diuretics and captopril in moderate heart failure. Lancet 1986;2:770-2.
7. Walsh JT, Charlesworth A, Andrews R, et al. Relation of daily activity levels in patients with chronic heart failure to long-term prognosis. Am J Cardiol 1997;79:1364-9.
8. Bassey EJ, Dallosso HM, Fentam PH, et al. Validation of a simple mechanical accelerometer (pedometer) for the estimation of walking activity. Eur J Appl Physiol 1987;56:323-30.
9. Walsh JT, Andrews R, Evans A, et al. Failure of 'effective' treatment for heart failure to improve normal customary activity. Br Heart J 1995;74:373-6.
10. Cowley AJ, Stainer K, Murphy DT, et al. A non invasive method for measuring cardiac output: the effect of a Christmas lunch. Lancet 1986;2:1422-4.
11. Whitney RJ. The measurement of volume changes in human limbs. J Physiol 1953;121:1-27.
12. Muller AF. Studies of central and regional haemodynamic parameters in chronic heart failure. DM Thesis. UK: University of Nottingham, 1992.
13. Cowley AJ, Skene AM. Treatment of severe heart failure: quantity of quality of life? A trial of enoximone. Br Heart J 1994;72:226-30.
14. Hampton JR, van Veldhuisen DJ, Kleber FX, et al. Randomised study of effect of ibopamine on survival in patients with advanced severe heart failure. Lancet 1997;349:971-7.
15. Staniforth AD, Andrews R, Harrison M, et al. Value of improved treadmill exercise capacity: lessons from a study of rate responsive pacing. Heart 1998;80:383-6.
16. Rector TS, Johnson GR, Dunkman WB, et al. Evaluation by patients with heart failure of the effects of enalapril compared with hydralazine plus isosorbide dinitrate on quality of life. V-HeFT II. Circulation 1993;87(Suppl VI):VI-71-VI-77.
17. Franciosa JA, Park M, Levine TB. Lack of correlation between exercise capacity and indexes of resting left ventricular performance in heart failure. Am J Cardiol 1981;47:33-9.
18. Franciosa JA, Goldsmith SR, Cohn JN. Contrasting immediate and long-term effects of isosorbide dinitrate on exercise capacity in congestive heart failure. Am J Med 1980;69:559-66.
19. Cowley AJ, Fullwood LJ, Muller AF, et al. Exercise capability in heart failure: is cardiac output important after all? Lancet 1991;337:771-3.
20. Cohn JN, Johnson GR, Shabetai R, et al. for the V-HeFT VA Cooperative Studies Group. Ejection fraction, peak exercise oxygen consumption, cardiothoracic ratio, ventricular arrhythmias, and plasma norepinephrine as determinants of prognosis in heart failure. Circulation 1993;87(Suppl VI):VI-5-VI-16.
21. Muller AF, Batin P, Evans S, et al. Regional blood flow in chronic heart failure: the reason for the lack of correlation between patients' exercise tolerance and cardiac output? Br Heart J 1992;67:478-81.
22. Bassey EJ, Bendall MJ, Pearson M. Muscle strength in the triceps surae and objectively measured walking activity in men and women over 65 years of age. Clin Sci 1988;74:85-9.