Effect of zeranol or melengestrol acetate (MGA) on testicular and antler development and aggression in farmed fallow bucks

Journal of Animal Science

Volumn 80, Issue 6, 2002, Pages 1433-1441

  Wilson, T W ^a,b   Neuendorff, D A ^a   Lewis, A W ^a   Randel, R D ^a,c  

^a TEXAS A AND M UNIVERSITY   (United States)

^b UNIVERSITY OF GEORGIA   (United States)

^c NONE   (United States)

Author keywords

Aggression; Fallow Deer; Melengestrol Acetate; Testosterone; Zeranol

Indexed keywords

CERVIDAE; CERVUS DAMA; CYNODON; GLYCINE MAX; LOLIUM; TILLETIACEAE; ZEA MAYS;

ESTROGEN; MELENGESTROL ACETATE; PROGESTERONE DERIVATIVE; TESTOSTERONE; ZERANOL;

AGGRESSION; ANIMAL; ANIMAL BEHAVIOR; ANIMAL DISEASE; ARTICLE; BLOOD; DEER; DRUG EFFECT; DRUG IMPLANT; GROWTH, DEVELOPMENT AND AGING; HISTOLOGY; HORN; MALE; ORGAN SIZE; PHYSIOLOGY; PSYCHOLOGICAL ASPECT; RANDOMIZATION; SCROTUM; SEXUAL MATURATION; SPERMATOZOON COUNT; TESTIS; WEIGHT GAIN;

AGGRESSION; ANIMALS; ANTLERS; BEHAVIOR, ANIMAL; DEER; DRUG IMPLANTS; ESTROGENS, NON-STEROIDAL; MALE; MELENGESTROL ACETATE; ORGAN SIZE; PROGESTERONE CONGENERS; RANDOM ALLOCATION; SCROTUM; SEXUAL MATURATION; SPERM COUNT; TESTIS; TESTOSTERONE; WEIGHT GAIN; ZERANOL;

EID: 0036593016     PISSN: 00218812     EISSN: None     Source Type: Journal    
DOI: 10.2527/2002.8061433x     Document Type: Article

References (30)

