메뉴 건너뛰기




Volumn 1, Issue 6, 2002, Pages 447-456

Encoding microcarriers: Present and future technologies

Author keywords

[No Author keywords available]

Indexed keywords

ALUMINUM; CADMIUM DERIVATIVE; DNA; DRUG CARRIER; EPOTHILONE DERIVATIVE; METAL COMPLEX; MICROSPHERE; NICKEL; PACLITAXEL; PACLITAXEL DERIVATIVE; PALLADIUM; POLYELECTROLYTE; RUTHENIUM COMPLEX; SELENIDE; ZINC SULFIDE;

EID: 0036599469     PISSN: 14741776     EISSN: None     Source Type: Journal    
DOI: 10.1038/nrd817     Document Type: Review
Times cited : (274)

References (91)
  • 1
    • 0036371327 scopus 로고    scopus 로고
    • Protein microarray technology
    • Stoll, D. et al. Protein microarray technology. Front. Biosci. 7 C13-C32 (2002).
    • (2002) Front. Biosci. , vol.7
    • Stoll, D.1
  • 2
    • 0034659898 scopus 로고    scopus 로고
    • Genomics, gene expression and DNA arrays
    • Lockhart, D. J. & Winzeler, E. A. Genomics, gene expression and DNA arrays. Nature 405, 827-836 (2000).
    • (2000) Nature , vol.405 , pp. 827-836
    • Lockhart, D.J.1    Winzeler, E.A.2
  • 3
    • 84984932472 scopus 로고    scopus 로고
    • Exploring the new world of the genome with DNA microarrays
    • Brown, P. O. & Botstein, D. Exploring the new world of the genome with DNA microarrays. Nature Genet. 21 (Suppl. 1), 33-37 (1999).
    • (1999) Nature Genet. , vol.21 , Issue.SUPPL. 1 , pp. 33-37
    • Brown, P.O.1    Botstein, D.2
  • 5
    • 0032906005 scopus 로고    scopus 로고
    • Combinatorial libraries by portioning and mixing
    • Furka, A. & Bennett, W. D. Combinatorial libraries by portioning and mixing. Com. Chem. High. T. Scr. 2, 105-122 (1999).
    • (1999) Com. Chem. High. T. Scr. , vol.2 , pp. 105-122
    • Furka, A.1    Bennett, W.D.2
  • 7
    • 0031151960 scopus 로고    scopus 로고
    • New methods in combinatorial chemistry - Robotics and parallel synthesis
    • Cargill, J. F. & Lebl, M. New methods in combinatorial chemistry - robotics and parallel synthesis. Curr. Opin. Chem. Biol. 1, 67-71 (1997).
    • (1997) Curr. Opin. Chem. Biol. , vol.1 , pp. 67-71
    • Cargill, J.F.1    Lebl, M.2
  • 8
    • 18944378492 scopus 로고    scopus 로고
    • Glossary of terms used in combinatorial chemistry
    • Maclean, D. et al. Glossary of terms used in combinatorial chemistry. Pure Appl. Chem. 71, 2349-2365 (1999).
    • (1999) Pure Appl. Chem. , vol.71 , pp. 2349-2365
    • Maclean, D.1
  • 9
    • 0000577984 scopus 로고    scopus 로고
    • The "one-bead-one-compound" combinatorial library method
    • Lam, K. S., Lebl, M. & Krchnak, V. The "one-bead-one-compound" combinatorial library method. Chem. Rev. 97, 411-448 (1997).
    • (1997) Chem. Rev. , vol.97 , pp. 411-448
    • Lam, K.S.1    Lebl, M.2    Krchnak, V.3
  • 10
    • 0025893762 scopus 로고
    • General method for rapid synthesis of multicomponent peptide mixtures
    • Furka, A., Sebestyen, F, Asgedom, M. & Dibo, G. General method for rapid synthesis of multicomponent peptide mixtures. Int. J. Prot. Res. 37, 487-493 (1991).
    • (1991) Int. J. Prot. Res. , vol.37 , pp. 487-493
    • Furka, A.1    Sebestyen, F.2    Asgedom, M.3    Dibo, G.4
  • 11
    • 0027362628 scopus 로고
    • Complex synthetic chemical libraries indexed with molecular tags
    • Ohlmeyer, M. H. J. et al. Complex synthetic chemical libraries indexed with molecular tags. Proc. Natl. Acad. Sci. USA 90, 10922-10926 (1993).
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 10922-10926
    • Ohlmeyer, M.H.J.1
  • 12
    • 0029873825 scopus 로고    scopus 로고
    • Versatile approach to encoding combinatorial organic syntheses using chemically robust secondary amine tags
    • Ni, Z.-J. et al. Versatile approach to encoding combinatorial organic syntheses using chemically robust secondary amine tags. J. Med. Chem. 39, 1601-1608 (1996).
    • (1996) J. Med. Chem. , vol.39 , pp. 1601-1608
    • Ni, Z.-J.1
  • 13
    • 0027597947 scopus 로고
    • Peptide encoding for structure determination of nonsequenceable polymers within libraries synthesized and tested on solid-phase supports
    • Nikolaiev, V. et al. Peptide encoding for structure determination of nonsequenceable polymers within libraries synthesized and tested on solid-phase supports. Peptide Res. 6, 161-170 (1993).
