N(7)-substituted-5-aryl-pyrrolo[2,3-d]pyrimidines represent a versatile class of potent inhibitors of the tyrosine kinase c-Src.

Mini reviews in medicinal chemistry

Volumn 2, Issue 3, 2002, Pages 201-208

  Altmann, Eva ^a   Widler, Leo ^a   Missbach, Martin ^a  

^a NOVARTIS PHARMA AG   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN TYROSINE KINASE; PROTEIN TYROSINE KINASE C SRC; PROTEIN-TYROSINE KINASE C-SRC; PYRIMIDINE DERIVATIVE; PYRROLE DERIVATIVE; PYRROLO(2,3 D)PYRIMIDINE; PYRROLO(2,3-D)PYRIMIDINE;

ANIMAL; CHEMISTRY; DRUG ANTAGONISM; HUMAN; IC 50; OSTEOPOROSIS; REVIEW; STRUCTURE ACTIVITY RELATION;

ANIMALS; HUMANS; INHIBITORY CONCENTRATION 50; OSTEOPOROSIS; PROTEIN-TYROSINE KINASES; PYRIMIDINES; PYRROLES; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0036594795     PISSN: 13895575     EISSN: None     Source Type: Journal    
DOI: 10.2174/1389557023406188     Document Type: Review

References (20)