Gingival eruption cysts induced by cyclosporine administration to neonatal dogs

Journal of Clinical Periodontology

Volumn 29, Issue 6, 2002, Pages 507-513

  O'Hara, Amanda J ^a   Collins, Teresa ^b   Howell, John McC ^a  

^a MURDOCH UNIVERSITY   (Australia)

^b UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

Author keywords

Cyclosporine adverse effects; Eruption cyst formation; Gingival overgrowth; Neonatal dog; Periodontium; Tooth eruption

Indexed keywords

CYCLOSPORIN; IMMUNOSUPPRESSIVE AGENT;

ADENOVIRUS; ANIMAL; ARTICLE; BLOOD; BODY WEIGHT; CANINE TOOTH; CHEMICALLY INDUCED DISORDER; COMPARATIVE STUDY; DISEASE MODEL; DOG; DRUG EFFECT; EPITHELIUM; FEMALE; GENE THERAPY; GENE VECTOR; GENETICS; GINGIVA DISEASE; GINGIVITIS; INCISOR; MALE; MESODERM; MOLAR TOOTH; MUSCULAR DYSTROPHY; NEUTROPHIL; NEWBORN; ODONTOGENIC CYST; PATHOLOGY; PREMOLAR TOOTH; REMISSION; TOOTH CROWN; TOOTH ERUPTION; TOOTH FLORA;

ADENOVIRIDAE; ANIMALS; ANIMALS, NEWBORN; BICUSPID; BODY WEIGHT; CUSPID; CYCLOSPORINE; DISEASE MODELS, ANIMAL; DOGS; ENAMEL ORGAN; EPITHELIUM; FEMALE; GENE THERAPY; GENETIC VECTORS; GINGIVAL DISEASES; GINGIVITIS; IMMUNOSUPPRESSIVE AGENTS; INCISOR; MALE; MESODERM; MOLAR; MUSCULAR DYSTROPHIES; NEUTROPHILS; ODONTOGENIC CYSTS; REMISSION INDUCTION; TOOTH CROWN; TOOTH ERUPTION;

EID: 0036598366     PISSN: 03036979     EISSN: None     Source Type: Journal    
DOI: 10.1034/j.1600-051X.2002.290606.x     Document Type: Article

References (20)

1. Dusci, L. J., Hackett, L. P., Chiswell, G. M. & Ilett, K. F. (1992) Comparison of cyclosporine measurement in whole blood by high-performance liquid chromatography, monoclonal fluorescence polarisation immunoassay, and monoclonal enzyme-multiplied immunoassay. Therapeutic Drug Monitoring 14, 327-332.
2. Dyce, K. M., Sack, W. O. & Wensing, C. J. G. (1987) Textbook of veterinary anatomy, p. 377. Philadelphia: W.B. Saunders.
3. Emmel, E. A., Verweij, C. L., Durand, D. B., Higgins, K. M., Lacy, E. & Crabtree, G. R. (1989) Cyclosporin A specifically inhibits function of nuclear proteins involved in T cell activation. Science 246, 1617-1620.
4. Hoffman, E., Brown, R. J. & Kunkel, L. M. (1987) Dystrophin: the protein product of the Duchenne muscular dystrophy locus. Cell 51, 919-928.
5. Howell, J., McC., Lochmüller, H., O'Hara, A., Fletcher, S., Kakulas, B. A., Massie, B., Nalbantoglu, J. & Karpati, G. (1998) High-level dystrophin expression after adenovirus-mediated dystrophin minigene transfer to skeletal muscle of dystrophic dogs: prolongation of expression with immunosuppression. Human Gene Therapy 9, 629-634.
6. Khanna, A., Li, B., Sharma, V. K. & Suthanthiran, M. (1996) Immunoregulatory and fibrogenic activities of cyclosporine: a unifying hypothesis based on transforming growth factor-beta expression. Transplantation Proceedings 28, 2015-2018.
7. Marks, S. C. Jr & Schroeder, H. E. (1996) Tooth eruption: theories and facts. Anatomical Record 245, 374-393.
8. Meraw, S. J. & Sheridan, P. J. (1998) Medically induced gingival hyperplasia. Mayo Clinical Proceedings 73, 1196-1199.
9. Myrillas, T. T., Linden, G. J., Marley, J. J. & Irwin, C. R. (1999) Cyclosporin A regulates interleukin-1beta and interleukin-6 expression in gingiva: implications for gingival overgrowth. Journal of Periodontology 70, 294-300.
10. Nares, S., Ng, M. C., Dill, R. E., Park, B., Cutler, C. W. & Iacopino, A. M. (1996) Cyclosporine A upregulates platelet-derived growth factor B chain in hyperplastic human gingiva. Journal of Periodontology 67, 271-278.
11. Nishikawa, S., Nagata, T., Morisaki, I., Oka, T. & Ishida, H. (1996) Pathogenesis of drug-induced gingival overgrowth. A review of studies in the rat model. Journal of Periodontology 67, 463-471.
12. Nomura, J., Tagawa, T., Seki, Y., Mori, A., Nakagawa, T. & Sugatani, T. (1996) Kinky hair disease with multiple eruption cysts: a case report. Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology and Endodontics 82, 537-540.
13. Rateitschak-Plüss, E. M., Hefti, A., Lortscher, R. & Thiel, G. (1983) Initial observation that cyclosporin-A induces gingival enlargement in man. Journal of Clinical Periodontology 10, 237-246.
14. Seibel, W., Yahia, N. A., McCleary, L. B., Lesko, L. J. & Hassell, T. M. (1989) Cyclosporine-induced gingival overgrowth in beagle dogs. Journal of Oral Pathology and Medicine 18, 240-245.
15. Seymour, R. A. (1993) Drug-induced gingival overgrowth. Adverse Drug Reaction and Toxicological Reviews 12, 215-232.
16. Soames, J. Y. & Southam, J. C. (1998) Oral pathology, 3rd edn, p. 73-81. Oxford: Oxford University Press Medical Publications.
17. Willershausen-Zonnchen, B., Lemmen, C. & Schumacher, U. (1992) Influence of cyclosporine A on growth and extracellular matrix synthesis of human fibroblasts. Journal of Cell Physiology 152, 397-402.
18. Wise, G. E. & Lin, F. (1995) The molecular biology of initiation of tooth eruption. Journal of Dental Research 74, 303-306.
19. Wise, G. E., Que, B. G. & Huang, H. (1999) Synthesis and secretion of MCP-1 by dental follicle cells - implications for tooth eruption. Journal of Dental Research 78, 1677-1681.
20. Yamada, H., Nishimura, F., Naruishi, K., Chou, H. H., Takashiba, S., Albright, G. M., Nares, S., Iacopino, A. M. & Murayama, Y. (2000) Phenytoin and cyclosporin A suppress the expression of MMP-1, TIMP-1, and cathepsin L, but not cathepsin B in cultured gingival fibroblasts. Journal of Periodontology 71, 955-960.