    • (1993) Peptide Res. , vol.6 , pp. 161-170
    • Nikolaiev, V.1
  • 14
    • 0033925288 scopus 로고    scopus 로고
    • Ligand discovery using encoded combinatorial libraries
    • Tan, D. S. & Burbaum, J. J. Ligand discovery using encoded combinatorial libraries. Curr. Opin. Drug Disc. Devel. 3, 439-453 (2000).
    • (2000) Curr. Opin. Drug Disc. Devel. , vol.3 , pp. 439-453
    • Tan, D.S.1    Burbaum, J.J.2
  • 15
    • 0027375520 scopus 로고
    • Generation and screening of an oligonucleotide-encoded synthetic peptide library
    • Needles, M. C. et al. Generation and screening of an oligonucleotide-encoded synthetic peptide library. Proc. Natl Acad. Sci. USA 90, 10700-10704 (1993).
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 10700-10704
    • Needles, M.C.1
  • 16
    • 0035958572 scopus 로고    scopus 로고
    • Capillary electrochromatography-laser-induced fluorescence method for separation and detection of dansylated dialkylamine tags in encoded combinatiorial libraries
    • Liu, X. et al. Capillary electrochromatography-laser-induced fluorescence method for separation and detection of dansylated dialkylamine tags in encoded combinatiorial libraries. J. Chromatogr. A 924, 323-329 (2001).
    • (2001) J. Chromatogr. A , vol.924 , pp. 323-329
    • Liu, X.1
  • 17
    • 0001117151 scopus 로고    scopus 로고
    • Improved methods for encoding and decoding dialkylamine-encoded combinatorial libraries
    • Fitch, W. L. et al. Improved methods for encoding and decoding dialkylamine-encoded combinatorial libraries. J. Comb. Chem. 1, 188-194 (1999).
    • (1999) J. Comb. Chem. , vol.1 , pp. 188-194
    • Fitch, W.L.1
  • 18
    • 0031151959 scopus 로고    scopus 로고
    • Encoding methods for combinatorial chemistry
    • Czarnik, A. W. Encoding methods for combinatorial chemistry. Curr. Opin. Chem. Biol. 1, 60-66 (1997).
    • (1997) Curr. Opin. Chem. Biol. , vol.1 , pp. 60-66
    • Czarnik, A.W.1
  • 19
    • 23444457432 scopus 로고
    • A mass spectrometric solution to the address problem of combinatorial libraries
    • Brummel, C. L., Lee, I. N. W., Zhou Y., Benkovic, S. J. & Winograd, N. A mass spectrometric solution to the address problem of combinatorial libraries. Science 264, 399-402 (1994).
    • (1994) Science , vol.264 , pp. 399-402
    • Brummel, C.L.1    Lee, I.N.W.2    Zhou, Y.3    Benkovic, S.J.4    Winograd, N.5
  • 20
    • 0028229329 scopus 로고
    • Microchemical structural determination of a peptoid covalently bound to a polymeric bead by matrix-assisted laser desorption ionization time-of-flight mass spectroscopy
    • Zambias, R. A., Boulton, D. A. & Griffin, P. R. Microchemical structural determination of a peptoid covalently bound to a polymeric bead by matrix-assisted laser desorption ionization time-of-flight mass spectroscopy. Tetrahedron Lett. 35, 4283-4286 (1994).
    • (1994) Tetrahedron Lett. , vol.35 , pp. 4283-4286
    • Zambias, R.A.1    Boulton, D.A.2    Griffin, P.R.3
  • 21
    • 0029109073 scopus 로고
    • Generation and screening of combinatorial peptide libraries designed for rapid sequencing by mass spectrometry
    • Youngquist, R. S., Fuentes G. R., Lacey, M. P. & Keough, T. Generation and screening of combinatorial peptide libraries designed for rapid sequencing by mass spectrometry. J. Am. Chem. Soc. 117, 3900-3906 (1995).
    • (1995) J. Am. Chem. Soc. , vol.117 , pp. 3900-3906
    • Youngquist, R.S.1    Fuentes, G.R.2    Lacey, M.P.3    Keough, T.4
  • 22
    • 9044227620 scopus 로고    scopus 로고
    • Evaluation of mass spectrometric methods applicable to the direct analysis of non-peptide bead-bound combinatorial libraries
    • Brummel, C. L. et al. Evaluation of mass spectrometric methods applicable to the direct analysis of non-peptide bead-bound combinatorial libraries. Anal. Chem. 68, 237-242 (1996).
    • (1996) Anal. Chem. , vol.68 , pp. 237-242
    • Brummel, C.L.1
  • 23
    • 37049078898 scopus 로고
    • Linkers for combinatorial chemistry and reaction analysis using solid phase in situ mass spectrometry
    • Egner, B. J., Cardno, M. & Bradley, M. Linkers for combinatorial chemistry and reaction analysis using solid phase in situ mass spectrometry. J. Chem. Soc. Chem. Commun. 21, 2163-2164 (1995).
