Cellular hijacking: A common strategy for microbial infection

Trends in Biochemical Sciences

Volumn 27, Issue 6, 2002, Pages 308-314

  Kahn, Richard A ^a   Fu, Haian ^a   Roy, Craig R ^b  

^a EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIN RELATED PROTEIN 2; ACTIN RELATED PROTEIN 3; ADENOSINE DIPHOSPHATE RIBOSYLATION FACTOR; BACTERIAL PROTEIN; CALCIUM ION; CHOLERA TOXIN; CYCLIC AMP; ESCHERICHIA COLI ENTEROTOXIN; EXOENZYME S; G ACTIN; GANGLIOSIDE GM1; GUANINE NUCLEOTIDE BINDING PROTEIN; GUANOSINE TRIPHOSPHATASE; GUANOSINE TRIPHOSPHATASE ACTIVATING PROTEIN; MEMBRANE PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE 1; NICOTINAMIDE ADENINE DINUCLEOTIDE; PROTEIN 14 3 3; PROTEIN ACTA; PROTEIN CDC42; PROTEIN DISULFIDE ISOMERASE; PROTEIN RALF; RAB PROTEIN; RAC1 PROTEIN; RAP PROTEIN; RAS PROTEIN; RHO FACTOR; SYNAPTOTAGMIN VII; UNCLASSIFIED DRUG; UNINDEXED DRUG; VASODILATOR STIMULATED PHOSPHOPROTEIN;

ACTIN POLYMERIZATION; ENDOCYTOSIS; ENZYME ACTIVITY; EUKARYOTIC CELL; HOST PATHOGEN INTERACTION; HUMAN; INFECTION; INTOXICATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN TRANSPORT; REVIEW; SEQUENCE HOMOLOGY; VIRULENCE;

ADP RIBOSE TRANSFERASES; ANIMALS; BACTERIA; BACTERIAL ADHESION; ENDOCYTOSIS; ENTEROTOXINS; HUMANS; INFECTION; MODELS, BIOLOGICAL;

BACTERIA (MICROORGANISMS); ESCHERICHIA COLI; EUKARYOTA;

EID: 0036607439     PISSN: 09680004     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0968-0004(02)02108-4     Document Type: Review

References (60)

