메뉴 건너뛰기




Volumn 13, Issue 4, 2002, Pages 243-248

Differential efficacy of different platelet glycoprotein iib/iiia antagonists on platelet/fibrin-mediated clot dynamics under different conditions using thrombelastography: The critical need for anticoagulant

Author keywords

Abciximab; Aggrastat; Calcium; Clot strength and retraction; Contact activation inhibitor; Integrilin; Orbofiban; Platelet aggregation; Platelet glycoprotein IIb IIIa antagonists; Roxifiban; Sibrafiban; Thrombelastography; Tissue factor

Indexed keywords

3 [[3 [4 (AMINOIMINOMETHYL)PHENYL] 4,5 DIHYDRO 5 ISOXAZOLYL]ACETAMIDO] N [(3,5 DIMETHYL 4 ISOXAZOLYL)SULFONYL]ALANINE; [[[3 [4 (AMINOIMINOMETHYL)PHENYL] 4,5 DIHYDRO 5 ISOXAZOLYL]ACETYL]AMINO] N [(3 METHYLPHENYL)SULFONYL]ALANINE; ABCIXIMAB; CALCIUM; EPTIFIBATIDE; FIBRINOGEN RECEPTOR ANTAGONIST; HEPARIN; LOTRAFIBAN; ORBOFIBAN; ROXIFIBAN; SIBRAFIBAN; THROMBOPLASTIN; TIROFIBAN; UNCLASSIFIED DRUG;

EID: 0036620763     PISSN: 09546928     EISSN: None     Source Type: Journal    
DOI: 10.1097/00019501-200206000-00007     Document Type: Article
Times cited : (2)