    • (1995) J. Chem. Soc. Chem. Commun. , vol.21 , pp. 2163-2164
    • Egner, B.J.1    Cardno, M.2    Bradley, M.3
  • 24
    • 33751154773 scopus 로고
    • Solid phase chemistry: Direct monitoring by matrix-assisted laser desorption/ionization time of flight mass spectrometry. A tool for combinatorial chemistry
    • Egner, B. J., Langley, G. J. & Bradley, M. Solid phase chemistry: direct monitoring by matrix-assisted laser desorption/ionization time of flight mass spectrometry. A tool for combinatorial chemistry. J. Org. Chem, 60, 2652-2653 (1995).
    • (1995) J. Org. Chem. , vol.60 , pp. 2652-2653
    • Egner, B.J.1    Langley, G.J.2    Bradley, M.3
  • 25
    • 80052130082 scopus 로고    scopus 로고
    • Isotope or mass encoding of combinatorial libraries
    • Geysen, H. M. et al. Isotope or mass encoding of combinatorial libraries. Chem. Biol. 3, 679-688 (1996).
    • (1996) Chem. Biol. , vol.3 , pp. 679-688
    • Geysen, H.M.1
  • 26
    • 0034697160 scopus 로고    scopus 로고
    • Trityl tags for encoding in combinatorial synthesis
    • Shchepinov, M. S., Chalk, R. & Southern, E. M. Trityl tags for encoding in combinatorial synthesis. Tetrahedron 56, 2713-2724 (2000).
    • (2000) Tetrahedron , vol.56 , pp. 2713-2724
    • Shchepinov, M.S.1    Chalk, R.2    Southern, E.M.3
  • 28
    • 0000495922 scopus 로고    scopus 로고
    • Encoding of combinatorial chemistry libraries by fluorine-19 NMR
    • Hochlowski, J. E., Whittern, D. N. & Sowin, T. J. Encoding of combinatorial chemistry libraries by fluorine-19 NMR. J. Comb. Chem. 1, 291-293 (1999).
    • (1999) J. Comb. Chem. , vol.1 , pp. 291-293
    • Hochlowski, J.E.1    Whittern, D.N.2    Sowin, T.J.3
  • 29
    • 0032795809 scopus 로고    scopus 로고
    • Elemental analysis of individual combinatorial chemistry library members by energy-dispersive X-ray spectroscopy
    • Neilly, J. P. & Hochlowski, J. E. Elemental analysis of individual combinatorial chemistry library members by energy-dispersive X-ray spectroscopy. Appl. Spectrosc. 53, 74-81 (1999).
    • (1999) Appl. Spectrosc. , vol.53 , pp. 74-81
    • Neilly, J.P.1    Hochlowski, J.E.2
  • 30
    • 0000411330 scopus 로고    scopus 로고
    • Infrared and Raman spectra of a single resin bead for analysis of solid-phase reactions and use in encoding combinatorial libraries
    • Rahman, S. S., Busby, D. J. & Lee, D. C. Infrared and Raman spectra of a single resin bead for analysis of solid-phase reactions and use in encoding combinatorial libraries. J. Org. Chem. 63, 6196-6199 (1998).
    • (1998) J. Org. Chem. , vol.63 , pp. 6196-6199
    • Rahman, S.S.1    Busby, D.J.2    Lee, D.C.3
  • 31
    • 0032087667 scopus 로고    scopus 로고
    • Coloured peptides: Synthesis, properties and use in preparation of peptide sub-library kits
    • Sebestyen, F. et al. Coloured peptides: synthesis, properties and use in preparation of peptide sub-library kits. J. Pept. Sci. 4, 294-299 (1998).
    • (1998) J. Pept. Sci. , vol.4 , pp. 294-299
    • Sebestyen, F.1
  • 32
    • 1842814134 scopus 로고    scopus 로고
    • Tagging in combinatorial chemistry: The use of coloured and fluorescent beads
    • Egner, B. J. et al. Tagging in combinatorial chemistry: the use of coloured and fluorescent beads. Chem. Commun. 8, 735-736 (1997).
    • (1997) Chem. Commun. , vol.8 , pp. 735-736
    • Egner, B.J.1
  • 33
    • 0035806606 scopus 로고    scopus 로고
    • Novel colloidal materials for high-throughput screening applications in drug discovery and genomics
    • Trau, M. & Battersby, B. J. Novel colloidal materials for high-throughput screening applications in drug discovery and genomics. Adv. Mater. 13, 975-979 (2001).
    • (2001) Adv. Mater. , vol.13 , pp. 975-979
    • Trau, M.1    Battersby, B.J.2
  • 34
    • 0010602899 scopus 로고    scopus 로고
    • Optical encoding of microbeads for gene screening: Alternatives to microarrays
    • (HTS Suppl.)
    • Battersby, B. J., Lawrie, G. A. & Trau, M. Optical encoding of microbeads for gene screening: alternatives to microarrays. Drug Discov. Today 6 (HTS Suppl.), 19-26 (2001).
