CASK Participates in Alternative Tripartite Complexes in which Mint 1 Competes for Binding with Caskin 1, a Novel CASK-Binding Protein

Journal of Neuroscience

Volumn 22, Issue 11, 2002, Pages 4264-4273

  Tabuchi, Katsuhiko ^a   Biederer, Thomas ^a   Butz, Stefan ^a,b   Südhof, Thomas C ^a  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^b UNIVERSITY OF MÜNSTER   (Germany)

Author keywords

CASK; Caskin; Lin 2; Mint 1; Neurexin; Scaffold; Synapse; Syndecan; Velis

Indexed keywords

ADAPTOR PROTEIN; ANKYRIN; BINDING PROTEIN; CASK PROTEIN; CASKIN 1; CASKIN 2; CELL SURFACE PROTEIN; ISOPROTEIN; NEUREXIN; PROTEIN MINT 1; UNCLASSIFIED DRUG; APBA1 PROTEIN, HUMAN; APBA1 PROTEIN, MOUSE; APBA1 PROTEIN, RAT; CALMODULIN DEPENDENT SERINE KINASE; CALMODULIN-DEPENDENT SERINE KINASE; CARRIER PROTEIN; CASKIN 1 PROTEIN, RAT; CASKIN 2 PROTEIN, RAT; CASKIN2 PROTEIN, HUMAN; CASKIN2 PROTEIN, MOUSE; HYBRID PROTEIN; MEMBRANE PROTEIN; NERVE PROTEIN; NUCLEOSIDE MONOPHOSPHATE KINASE; PROTEIN KINASE (CALCIUM,CALMODULIN); RNA; SIGNAL TRANSDUCING ADAPTOR PROTEIN;

AFFINITY CHROMATOGRAPHY; AMINO ACID SEQUENCE; ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; BRAIN; CAENORHABDITIS ELEGANS; CARBOXY TERMINAL SEQUENCE; CELL WALL; CONTROLLED STUDY; CYTOPLASM; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; MOLECULAR DYNAMICS; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN IMMOBILIZATION; PROTEIN MOTIF; PROTEIN PROTEIN INTERACTION; RAT; SEQUENCE HOMOLOGY; SIGNAL TRANSDUCTION; ANIMAL; ANTIBODY SPECIFICITY; BINDING COMPETITION; BINDING SITE; BIOSYNTHESIS; GENETICS; IMMUNOHISTOCHEMISTRY; MACROMOLECULE; METABOLISM; MOLECULAR CLONING; MOLECULAR GENETICS; MOUSE; PHYSIOLOGY; PROTEIN TERTIARY STRUCTURE; SERODIAGNOSIS;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; BINDING SITES; BINDING, COMPETITIVE; CA(2+)-CALMODULIN DEPENDENT PROTEIN KINASE; CARRIER PROTEINS; CLONING, MOLECULAR; HUMANS; IMMUNOHISTOCHEMISTRY; MACROMOLECULAR SUBSTANCES; MEMBRANE PROTEINS; MICE; MOLECULAR SEQUENCE DATA; NERVE TISSUE PROTEINS; NUCLEOSIDE-PHOSPHATE KINASE; ORGAN SPECIFICITY; PRECIPITIN TESTS; PROTEIN BINDING; PROTEIN ISOFORMS; PROTEIN STRUCTURE, TERTIARY; RATS; RECOMBINANT FUSION PROTEINS; RNA; SEQUENCE HOMOLOGY, AMINO ACID;

EID: 0036617907     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.22-11-04264.2002     Document Type: Article

References (31)

