Sexual dimorphic expression of mouse hepatic CYP2B: Alterations during development or after hypophysectomy

Biochemical Pharmacology

Volumn 63, Issue 11, 2002, Pages 2037-2041

  Jarukamjorn, Kanokwan ^a   Sakuma, Tsutomu ^a   Nemoto, Nobuo ^a  

^a KHON KAEN UNIVERSITY   (Thailand)

Author keywords

CYP2B; Development; Expression; Hypophysectomy; Sex hormones; Sexual dimorphism

Indexed keywords

CYTOCHROME P450 2B; CYTOCHROME P450 2B9; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; FEMALE; HYPOPHYSECTOMY; LIVER CELL; MALE; MATURATION; MOUSE; NONHUMAN; PREPUBERTY; PRIORITY JOURNAL; PROTEIN EXPRESSION; SEX DIFFERENCE;

ANIMALS; ARYL HYDROCARBON HYDROXYLASES; CYTOCHROME P-450 ENZYME SYSTEM; FEMALE; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HYPOPHYSECTOMY; MALE; MICE; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SEX FACTORS; STEROID HYDROXYLASES;

EID: 0036609581     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-2952(02)00989-9     Document Type: Article

References (20)

1. Glucocorticoid and sex hormones as activating or modulating factors for expression of Cyp2b-9 and Cyp2b-10 in the mouse liver and hepatocytes
2. Different regulation of the expression of mouse hepatic cytochrome P450 2B enzymes by glucocorticoid and phenobarbital
3. Sex-associated expression of the mouse hepatic and renal CYP2B enzymes by glucocorticoid hormone
4. Discriminating activation of CYP2B9 expression in male C57BL/6 mouse liver by β-estradiol
5. Effect of ovariectomy and androgen on phenobarbital induction of hepatic CYP2B1 and CYP2B2 in Sprague-Dawley rats
6. Suppression of levels of phenobarbital-inducible rat liver cytochrome P450 by pituitary hormone
7. Regulation of phenobarbital-inducible cytochrome P-450s in rat and mouse liver following dexamethasone administration and hypophysectomy
8. Hormonal regulation of rat liver microsomal enzymes
9. Gender differences in the responsiveness of the sex-dependent isoforms of hepatic P450 to the feminine plasma growth hormone profile
10. Sex differences in the ultradian pattern of plasma growth hormone concentrations in mice
11. Interpulse interval in circulating growth hormone patterns regulates sexually dimorphic expression of hepatic cytochrome P450
12. Pretranslation regulation of sex-dependent testosterone hydroxylase by growth hormone in mouse liver
13. 1,4-Bis[2-(3,5-dichloropyridyloxy)]benzene, an extremely potent modulator of mouse hepatic cytochrome P450 gene expression
14. Interactions of gender, growth hormone, and phenobarbital induction on murine Cyp2b expression
15. Localization of estradiol-responsive region in the phenobarbital-responsive enhancer module of mouse Cyp2b10 gene
16. Estrogen activation of the nuclear orphan receptor CAR (constitutive active receptor) in induction of the mouse Cyp2b10 gene
17. Intermittent plasma growth hormone triggers tyrosine phosphorylation and nuclear translocation of a liver-expressed, STAT5-related DNA binding protein. Proposed role as an intracellular regulator of male-specific liver gene transcription
18. Distinctive roles of STAT5a and STAT5b in sexual dimorphism of hepatic P450 gene expression
19. Requirement of STAT5b for sexual dimorphism of body growth rates and liver gene expression
20. STAT5b deficient mice are growth hormone pulse-resistant: Role of STAT5b in sex-specific liver P450 expression