    • (2001) Drug Discov. Today , vol.6 , pp. 19-26
    • Battersby, B.J.1    Lawrie, G.A.2    Trau, M.3
  • 35
    • 0034620738 scopus 로고    scopus 로고
    • Toward larger chemical libraries: Encoding with fluorescent colloids in combinatorial chemistry
    • Battersby, B. J. et al. Toward larger chemical libraries: encoding with fluorescent colloids in combinatorial chemistry. J. Am. Chem. Soc. 122, 2138-2139 (2000).
    • (2000) J. Am. Chem. Soc. , vol.122 , pp. 2138-2139
    • Battersby, B.J.1
  • 36
    • 0034516088 scopus 로고    scopus 로고
    • Encoding combinatorial libraries: A novel application of fluorescent silica colloids
    • Grondahl, L., Battersby, B. J., Bryant, D. & Trau, M. Encoding combinatorial libraries: a novel application of fluorescent silica colloids. Langmuir 16, 9709-9715 (2000).
    • (2000) Langmuir , vol.16 , pp. 9709-9715
    • Grondahl, L.1    Battersby, B.J.2    Bryant, D.3    Trau, M.4
  • 37
    • 0030776426 scopus 로고    scopus 로고
    • Advanced multiplexed analysis with the FlowMetrix™ system
    • Fulton, R. J. et al. Advanced multiplexed analysis with the FlowMetrix™ system. Clin. Chem. 43, 1749-1756 (1997).
    • (1997) Clin. Chem. , vol.43 , pp. 1749-1756
    • Fulton, R.J.1
  • 38
    • 0032189266 scopus 로고    scopus 로고
    • Classification and properties of 64 multiplexed microsphere sets
    • Kettman, J. R., Davies, T., Chandler, D., Oliver, K. G. & Fulton, R. J. Classification and properties of 64 multiplexed microsphere sets. Cytometry 33, 234-243 (1998).
    • (1998) Cytometry , vol.33 , pp. 234-243
    • Kettman, J.R.1    Davies, T.2    Chandler, D.3    Oliver, K.G.4    Fulton, R.J.5
  • 39
    • 0036469895 scopus 로고    scopus 로고
    • Simultaneous quantification of proinflammatory cytokines in human plasma using the LabMAP (TM) assay
    • Prabhakar, U., Eirikis, E. & Davis, H. M. Simultaneous quantification of proinflammatory cytokines in human plasma using the LabMAP (TM) assay. J. Immunol. Methods 260, 207-218 (2002).
    • (2002) J. Immunol. Methods , vol.260 , pp. 207-218
    • Prabhakar, U.1    Eirikis, E.2    Davis, H.M.3
  • 40
    • 0036146140 scopus 로고    scopus 로고
    • Development of internal controls for the Luminex instrument as part of a multiplex seven-analyte viral respiratory antibody profile
    • Martins, T. B. Development of internal controls for the Luminex instrument as part of a multiplex seven-analyte viral respiratory antibody profile. Clin. Diagn. Lab. Immun. 9, 41-45 (2002).
    • (2002) Clin. Diagn. Lab. Immun. , vol.9 , pp. 41-45
    • Martins, T.B.1
  • 41
    • 0035071595 scopus 로고    scopus 로고
    • Fluorescent microsphere-based readout technology for multiplexed human single nucleotide polymorphism analysis and bacterial identification
    • Ye, F. et al. Fluorescent microsphere-based readout technology for multiplexed human single nucleotide polymorphism analysis and bacterial identification. Hum. Mutat. 17, 305-316 (2001).
    • (2001) Hum. Mutat. , vol.17 , pp. 305-316
    • Ye, F.1
  • 42
    • 0035092024 scopus 로고    scopus 로고
    • Flow cytometric platform for high-throughput single nucleotide polymorphism analysis
    • Taylor, J. D. et al. Flow cytometric platform for high-throughput single nucleotide polymorphism analysis. Biotechniques 30, 661-675 (2001).
    • (2001) Biotechniques , vol.30 , pp. 661-675
    • Taylor, J.D.1
  • 43
    • 0034747127 scopus 로고    scopus 로고
    • BADGE, BeadsArray for the detection of gene expression, a high-throughput diagnostic bioassay
    • Yang, L., Tran, D. K. & Wang, X. BADGE, BeadsArray for the detection of gene expression, a high-throughput diagnostic bioassay. Genome Res. 11, 1888-1898 (2001).
    • (2001) Genome Res. , vol.11 , pp. 1888-1898
    • Yang, L.1    Tran, D.K.2    Wang, X.3
  • 44
    • 0000408707 scopus 로고    scopus 로고
    • Application of the Luminex LabMAP in rapid screening for mutations in the cystic fibrosis transmembrane conductance regulator gene: A pilot study
    • Dunbar, S. A. & Jacobson, J. W. Application of the Luminex LabMAP in rapid screening for mutations in the cystic fibrosis transmembrane conductance regulator gene: a pilot study. Clin. Chem. 46, 1498-1500 (2000).
    • (2000) Clin. Chem. , vol.46 , pp. 1498-1500
    • Dunbar, S.A.1    Jacobson, J.W.2
  • 45
    • 0034699375 scopus 로고    scopus 로고
    • Multiplexed particle-based flow cytometric, assays
    • Vignali D. A. A. Multiplexed particle-based flow cytometric, assays. J. Immunol. Methods 243, 243-255 (2000).