References (29)
  • 1
    • 0021861117 scopus 로고
    • Role of platelets and thrombosis in coronary atherosclerotic disease and sudden death
    • Fuster V, Steele PM, Chesebro JH. Role of platelets and thrombosis in coronary atherosclerotic disease and sudden death. J Am Coll Cardiol 1985; 5:175B-184B.
    • (1985) J Am Coll Cardiol , vol.5
    • Fuster, V.1    Steele, P.M.2    Chesebro, J.H.3
  • 3
    • 0024344935 scopus 로고
    • Specific platelet mediators and unstable coronary artery lesions. Experimental evidence and potential clinical implications
    • Willerson JT, Golino P, Eidt J, Campbell WB, Buja LM. Specific platelet mediators and unstable coronary artery lesions. Experimental evidence and potential clinical implications. Circulation 1989; 21:198-205.
    • (1989) Circulation , vol.21 , pp. 198-205
    • Willerson, J.T.1    Golino, P.2    Eidt, J.3    Campbell, W.B.4    Buja, L.M.5
  • 4
    • 0022502048 scopus 로고
    • Platelet membrane glycoprotein IIb/IIIa: Member of a family of RGD specific adhesion receptors
    • Pytela R, Pierschbacher MS, Ginsberg MH, Plow EF, Ruoslahti E. Platelet membrane glycoprotein IIb/IIIa: member of a family of RGD specific adhesion receptors. Science 1986; 231:1559-1562.
    • (1986) Science , vol.231 , pp. 1559-1562
    • Pytela, R.1    Pierschbacher, M.S.2    Ginsberg, M.H.3    Plow, E.F.4    Ruoslahti, E.5
  • 5
    • 0028345255 scopus 로고
    • Randomized trial of coronary intervention with antibody against platelet GPIIb/IIIa integrin for reduction of clinical restenosis: Results at six months
    • Topol EJ, Califf RM, Weisman HF, Ellis SG, Tcheng JE, Worley S, et al. (EPIC Investigators). Randomized trial of coronary intervention with antibody against platelet GPIIb/IIIa integrin for reduction of clinical restenosis: results at six months Lancet 1994; 343:881-886.
    • (1994) Lancet , vol.343 , pp. 881-886
    • Topol, E.J.1    Califf, R.M.2    Weisman, H.F.3    Ellis, S.G.4    Tcheng, J.E.5    Worley, S.6
  • 6
    • 2642599026 scopus 로고    scopus 로고
    • Inhibition of the platelet glycoprotein IIb/IIIa receptor with tirofiban in unstable angina and non-Q-wave myocardial infarction. Platelet receptor inhibition in ischemic syndrome management in patients limited by unstable signs and symptoms
    • PRISM-PLUS Study Investigators Inhibition of the platelet glycoprotein IIb/IIIa receptor with tirofiban in unstable angina and non-Q-wave myocardial infarction. Platelet receptor inhibition in ischemic syndrome management in patients limited by unstable signs and symptoms. N Engl J Med 1998; 338:1488-1497.
    • (1998) N Engl J Med , vol.338 , pp. 1488-1497
  • 7
    • 0028930680 scopus 로고
    • Multicenter, randomized, double-blind, placebo-controlled trial of the platelet integrin glycoprotein IIb/IIIa blocker, Integrilin in elective coronary intervention
    • Tcheng JE, Harrington RA, Kottke-Marchant K, Kleiman NS, Ellis SG, Kereiakes DJ, et al. (IMPACT Investigators). Multicenter, randomized, double-blind, placebo-controlled trial of the platelet integrin glycoprotein IIb/IIIa blocker, Integrilin in elective coronary intervention. Circulation 1995; 91:2151-2157.
    • (1995) Circulation , vol.91 , pp. 2151-2157
    • Tcheng, J.E.1    Harrington, R.A.2    Kottke-Marchant, K.3    Kleiman, N.S.4    Ellis, S.G.5    Kereiakes, D.J.6
  • 8
    • 0027194452 scopus 로고
    • Profound inhibition of platelet aggregation with monoclonal antibody c7E3 after thrombolytic therapy: Results of the thrombolysis and angioplasty in myocardial infarction (TAMI) 8 pilot study
    • Kleiman NS, Ohman EM, Califf RM, George BS, Kereiakes D, Aguirre FV, et al. Profound inhibition of platelet aggregation with monoclonal antibody c7E3 after thrombolytic therapy: results of the thrombolysis and angioplasty in myocardial infarction (TAMI) 8 pilot study. J Am Coll Cardiol 1993; 22:381-389.
    • (1993) J Am Coll Cardiol , vol.22 , pp. 381-389
    • Kleiman, N.S.1    Ohman, E.M.2    Califf, R.M.3    George, B.S.4    Kereiakes, D.5    Aguirre, F.V.6
  • 9
    • 0020312395 scopus 로고
    • Ultrastructure of clots during isometric contraction
    • Cohen K, Gerrard JM, White JG. Ultrastructure of clots during isometric contraction. J Cell Biol 1982; 93:775-483.
    • (1982) J Cell Biol , vol.93 , pp. 775-483
    • Cohen, K.1    Gerrard, J.M.2    White, J.G.3
  • 10
    • 0027979422 scopus 로고
    • Uncoupling fibrin from integrin receptors hastens fibrinolysis at the platelet-fibrin interface
    • Brastn JV, Jerome WG, Hantgan RR. Uncoupling fibrin from integrin receptors hastens fibrinolysis at the platelet-fibrin interface. Blood 1994; 83:982-990.