1. Amann, R. P. 1983. Endocrine changes associated with onset of spermatogenesis in holstein bulls. J. Dairy Sci. 66:2606-2622.
2. Asher, G. W. 1985. Reproduction of farmed fallow deer (Dama dama L.). In: Proc. of a Deer Course for Veterinarians, Ashburton, New Zealand. pp 107-123.
3. Asher, G. W., A. M. Day, and G. K. Barrell. 1987. Annual cycle of liveweight and reproductive changes of farmed male fallow deer (Dama dama) and the effect of daily oral administration of melatonin in summer on the attainment of seasonal fertility. J. Reprod. Fertil. 79:353-362.
4. Barrell, G. K., R. Daview, and C. I. Bailey. 1999. Immunocytochemical localization of oestrogen receptors in perichondrium of antlers in red deer (Cervus elaphus). Reprod. Fertil. Dev. 11:189-191.
5. Blaxter, K. L., R. N. B. Kay, G. A. M. Sharman, J. M. M. Cunningham, and W. J. Hamilton. 1974. Farming the Red Deer. Dept. of Agriculture and Fisheries, Her Majesty's Stationery Office, Edinburgh, U.K.
6. Blumer, E. S., E. D. Plotka, and W. B. Foxworth. 1992. Hormonal implants to control aggression in bachelor herds of scimitar horned oryx (Oryx dammah): a progress report. In: Proc. Joint Conf. Am. Assoc. of Zoo Vet. and Am. Assoc. of Wildlife Vet., Oakland, CA. pp 212-216.
7. Fraile, I. G., B. S. McEwen, and D. W. Pfaff. 1987. Progesterone inhibition of aggressive behaviors in hamsters. Physiol. Behav. 39(2):225-229.
8. Godfrey, R. W., D. D. Lunstra, T. G. Jenkins, J. G. Berardinelli, D. A. Neuendorff, C. R. Long, and R. D. Randel. 1990. Effect of location and season on body and testicular growth in Brahman and Hereford bulls. J. Anim. Sci. 68:1520-1529.
9. Godfrey, R. W., R. D. Randel, and F. M. Rouquette, Jr. 1989. Effect of zeranol on sexual development of crossbred bulls. J. Anim. Sci. 67:1751-1756.
10. Gravance, C. G., P. J. Casey, and M. J. Erpino. 1996. Progesterone does not inhibit aggression induced by testosterone metabolites in castrated male mice. Horm. Behav. 30:22-25.
11. Hogg, B. W., L. M. Catcheside, and G. J. K. Mercer. 1990. Carcass composition in male fallow deer: Age and castration effects and dissected tissue distribution. Anim. Prod. 51:405-413.
12. Johnson, M. H., and B. J. Everitt. 1995. The regulation of gonadal function. In: Essential Reproduction. 4th ed. pp 79-110. Blackwell Science Ltd., Cambridge, MA.
13. Juniewicz, P. E., T. H. Welsh, Jr., and B. H. Johnson. 1985. Effects of zeranol upon bovine testicular function. Theriogenology 23:565-582.
14. Lauderdale, J. W., L. S. Goyings, L. F. Krzeminski, and R. G. Zimbelman. 1977. Studies of a progestogen (MGA) as related to residues and human consumption. J. Toxicol. Environ. Health 3:5-33.
15. Lauderdale, J. W. 1983. Use of MGA (melengestrol acetate) in animal production. In: E. Meissonnier and J. Mitchell-Vigneron (ed.) Anabolics in Animal Production. Pp 193-212. Office International des Epizooties, Paris, France.
16. Lincoln, G. A. 1971. The seasonal reproductive changes in the Red deer stag. J. Zool. (Lond.) 163:105-123.
17. Lunstra, D. D., K. E. Gregory, and L. V. Cundiff. 1988. Heritability estimates and adjustment factors for the effects of bull age and age of dam on yearling testicular size in breeds of bulls. Theriogenology 30:127-136.
18. Patton, M. L., L. Aubrey, M. Edwards, R., Rieches, J. Zuba, and V. A. Lance. 2000. Successful contraception in a herd of Chinese goral (Nemorhaedus goral arnouxianus) with melengestrol acetate. J. Zool. Wildl. Med. 31:228-230.
19. Patton, M. L., A. M. White, R. R. Swaisgood, R. L. Sproul, G. A. Fetter, J. Kennedy, M. S. Edwards, R. G. Rieches, and V. A. Lance. 2001. Aggression control in a bachelor herd of fringe-eared oryx (Oryx gazella callotis), with melengestrol acetate: Behavioral and endocrine observations. Zoo Biol. 20:375-388.
20. Silcox, R. W., J. T. Keeton, and B. H. Johnson. 1986. Effects of zeranol and trenbolone acetate on testis function, live weight gain and carcass traits of bulls. J. Anim. Sci. 63:358-368.
21. Soares, M. J., W. D. Kalberer, and M. J. Erpino. 1977. Progestagen effects on elicitation of aggressive behaviour in male mice. J. Endocrinol. 73(3):507-510.
22. Staigmiller, R. B., R. M. Brownson, R. J. Kartchner, and J. H. Williams. 1985. Sexual development in beef bulls following zeranol implants. J. Anim. Sci. 60:342-351.
23. Stob, M., R. S. Baldwin, J. Tuite, F. M. Andrews, and K. G. Gillette. 1962. Isolation of an anabolic, uterotrophic compound from corn infected with Gibberella zeae. Nature (Lond.) 196:1318.
24. Stover, J., R. Warren, and P. Kalk. 1987. Effect of melengestrol acetate on male muntjac (Muntiacus reevesi). In: Proc. 1st Int. Conf. Zoological and Avian Med., Oahu, HI. pp 387-388.
25. Suttie, J. M. and P. F. Fennessy. 1992. Resent advances in the physiological control of velvet antler growth. In: R. Brown (ed.) Biology of Deer. Springer Verlag, New York.
26. Vera-Avila, H. R., T. D. A. Forbes, J. G. Berardinelli, and R. D. Randel. 1997. Effect of dietary phenolic amines on testicular function and luteinizing hormone secretion in male Angora goats. J. Anim. Sci. 75:1612-1620.
27. Webb, S. M., D. A. Neuendorff, A. W. Lewis, T. E. Adams, and R. D. Randel. 1999. Effect of zeranol implants and GnRH immunization on aggression, antler growth and testis function in yearling fallow bucks. J. Anim. Sci. 77(Suppl. 1):22 (Abstr.).
28. Willard, S. T. 1996. Factors influencing pregnancy status, seasonal reproduction and growth in farmed deer. Ph.D. dissertation. Texas A&M Univ., College Station.
29. Wilson, T. W., D. A. Neuendorff, and R. D. Randel. 1998. Alterations in antler and testis growth in fallow bucks implanted with zeranol as weanlings. J. Anim. Sci. 76(Suppl. 2):24 (Abstr.).
30. Wise, T. H. 1992. Developmental changes of serum thymosin alpha 1 and beta 4 in male and male castrated pigs: modulation by testosterone and human chorionic gonadotropin. Biol. Reprod. 46(5):892-897.