    • (2000) J. Immunol. Methods , vol.243 , pp. 243-255
    • Vignali, D.A.A.1
  • 46
    • 0032856945 scopus 로고    scopus 로고
    • Simultaneous quantitation of 15 cytokines using a multiplexed flow cytometric assay
    • Carson, R. T. & Vignali, D. A. A. Simultaneous quantitation of 15 cytokines using a multiplexed flow cytometric assay. J. Immunol. Methods 227, 41-52 (1999).
    • (1999) J. Immunol. Methods , vol.227 , pp. 41-52
    • Carson, R.T.1    Vignali, D.A.A.2
  • 47
    • 0030870964 scopus 로고    scopus 로고
    • Multiplexed quantification of human IgG, IgA, and IgM with the FlowMetrix(TM) system
    • Gordon, R. F. & McDade, R. L. Multiplexed quantification of human IgG, IgA, and IgM with the FlowMetrix(TM) system. Clin. Chem. 43, 1799-1801 (1997).
    • (1997) Clin. Chem. , vol.43 , pp. 1799-1801
    • Gordon, R.F.1    McDade, R.L.2
  • 48
    • 0043164695 scopus 로고    scopus 로고
    • A novel rapid multiplexed assay for herpes simplex virus DNA using the FlowMetrix(TM) cytometric microsphere technology
    • WalkerPeach, C. R., Smith, P. L., DuBois, D. B. & Fulton, R. J. A novel rapid multiplexed assay for herpes simplex virus DNA using the FlowMetrix(TM) cytometric microsphere technology Clin. Chem. 43, 21-21 (1997).
    • (1997) Clin. Chem. , vol.43 , pp. 21
    • WalkerPeach, C.R.1    Smith, P.L.2    DuBois, D.B.3    Fulton, R.J.4
  • 49
    • 0031783422 scopus 로고    scopus 로고
    • A rapid, sensitive, multiplexed assay for detection of viral nucleic acids using the FlowMetrix system
    • Smith, P. L., WalkerPeach, C. R., Fulton, R. J. & DuBois, D. B. A rapid, sensitive, multiplexed assay for detection of viral nucleic acids using the FlowMetrix system. Clin. Chem. 44, 2054-2056 (1998).
    • (1998) Clin. Chem. , vol.44 , pp. 2054-2056
    • Smith, P.L.1    WalkerPeach, C.R.2    Fulton, R.J.3    DuBois, D.B.4
  • 50
    • 0031721423 scopus 로고    scopus 로고
    • Multiplexed analysis of human cytokines by use of the FlowMetrix system
    • Oliver, K. G., Kettman, J. R. & Fulton, R. J. Multiplexed analysis of human cytokines by use of the FlowMetrix system. Clin. Chem. 44, 2057-2060 (1998).
    • (1998) Clin. Chem. , vol.44 , pp. 2057-2060
    • Oliver, K.G.1    Kettman, J.R.2    Fulton, R.J.3
  • 51
    • 0033816504 scopus 로고    scopus 로고
    • Simultaneous measurement of thyroxine and thyrotropin from newborn dried blood-spot specimens using a multiplexed fluorescent microsphere immunoassay
    • Bellisario, R., Colinas, R. J. & Pass, K. A. Simultaneous measurement of thyroxine and thyrotropin from newborn dried blood-spot specimens using a multiplexed fluorescent microsphere immunoassay. Clin. Chem. 46, 1422-1424 (2000).
    • (2000) Clin. Chem. , vol.46 , pp. 1422-1424
    • Bellisario, R.1    Colinas, R.J.2    Pass, K.A.3
  • 52
    • 0000348596 scopus 로고    scopus 로고
    • Ordered nanowell arrays
    • Pantano, P. & Walt, D. R. Ordered nanowell arrays. Chem, Mater. 8, 2832-2835 (1996).
    • (1996) Chem. Mater. , vol.8 , pp. 2832-2835
    • Pantano, P.1    Walt, D.R.2
  • 53
    • 0034695268 scopus 로고    scopus 로고
    • Bead-based fiber-optic arrays
    • Walt, D. R. Bead-based fiber-optic arrays. Science 287, 451-452 (2000).
    • (2000) Science , vol.287 , pp. 451-452
    • Walt, D.R.1
  • 54
    • 0242388855 scopus 로고    scopus 로고
    • The use of optical-imaging fibers for the fabrication of array sensors
    • Michael, K. L. et al. The use of optical-imaging fibers for the fabrication of array sensors. Polymers in Sensors 690, 273-289 (1998).
    • (1998) Polymers in Sensors , vol.690 , pp. 273-289
    • Michael, K.L.1
  • 55
    • 0032043853 scopus 로고    scopus 로고
    • Randomly ordered addressable high-density optical sensor arrays
    • Michael, K. L., Taylor, L. C., Schultz, S. L. & Walt, D. R. Randomly ordered addressable high-density optical sensor arrays. Anal. Chem. 70, 1242-1248 (1998).