    • (1994) Blood , vol.83 , pp. 982-990
    • Brasten, J.V.1    Jerome, W.G.2    Hantgan, R.R.3
  • 11
    • 0021868360 scopus 로고
    • Platelets interact with fibrin only after activation
    • Hantgan RR, Taylor RG, Lewis JC. Platelets interact with fibrin only after activation. Blood 1985; 65:1299-1308.
    • (1985) Blood , vol.65 , pp. 1299-1308
    • Hantgan, R.R.1    Taylor, R.G.2    Lewis, J.C.3
  • 12
    • 0000444685 scopus 로고
    • Quantitative clot retraction: A method assessing the function of fresh and stored platelets and GPIIb/IIIa receptors
    • Reid TJ, Greilich PE, Carr ME, Alving BM. Quantitative clot retraction: a method assessing the function of fresh and stored platelets and GPIIb/IIIa receptors. Blood 1994; 84:1839-1847.
    • (1994) Blood , vol.84 , pp. 1839-1847
    • Reid, T.J.1    Greilich, P.E.2    Carr, M.E.3    Alving, B.M.4
  • 13
    • 8044235823 scopus 로고    scopus 로고
    • Novel nonpeptide antiplatelet GPIIb/IIIa receptor antagonist, DMP754: Receptor binding affinity and specificity
    • Mousa SA, Forsythe M, Lorelli W, Bozarth J, Xue C-B, Wityak J, et al. Novel nonpeptide antiplatelet GPIIb/IIIa receptor antagonist, DMP754: receptor binding affinity and specificity. Coron Artery Dis 1996; 7:767-774.
    • (1996) Coron Artery Dis , vol.7 , pp. 767-774
    • Mousa, S.A.1    Forsythe, M.2    Lorelli, W.3    Bozarth, J.4    Xue, C.-B.5    Wityak, J.6
  • 14
    • 0034127789 scopus 로고    scopus 로고
    • Comparative in vitro efficacy of different platelet glycoprotein IIb/IIIa antagonists on platelet-mediated clot strength induced by tissue factor with use of thromboelastography: Differentiation among glycoprotein IIb/IIIa antagonists
    • Mousa SA, Khurana S, Forsythe MS. Comparative in vitro efficacy of different platelet glycoprotein IIb/IIIa antagonists on platelet-mediated clot strength induced by tissue factor with use of thromboelastography: differentiation among glycoprotein IIb/IIIa antagonists. Arterioscler Thromb Vasc Biol 2000; 20:1162-1167.
    • (2000) Arterioscler Thromb Vasc Biol , vol.20 , pp. 1162-1167
    • Mousa, S.A.1    Khurana, S.2    Forsythe, M.S.3
  • 15
    • 0032520709 scopus 로고    scopus 로고
    • Inhibition of platelet-mediated clot retraction by integrin antagonist
    • Hantgan RR, Mousa SA. Inhibition of platelet-mediated clot retraction by integrin antagonist. Thromb Res 1998; 89:271-279.
    • (1998) Thromb Res , vol.89 , pp. 271-279
    • Hantgan, R.R.1    Mousa, S.A.2
  • 16
    • 0001495969 scopus 로고
    • Blutgerinnungstudien mit der thromboelastograpie, einem ueuen untersuchungsverfahren
    • Hartert H. Blutgerinnungstudien mit der Thromboelastograpie, einem ueuen Untersuchungsverfahren. Klin Wochenschrift 1948; 26:577-583.
    • (1948) Klin Wochenschrift , vol.26 , pp. 577-583
    • Hartert, H.1
  • 17
    • 0027202435 scopus 로고
    • Comparison of thromboelastography to bleeding time and standard coagulation tests in patients after cardiopulmonary bypass
    • Essel JH, Martin TJ, Salinas J, Thompson JM, Smith VC. Comparison of thromboelastography to bleeding time and standard coagulation tests in patients after cardiopulmonary bypass. J Cardiovasc Anesth 1993; 7:410-415.
    • (1993) J Cardiovasc Anesth , vol.7 , pp. 410-415
    • Essel, J.H.1    Martin, T.J.2    Salinas, J.3    Thompson, J.M.4    Smith, V.C.5
  • 18
    • 0016827604 scopus 로고
    • Studies of fibrinolytic and coagulation factors during open heart surgery. II. Postoperative tendency and changes in the coagulation system
    • Muller N, Popov-Cenic S, Buttner W, Kladetzky RG, Egil H. Studies of fibrinolytic and coagulation factors during open heart surgery. II. Postoperative tendency and changes in the coagulation system. Thromb Res 1975; 7:589-598.
    • (1975) Thromb Res , vol.7 , pp. 589-598
    • Muller, N.1    Popov-Cenic, S.2    Buttner, W.3    Kladetzky, R.G.4    Egil, H.5
  • 20
    • 0028953273 scopus 로고
    • Changes in transfusion therapy and re-exploration rate after institution of a blood management program in cardiac surgical patients
    • Spiess BD, Gillies BS, Chandler W, Verrier E. Changes in transfusion therapy and re-exploration rate after institution of a blood management program in cardiac surgical patients. J Cardiothorac Vasc Anesth 1995; 9:168-173.
    • (1995) J Cardiothorac Vasc Anesth , vol.9 , pp. 168-173
    • Spiess, B.D.1    Gillies, B.S.2    Chandler, W.3    Verrier, E.4
  • 21
    • 0030754004 scopus 로고    scopus 로고
    • First chronic platelet glycoprotein IIb/IIIa integrin blockade: A randomized, placebo-controlled pilot study of Xemilofiban in unstable angina with percutaneous coronary interventions