1. Origin and evolution of the mitochondrial proteome
2. Structural mimicry in bacterial virulence
3. Pathogenic trickery: Deception of host cell processes
4. AB5 toxins
5. 1-ganglioside but lacks immunomodulatory or toxic activity
6. 5 quaternary structure of cholera toxin
7. Protein disulfide isomerase acts as a redox-dependent chaperone to unfold cholera toxin
8. Cholera toxin is exported from microsomes by the Sec61p complex
9. Purification of a protein cofactor required for ADP-ribosylation of the stimulatory regulatory component of adenylate cyclase by cholera toxin
10. ARF binds the C-terminal region of the Escherichia coli heat-labile toxin (LTA1) and competes for the binding of LTA2
11. Involvement of nicotinamide adenine dinucleotide in the action of cholera toxin in vitro
12. Mechanism of action of choleragen. Evidence for ADP-ribosyltransferase activity with arginine as an acceptor
13. Mechanism of cholera toxin action: Covalent modification of the guanyl nucleotide-binding protein of the adenylate cyclase system
14. ADP-ribosylation of Gs promotes the dissociation of its α and β subunits
15. Therapeutic guidelines for Pseudomonas aeruginosa infections
16. Pseudomonas aeruginosa exoenzyme S requires a eukaryotic protein for ADP-ribosyltransferase activity
17. Pseudomonas aeruginosa exoenzyme S, a bifunctional type-III secreted cytotoxin
18. Exoenzyme S of Pseudomonas aeruginosa is secreted by a type III pathway
19. The role of exoenzyme S in infections with Pseudomonas aeruginosa
20. The N-terminal domain of Pseudomonas aeruginosa exoenzyme S is a GTPase-activating protein for Rho GTPases
21. Pseudomonas aeruginosa exoenzyme S: An adenosine diphosphate ribosyltransferase distinct from toxin A
22. The eukaryotic host factor that activates exoenzyme S of Pseudomonas aeruginosa is a member of the 14-3-3 protein family
23. 14-3-3 proteins are required for the inhibition of Ras by exoenzyme S
24. 14-3-3 proteins mediate an essential anti-apoptotic signal
25. How the Pseudomonas aeruginosa ExoS toxin down regulates Rac
26. Modulation of host signaling by a bacterial mimic: Structure of the Salmonella effector SptP bound to Rac1
27. GAP activity of the Yersinia YopE cytotoxin specifically targets the Rho pathway: A mechanism for disruption of actin microfilament structure
28. ras and related proteins by Pseudomonas aeruginosa exoenzyme S
29. Pseudomonas aeruginosa exoenzyme S disrupts Ras-mediated signal transduction by inhibiting guanine nucleotide exchange factor-catalyzed nucleotide exchange
30. Ras effector pathway activation by epidermal growth factor is inhibited in vivo by exoenzyme S ADP-ribosylation of Ras
31. 14-3-3 proteins: Structure, function, and regulation
32. Intracellular expression of the ADP- ribosyltransferase domain of Pseudomonas exoenzyme S is cytotoxic to eukaryotic cells
33. Independent and coordinate effects of ADP-ribosyltransferase and GTPase-activating activities of exoenzyme S on HT-29 epithelial cell function
34. Pseudomonas aeruginosa mediated apoptosis requires the ADP-ribosylating activity of ExoS
35. The use of host cell machinery in the pathogenesis of Listeria monocytogenes
36. Actin filaments and the growth, movement, and spread of the intracellular bacterial parasite, Listeria monocytogenes
37. Listeria monocytogenes exploits normal host cell processes to spread from cell to cell
38. L. monocytogenes-induced actin assembly requires the ActA gene product, a surface protein
39. Reconstitution of actin-based motility of Listeria and Shigella using pure proteins
40. Three regions within ActA promote Arp2/3 complex-mediated actin nucleation and Listeria monocytogenes motility
41. A focal adhesion factor directly linking intracellularly motile Listeria monocytogenes and Listeria ivanovii to the actin-based cytoskeleton of mammalian cells
42. The tandem repeat domain in the Listeria monocytogenes ActA protein controls the rate of actin-based motility, the percentage of moving bacteria, and the localization of vasodilator-stimulated phosphoprotein and profilin
43. The molecular ecology of legionellae
44. Legionnaires' disease: Isolation of a bacterium and demonstration of its role in other respiratory diseases
45. Modulation of phagosome biogenesis by Legionella pneumophila creates an organelle permissive for intracellular growth
46. The Legionnaires' disease bacterium (Legionella pneumophila) inhibits phagosome lysosome fusion in human monocytes
47. How the parasitic bacterium Legionella pneumophila modifies its phagosome and transforms it into rough ER: Implications for conversion of plasma membrane to the ER membrane
48. A bacterial guanine nucleotide exchange factor activates ARF on Legionella phagosomes
49. Formation of a novel phagosome by the Legionnaires' disease bacterium (Legionella pneumophila) in human monocytes
50. Signaling and host cell invasion by Trypanosoma cruzi
51. Lysosome recruitment and fusion are early events required for trypanosome invasion of mammalian cells
52. 2+ transients
53. 2+-signaling factor for mammalian cells
54. 2+-regulated exocytic vesicles in fibroblasts and epithelial cells
55. 2+-dependent and -independent activities of neural and non-neural synaptotagmins
56. 2+-dependent exocytosis of lysosomes in fibroblasts
57. The exocytosis-regulatory protein synaptotagmin VII mediates cell invasion by Trypanosoma cruzi
58. Calcium-regulated exocytosis is required for cell membrane resealing
59. Cell membrane resealing by a vesicular mechanism similar to neurotransmitter release
60. 2+-regulated exocytosis of lysosomes