    • (1998) Anal. Chem. , vol.70 , pp. 1242-1248
    • Michael, K.L.1    Taylor, L.C.2    Schultz, S.L.3    Walt, D.R.4
  • 56
    • 0033988142 scopus 로고    scopus 로고
    • Screening unlabeled DNA targets with randomly ordered fiber-optic gene arrays
    • Steemers, F. J., Ferguson, J. A. & Walt, D. R. Screening unlabeled DNA targets with randomly ordered fiber-optic gene arrays. Nature Biotechnol. 18, 91-94 (2000).
    • (2000) Nature Biotechnol. , vol.18 , pp. 91-94
    • Steemers, F.J.1    Ferguson, J.A.2    Walt, D.R.3
  • 57
    • 0034669274 scopus 로고    scopus 로고
    • High-density fiber-optic DNA random microsphere array
    • Ferguson, J. A., Steemers, F. J. & Walt D. R. High-density fiber-optic DNA random microsphere array. Anal. Chem. 72, 5618-5624 (2000).
    • (2000) Anal. Chem. , vol.72 , pp. 5618-5624
    • Ferguson, J.A.1    Steemers, F.J.2    Walt, D.R.3
  • 58
    • 0029829687 scopus 로고    scopus 로고
    • A fiber-optic DNA biosensor microarray for the analysis of gene expression
    • Ferguson, J. A., Boles, T. C., Adams, C. P. & Walt, D. R. A fiber-optic DNA biosensor microarray for the analysis of gene expression. Nature Biotechnol. 14, 1681-1684 (1996).
    • (1996) Nature Biotechnol. , vol.14 , pp. 1681-1684
    • Ferguson, J.A.1    Boles, T.C.2    Adams, C.P.3    Walt, D.R.4
  • 59
    • 0031554899 scopus 로고    scopus 로고
    • Fiberoptic DNA sensor array capable of detecting point mutations
    • Healey, B. G., Matson, R. S. & Walt, D. R. Fiberoptic DNA sensor array capable of detecting point mutations. Anal. Biochem. 251, 270-279 (1997).
    • (1997) Anal. Biochem. , vol.251 , pp. 270-279
    • Healey, B.G.1    Matson, R.S.2    Walt, D.R.3
  • 60
    • 0035870824 scopus 로고    scopus 로고
    • A duplexed microsphere-based fluorescent immunoassay
    • Szurdoki, F., Michael, K. L. & Walt, D. R. A duplexed microsphere-based fluorescent immunoassay. Anal. Biochem. 291, 219-228 (2001).
    • (2001) Anal. Biochem. , vol.291 , pp. 219-228
    • Szurdoki, F.1    Michael, K.L.2    Walt, D.R.3
  • 61
    • 0012392952 scopus 로고    scopus 로고
    • Semiconductor nanocrystals as fluorescent biological labels
    • Bruchez, M., Moronne, M., Gin, P., Weiss, S. & Alivisatos A. P. Semiconductor nanocrystals as fluorescent biological labels. Science 281, 2013-2016 (1998).
    • (1998) Science , vol.281 , pp. 2013-2016
    • Bruchez, M.1    Moronne, M.2    Gin, P.3    Weiss, S.4    Alivisatos, A.P.5
  • 62
    • 0034941396 scopus 로고    scopus 로고
    • Quantum-dot-tagged microbeads for multiplexed optical coding of biomolecules
    • Han, M., Gao, X. H., Su, J. Z. & Nie, S. Quantum-dot-tagged microbeads for multiplexed optical coding of biomolecules. Nature Biotechnol. 19, 631-635 (2001).
    • (2001) Nature Biotechnol. , vol.19 , pp. 631-635
    • Han, M.1    Gao, X.H.2    Su, J.Z.3    Nie, S.4
  • 63
    • 0035458579 scopus 로고    scopus 로고
    • Less is more in medicine - Sophisticated forms of nanotechnology will find some of their first real-world applications in biomedical research, disease diagnosis and, possibly, therapy
    • Alivisatos, A. P. Less is more in medicine - sophisticated forms of nanotechnology will find some of their first real-world applications in biomedical research, disease diagnosis and, possibly, therapy. Sci. Am. 285, 66-73 (2001).
    • (2001) Sci. Am. , vol.285 , pp. 66-73
    • Alivisatos, A.P.1
  • 64
    • 0032212191 scopus 로고    scopus 로고
    • Flow cytometric characterization and classification of multiple dual-colour fluorescent microspheres using fluorescence lifetime
    • Keij J. F. & Steinkamp, J. A. Flow cytometric characterization and classification of multiple dual-colour fluorescent microspheres using fluorescence lifetime. Cytometry 33, 318-323 (1998).
    • (1998) Cytometry , vol.33 , pp. 318-323
    • Keij, J.F.1    Steinkamp, J.A.2
  • 65
    • 0035474390 scopus 로고    scopus 로고
    • A new type of phosphorescent nanospheres for use in advanced time-resolved multiplexed bioassays
    • Kürner, J. M., Klimant, I., Krause, C., Pringsheim, E. & Wolfbeis O. S. A new type of phosphorescent nanospheres for use in advanced time-resolved multiplexed bioassays. Anal. Biochem. 297, 32-41 (2001).