    • Simpfendorfer C, Kottke-Marchant K, Lowrie M, Anders RJ, Burns DM, Miller DP, et al. First chronic platelet glycoprotein IIb/IIIa integrin blockade: a randomized, placebo-controlled pilot study of Xemilofiban in unstable angina with percutaneous coronary interventions. Circulation 1997; 96:76-81.
    • (1997) Circulation , vol.96 , pp. 76-81
    • Simpfendorfer, C.1    Kottke-Marchant, K.2    Lowrie, M.3    Anders, R.J.4    Burns, D.M.5    Miller, D.P.6
  • 22
    • 0342872079 scopus 로고    scopus 로고
    • Profound and sustained inhibition of platelet aggregation by Fradafiban, nonpeptide platelet glycoprotein IIb/IIIa antagonist, and its orally active prodrug, Lefradafiban, in men
    • Muller TH, Weisenberger H, Brickl R, Narjes H, Himmelsbach F. Profound and sustained inhibition of platelet aggregation by Fradafiban, nonpeptide platelet glycoprotein IIb/IIIa antagonist, and its orally active prodrug, Lefradafiban, in men. Circulation 1997; 96:1130-1138.
    • (1997) Circulation , vol.96 , pp. 1130-1138
    • Muller, T.H.1    Weisenberger, H.2    Brickl, R.3    Narjes, H.4    Himmelsbach, F.5
  • 23
    • 0032477680 scopus 로고    scopus 로고
    • Randomized trial of an oral platelet glycoprotein IIb/IIIa antagonist, sibrafiban, in patients after an acute coronary syndrome: Results of the TIMI 12 trial. Thrombolysis in myocardial infarction
    • Cannon CP, McCabe CH, Borzak S, Henry TD, Tischler MD, Mueller HS, et al. Randomized trial of an oral platelet glycoprotein IIb/IIIa antagonist, sibrafiban, in patients after an acute coronary syndrome: results of the TIMI 12 trial. Thrombolysis in myocardial infarction. Circulation 1998; 97:340-349.
    • (1998) Circulation , vol.97 , pp. 340-349
    • Cannon, C.P.1    McCabe, C.H.2    Borzak, S.3    Henry, T.D.4    Tischler, M.D.5    Mueller, H.S.6
  • 24
    • 0001790858 scopus 로고    scopus 로고
    • Dose-finding and tolerability of a new oral platelet GPIIb/IIIa inhibitor, SB 214857, in patients with coronary artery and cerebrovascular disease: The APLAUD results
    • Harrington RA, Graffagnino C, Armstrong PW, Joseph D, Card TL, Sigmon KN, et al. Dose-finding and tolerability of a new oral platelet GPIIb/IIIa inhibitor, SB 214857, in patients with coronary artery and cerebrovascular disease: The APLAUD results. Circulation 1998; 98(suppl 17):1 1303.
    • (1998) Circulation , vol.98 , Issue.SUPPL. 17
    • Harrington, R.A.1    Graffagnino, C.2    Armstrong, P.W.3    Joseph, D.4    Card, T.L.5    Sigmon, K.N.6
  • 25
    • 0001427937 scopus 로고    scopus 로고
    • Novel antiplatelet therapies: Recent advances in the development of platelet gpiib/iiia receptor antagonists
    • Serruys PW, Holmes D, editors. Philadelphia: Current Medicine
    • Mousa SA, Topol EJ. Novel antiplatelet therapies: recent advances in the development of platelet gpiib/iiia receptor antagonists. In: Serruys PW, Holmes D, editors: Current review of interventional cardiology. 3rd ed. Philadelphia: Current Medicine; 1997. Vol. 13, pp. 114-129.
    • (1997) Current review of interventional cardiology. 3rd ed. , vol.13 , pp. 114-129
    • Mousa, S.A.1    Topol, E.J.2
  • 26
    • 0032160611 scopus 로고    scopus 로고
    • Discovery of novel orally active non-peptide platelet GPIIb/IIIa receptor antagonist, DMP754: Comparative platelet binding profiles with c7E3
    • Mousa SA, Bozarth J, Lorelli W, Forsythe M, Thoolen M, Slee A, et al. Discovery of novel orally active non-peptide platelet GPIIb/IIIa receptor antagonist, DMP754: comparative platelet binding profiles with c7E3. J Pharmacol Exp Ther 1998; 286:1277-1284.
    • (1998) J Pharmacol Exp Ther , vol.286 , pp. 1277-1284
    • Mousa, S.A.1    Bozarth, J.2    Lorelli, W.3    Forsythe, M.4    Thoolen, M.5    Slee, A.6
  • 27
    • 0031856736 scopus 로고    scopus 로고
    • Orally active Isoxazoline GPIIb/IIIa antagonists
    • Mousa SA, Wityak J. Orally active Isoxazoline GPIIb/IIIa antagonists. Cardiovasc Drug Rev 1998; 16:48-61.
    • (1998) Cardiovasc Drug Rev , vol.16 , pp. 48-61
    • Mousa, S.A.1    Wityak, J.2
  • 28
    • 17944393494 scopus 로고    scopus 로고
    • Oral glycoprotein IIb/IIIa inhibition in patients with unstable coronary syndromes (OPUS-TIMI 16) trial
    • Cannon CP, McCabe CH, Wilcox RG, Langer A, Caspi A, Berink P, et al. Oral glycoprotein IIb/IIIa inhibition in patients with unstable coronary syndromes (OPUS-TIMI 16) trial. Circulation 2000; 102:149-156.
    • (2000) Circulation , vol.102 , pp. 149-156
    • Cannon, C.P.1    McCabe, C.H.2    Wilcox, R.G.3    Langer, A.4    Caspi, A.5    Berink, P.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.