1. Biederer T, Südhof TC (2000) Mints as adaptors: direct binding to neurexins and recruitment of munc18. J Biol Chem 275:39803-39806.
2. Biederer T, Südhof TC (2001) Cask and protein 4.1 support F-actin nucleation on neurexins. J Biol Chem 276:47869-47876.
3. Borg JP, Yang Y, De Taddeo-Borg M, Margolis B, Turner RS (1998a) The X11alpha protein slows cellular amyloid precursor protein processing and reduces Abeta40 and Abeta42 secretion. J Biol Chem 273:14761-14766.
4. Borg JP, Straight SW, Kaech SM, de Taddeo-Borg M, Kroon DE, Karnak D, Turner RS, Kim SK, Margolis B (1998b) Identification of an evolutionarily conserved heterotrimeric protein complex involved in protein targeting. J Biol Chem 273:31633-31636.
5. Butz S, Okamoto M, Südhof TC (1998) A tripartite protein complex with the potential to couple synaptic vesicle exocytosis to cell adhesion in brain. Cell 94:773-782.
6. Cohen AR, Woods DF, Marfatia SM, Walther Z, Chishti AH, Anderson JM, Wood DF (1998) Human CASK/LIN-2 binds syndecan-2 and protein 4.1 and localizes to the basolateral membrane of epithelial cells. J Cell Biol 142:129-138.
7. Dimitratos SD, Woods DF, Bryant PJ (1997) Camguk, Lin-2, and CASK: novel membrane-associated guanylate kinase homologs that also contain CaM kinase domains. Mech Dev 63:127-130.
8. Garner CC, Kindler S, Gundelfinger ED (2000) Molecular determinants of presynaptic active zones. Curr Opin Neurobiol 10:321-327.
9. Guan KL, Dixon JE (1991) Eukaryotic proteins expressed in Escherichia coli: an improved thrombin cleavage and purification procedure of fusion proteins with glutathione S-transferase. Anal Biochem 192:262-267.
10. Hata Y, Slaughter CA, Südhof TC (1993) Synaptic vesicle fusion complex contains unc-18 homologue bound to syntaxin. Nature 366: 347-351.
11. Hata Y, Butz S, Südhof TC (1996) CASK: a novel dlg/PSD95 homologue with an N-terminal calmodulin-dependent protein kinase domain identified by interaction with neurexins. J Neurosci 16:2488-2494.
12. Hoskins R, Hajnal AF, Harp SA, Kim SK (1996) The C. elegans vulval induction gene lin-2 encodes a member of the MAGUK family of cell junction proteins. Development 122:97-111.
13. Hsueh YP, Yang C, Kharazia V, Naisbitt S, Cohen AR, Weinberg RJ, Sheng M (1998) Direct interaction of CASK/LIN-2 and syndecan heparan sulfate proteoglycan and their overlapping distribution in neuronal synapses. J Cell Biol 142:139-151.
14. Hsueh YP, Wang TF, Yang FC, Sheng M (2000) Nuclear translocation and transcription regulation by the membrane-associated guanylate kinase CASK/LIN-2. Nature 404:298-302.
15. Kaech SM, Whitfield CW, Kim SK (1998) The LIN-2/LIN-7/LIN-10 complex mediates basolateral membrane localization of the C. elegans EGF receptor LET-23 in vulval epithelial cells. Cell 94:761-771.
16. Kim SK (1997) Polarized signaling: basolateral receptor localization in epithelial cells by PDZ-containing proteins. Curr Opin Cell Biol 9:853-859.
17. Laemmli UK (1970) Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227:680-685.
18. Laverty HG, Wilson JB (1998) Murine CASK is disrupted in a sex-linked cleft palate mouse mutant. Genomics 53:29-41.
19. Martinez-Estrada OM, Villa A, Breviario F, Orsenigo F, Dejana E, Bazzoni G (2001) Association of junctional adhesion molecule with calcium/calmodulin-dependent serine protein kinase (CASK/LIN-2) in human epithelial caco-2 cells. J Biol Chem 276:9291-9296.
20. Maximov A, Sudhof TC, Bezprozvanny I (1999) Association of neuronal calcium channels with modular adaptor proteins. J Biol Chem 274:24453-24456.
21. McLoughlin DM, Miller CC (1996) The intracellular cytoplasmic domain of the Alzheimer's disease amyloid precursor protein interacts with phosphotyrosine-binding domain proteins in the yeast two-hybrid system. FEBS Lett 397:197-200.
22. Nix SL, Chishti AH, Anderson JM, Walther Z (2000) hCASK and hDlg associate in epithelia, and their src homology 3 and guanylate kinase domains participate in both intramolecular and intermolecular interactions. J Biol Chem 275:41192-41200.
23. Okamoto M, Südhof TC (1997) Mints, munc18-interacting proteins in synaptic vesicle exocytosis. J Biol Chem 272:31459-31464.
24. Pawson T, Nash P (2000) Protein-protein interactions define specificity in signal transduction. Genes Dev 14:1027-1047.
25. Rongo C, Whitfield CW, Rodal A, Kim SK, Kaplan JM (1998) LIN-10 is a shared component of the polarized protein localization pathways in neurons and epithelia. Cell 94:751-759.
26. Rosahl TW, Spillane D, Missler M, Herz J, Selig DK, Wolff JR, Hammer RE, Malenka RC, Südhof TC (1995) Essential functions of synapsins I and II in synaptic vesicle regulation. Nature 375:488-493.
27. Sambrook J, Fritsch EF, Maniatis T (1989) Molecular cloning: a laboratory manual. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory.
28. Setou M, Nakagawa T, Seog DH, Hirokawa N (2000) Kinesin superfamily motor protein KIF17 and mLin-10 in NMDA receptor-containing vesicle transport. Science 288:1796-1802.
29. Sheng M, Sala C (2001) Pdz domains and the organization of supramolecular complexes. Annu Rev Neurosci 24:1-29.
30. Tseng TC, Marfatia SM, Bryant PJ, Pack S, Zhuang Z, O'Brien JE, Lin L, Hanada T, Chishti AH (2001) VAM-1: a new member of the MAGUK family binds to human Veli-1 through a conserved domain. Biochim Biophys Acta 1518:249-259.
31. Tsunoda S, Zuker CS (1999) The organization of INAD-signaling complexes by a multivalent PDZ domain protein in Drosophila photoreceptor cells ensures sensitivity and speed of signaling. Cell Calcium 26: 165-171.