    • (2001) Anal. Biochem. , vol.297 , pp. 32-41
    • Kürner, J.M.1    Klimant, I.2    Krause, C.3    Pringsheim, E.4    Wolfbeis, O.S.5
  • 66
    • 0028815228 scopus 로고
    • Radio frequency tag encoded combiratorial library method for the discovery of tripeptide-substituted cinnamic acid inhibitors of the protein tyrosine phosphatase PTP1B
    • Moran, E. J. Radio frequency tag encoded combiratorial library method for the discovery of tripeptide-substituted cinnamic acid inhibitors of the protein tyrosine phosphatase PTP1B. J. Am. Chem. Soc. 117, 10787-10788 (1995).
    • (1995) J. Am. Chem. Soc. , vol.117 , pp. 10787-10788
    • Moran, E.J.1
  • 68
    • 0042162803 scopus 로고
    • Radio tags speed compound synthesis
    • Service, R. F. Radio tags speed compound synthesis. Science 270, 577 (1995).
    • (1995) Science , vol.270 , pp. 577
    • Service, R.F.1
  • 69
    • 0010694701 scopus 로고    scopus 로고
    • No static at all
    • Czarnik, T. & Nova, M. No static at all. Chem. Brit. 33, 39-41 (1997).
    • (1997) Chem. Brit. , vol.33 , pp. 39-41
    • Czarnik, T.1    Nova, M.2
  • 70
    • 0032401987 scopus 로고    scopus 로고
    • A combinatorial synthesis of tyrphostins via the 'directed sorting' method
    • Shi, S., Xiao, X. & Czarnik, A. W. A combinatorial synthesis of tyrphostins via the 'directed sorting' method. Biotechnol. Bioeng. 61, 7-12 (1998).
    • (1998) Biotechnol. Bioeng. , vol.61 , pp. 7-12
    • Shi, S.1    Xiao, X.2    Czarnik, A.W.3
  • 71
    • 0033949965 scopus 로고    scopus 로고
    • Solid-phase combinatorial synthesis using MicroCan reactors, rf tagging and directed sorting
    • Xiao, X. et al. Solid-phase combinatorial synthesis using MicroCan reactors, rf tagging and directed sorting. Biotechnol. Bioeng. 71, 44-50 (2000).
    • (2000) Biotechnol. Bioeng. , vol.71 , pp. 44-50
    • Xiao, X.1
  • 72
    • 0042663799 scopus 로고    scopus 로고
    • Downsizing DNA assays
    • Miller, K. Downsizing DNA assays. Scientist 16, 52-52 (2002).
    • (2002) Scientist , vol.16 , pp. 52
    • Miller, K.1
  • 73
    • 24544473118 scopus 로고    scopus 로고
    • Multiplex assay for nucleic acids employing transponders
    • US Patent 6,051,377
    • Mandecki, W. Multiplex assay for nucleic acids employing transponders. US Patent 6,051,377 (2000).
    • (2000)
    • Mandecki, W.1
  • 74
    • 0000478940 scopus 로고
    • General method for the rapid solid-phase synthesis of large numbers of peptides: Specificity of antigen-antibody interaction at the level of individual amino acids
    • Houghten, R. A. General method for the rapid solid-phase synthesis of large numbers of peptides: specificity of antigen-antibody interaction at the level of individual amino acids. Proc. Natl Acad. Sci. USA 82, 5131-5135 (1985).
    • (1985) Proc. Natl. Acad. Sci. USA , vol.82 , pp. 5131-5135
    • Houghten, R.A.1
  • 76
    • 0141468190 scopus 로고    scopus 로고
    • Bio-assay technique
    • WO Patent 00/16893
    • Dames, A., England, J. & Colby, E. Bio-assay technique. WO Patent 00/16893 (2000).
    • (2000)
    • Dames, A.1    England, J.2    Colby, E.3
  • 77
    • 0002022836 scopus 로고    scopus 로고
    • Solution and chips arrays in protein profiling
    • Zhou, H. H., Roy, S., Schulman, H. & Natan, M. J. Solution and chips arrays in protein profiling. Trends Biotechnol. 19 (Suppl.), 34-39 (2001).
    • (2001) Trends Biotechnol. , vol.19 , Issue.SUPPL. , pp. 34-39
    • Zhou, H.H.1    Roy, S.2    Schulman, H.3    Natan, M.J.4
  • 78
    • 0032625830 scopus 로고    scopus 로고
    • Orthogonal self-assembly on colloidal gold-platinum nanorods
    • Martin, B. R. et al. Orthogonal self-assembly on colloidal gold-platinum nanorods. Adv. Matter. 11, 1021-1025 (1999).
    • (1999) Adv. Matter. , vol.11 , pp. 1021-1025
    • Martin, B.R.1
  • 79
    • 24544456587 scopus 로고    scopus 로고
    • Method of manufacture of colloidal rod particles as nanobar codes
    • WO Patent 01/25510
    • Martin, B. R. et al. Method of manufacture of colloidal rod particles as nanobar codes. WO Patent 01/25510 (2001).
