Polycyclic quinones and hydroquinones, antitumor constituents from Taiwanese marine sponge Xestospongia sp.

Chinese Pharmaceutical Journal

Volumn 54, Issue 3, 2002, Pages 207-213

  Shen, Ya Ching ^a   Lo, Kuang Liang ^a   Kuo, Yao Haur ^a   Chakraborty, Rupak ^a  

^a NATIONAL SUN YAT SEN UNIVERSITY   (Taiwan)

Author keywords

Cytotoxicity; Hydroquinones; Quinones; Xestospongia

Indexed keywords

KETONES; SCREENING; TOXICITY;

CYTOTOXICITY;

DRUG PRODUCTS;

14 METHOXYXESTOQUINONE; 15 CHLORO 14 HYDROXYXESTOQUINONE; 15 METHOXYXESTOQUINONE; ADOCIAQUINONE A; ADOCIAQUINONE B; CYTOTOXIC AGENT; DACTINOMYCIN; HALENAQUINOL; HALENAQUINONE; HYDROQUINONE DERIVATIVE; MITOMYCIN C; NATURAL PRODUCT; QUINONE DERIVATIVE; UNCLASSIFIED DRUG; XESTOQUINONE;

ARTICLE; CANCER CELL CULTURE; DRUG CYTOTOXICITY; DRUG ISOLATION; DRUG STRUCTURE; HUMAN; HUMAN CELL; INFRARED SPECTROSCOPY; MARINE ENVIRONMENT; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; SPONGE (PORIFERA); TAIWAN; ULTRAVIOLET SPECTROSCOPY;

EID: 0036614546     PISSN: 10161015     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (8)

1. Xestoquinone, a novel cardiotonic marine natural product isolated from the Okinawan sea sponge Xestospongia sapra
2. Halenaquinol and halenaquinol sulfate, pentacyclic hydroquinones from the Okinawan marine sponge Xestospongia sapra
3. Xesto and halenaquinone derivatives from a sponge, Adocia sp. from Truk Lagoon
4. Protein tyrosine kinase inhibitory properties of planar polycyclics obtained from the marine sponge Xestospongia cf. Carbonaria and from total synthesis
5. Topoisomerase II mediated DNA cleavage by adocia- and xestoquinones from Philippine sponge Xestospongia sp.
6. Structures and cytotoxicity relationship of isoaaptamine and aaptamine derivatives
7. Evaluation of a soluble tetrazolium / formazan assay for cell growth and drug sensitivity in culture using human and other tumor cell lines