    • (2001)
    • Martin, B.R.1
  • 80
    • 0035812821 scopus 로고    scopus 로고
    • Submicrometer metallic barcodes
    • Nicewarner-Peña, S. R. et al. Submicrometer metallic barcodes. Science 294, 137-141 (2001).
    • (2001) Science , vol.294 , pp. 137-141
    • Nicewarner-Peña, S.R.1
  • 81
    • 0242325879 scopus 로고    scopus 로고
    • A new generation of encoded microcarriers
    • Drug Discovery Technology 12-17 Aug 2001, Boston [online] (cited 01 May 02)
    • Braeckmans, K. et al. A new generation of encoded microcarriers. Drug Discovery Technology 12-17 Aug 2001, Boston [online] (cited 01 May 02) (2001).
    • (2001)
    • Braeckmans, K.1
  • 83
    • 0029763319 scopus 로고    scopus 로고
    • Line-scanning microphotolysis for diffraction-limited measurements of lateral diffusion
    • Wedekind, P., Kubitscheck, U., Heinrich, O. & Peters, R. Line-scanning microphotolysis for diffraction-limited measurements of lateral diffusion. Biophys. J. 71, 1621-1632 (1996).
    • (1996) Biophys. J. , vol.71 , pp. 1621-1632
    • Wedekind, P.1    Kubitscheck, U.2    Heinrich, O.3    Peters, R.4
  • 84
    • 0023677554 scopus 로고
    • Simultaneous detection of antibodies to cytomegalo-virus and herpes-simplex virus by using flow-cytometry and a microsphere-based fluorescence immunoassay
    • McHugh, T. M., Miner, R. C., Logan, L. H. & Stites, D. P. Simultaneous detection of antibodies to cytomegalo-virus and herpes-simplex virus by using flow-cytometry and a microsphere-based fluorescence immunoassay. J. Clin. Microbiol. 26, 1957-1961 (1988).
    • (1988) J. Clin. Microbiol. , vol.26 , pp. 1957-1961
    • McHugh, T.M.1    Miner, R.C.2    Logan, L.H.3    Stites, D.P.4
  • 85
    • 0024307594 scopus 로고
    • Early detection of antibodies against rDNA-produced HIV proteins with a flow cytometric assay
    • Scillian, J. J. et al. Early detection of antibodies against rDNA-produced HIV proteins with a flow cytometric assay. Blood 73, 2041-2048 (1989).
    • (1989) Blood , vol.73 , pp. 2041-2048
    • Scillian, J.J.1
  • 86
    • 4243966132 scopus 로고    scopus 로고
    • Encoding scheme for solid phase chemical libraries
    • WO Patent 00/61281
    • Geysen, M. Encoding scheme for solid phase chemical libraries. WO Patent 00/61281 (2000).
    • (2000)
    • Geysen, M.1
  • 87
    • 24544440861 scopus 로고    scopus 로고
    • Rapid screening assay methods and devices
    • US Patent 5,922,617
    • Wang, M. S. & Li, L. Rapid screening assay methods and devices. US Patent 5,922,617 (1999).
    • (1999)
    • Wang, M.S.1    Li, L.2
  • 88
    • 0034671868 scopus 로고    scopus 로고
    • Towards the DRED of resin-supported combinatorial libraries: A non-invasive methodology based on bead self-encoding and multispectral imaging
    • Fenniri, H. et al. Towards the DRED of resin-supported combinatorial libraries: a non-invasive methodology based on bead self-encoding and multispectral imaging. Angew. Chem. Int. Edn Engl. 37, 4483-4485 (2000).
    • (2000) Angew. Chem. Int. Edn Engl. , vol.37 , pp. 4483-4485
    • Fenniri, H.1
  • 89
    • 0034819777 scopus 로고    scopus 로고
    • Barcoded resins: A new concept for polymer-supported combinatorial library self-deconvolution
    • Fenniri, H., Ding, L. H., Ribbe, A. E. & Zyrianov, Y. Barcoded resins: a new concept for polymer-supported combinatorial library self-deconvolution. J. Am. Chem. Soc. 123, 8151-8152 (2001).
    • (2001) J. Am. Chem. Soc. , vol.123 , pp. 8151-8152
    • Fenniri, H.1    Ding, L.H.2    Ribbe, A.E.3    Zyrianov, Y.4
  • 90
    • 4243279313 scopus 로고    scopus 로고
    • Combinatorial chemical library supports having indicia at coding positions and methods of use
    • WO Patent 00/63419
    • Ravkin, I., Goldbard, S., Hyun, W. C. & Zarowitz, M. A. Combinatorial chemical library supports having indicia at coding positions and methods of use. WO Patent 00/63419 (2000).
    • (2000)
    • Ravkin, I.1    Goldbard, S.2    Hyun, W.C.3    Zarowitz, M.A.4
  • 91
    • 0032043853 scopus 로고    scopus 로고
    • Randomly ordered addressable high-density optical sensor arrays
    • Michael, K. L., Taylor, L. C. & Schultz, S. Randomly ordered addressable high-density optical sensor arrays. Anal. Chem. 70, 1242-1248 (1998).
    • (1998) Anal. Chem. , vol.70 , pp. 1242-1248
    • Michael, K.L.1    Taylor, L.C.2    Schultz, S.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.