Olfactory functional testing: Sensitivity and specificity for Alzheimer's disease

Drug Development Research

Volumn 56, Issue 2, 2002, Pages 123-131

  Murphy, Claire ^a,b  

^a SAN DIEGO STATE UNIVERSITY   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Aging dementia; Alzheimer's disease; ApoE; Odor; Olfaction; Olfactory; Smell

Indexed keywords

ALZHEIMER DISEASE; DIAGNOSTIC ACCURACY; DIAGNOSTIC VALUE; DOWN SYNDROME; EVENT RELATED POTENTIAL; HUMAN; ODOR; OLFACTORY DISCRIMINATION; REVIEW; SMELLING;

EID: 0036592944     PISSN: 02724391     EISSN: None     Source Type: Journal    
DOI: 10.1002/ddr.10067     Document Type: Review

References (63)

1. Very early changes in olfactory functioning due to Alzheimer's disease and the role of Apolipoprotein E in olfaction
2. A test of odor fluency in patients with Alzheimer's and Huntington's disease
3. Neurofibrillary tangles, granulovacuolar degeneration and neuron loss in Down's syndrome: Quantitative comparison with Alzheimer's dementia
4. The development of the pathologic changes of Alzheimer's disease and senile dementia in patients with Down's syndrome
5. The association between quantitative measures of dementia and of senile change in gray matter of elderly subjects
6. The human entorhinal cortex: Normal morphology and lamina-specific pathology in various diseases
7. Frequency of stages of Alzheimer-related lesions in different age categories
8. Evaluation of olfactory dysfunction in the Connecticut Chemosensory Clinical Research Center
9. ERP indices and neuropsychological performance as predictors of functional outcome in dementia
10. Gene dose of apolipoprotein type 4 allele and the risk of Alzheimer's disease in late onset families
11. Rapid clinical evaluation of anosmia
12. Olfactory deficits in patients with mild cognitive impairment predict Alzheimer's disease at follow-up
13. Is the P300 component a manifestation of context updating?
14. Olfactory dysfunction in neurodegenerative disorders
15. Development of the University of Pennsylvania Smell Identification Test: A standardized microencapsulated test of olfactory function
16. The rhinologic evaluation of Alzheimer's disease
17. Psychological testing in the differential diagnosis of dementias
18. Profound loss of layer II entorbinal cortex neurons occurs in very mild Alzheimer's disease
19. Clinical utility of long latency "cognitive" event-related potentials (P3): The pros
20. Long latency event-related components of the auditory evoked potential in dementia
21. Olfactory identification deficits in Down's syndrome and idiopathic mental retardation
22. Alzheimer's disease, trisomy 21, and myeloproliferative disorders: Associations suggesting a genetic diathesis
23. Down syndrome and Alzheimer disease
24. The neuropathological diagnosis of Alzheimer's disease: Clinical-pathological studies
25. Pathologic changes in the olfactory system in aging and Alzheimer's disease
26. Alzheimer's disease
27. Olfactory tests as possible probes for detecting and monitoring Alzheimer's disease
28. Differences in olfactory test performance between normal aged. Alzheimer and vascular type dementia individuals
29. Olfactory evoked potentials in humans
30. Olfactory detection and recognition in Alzheimer's disease
31. The relationship between Down's Syndrome and dementia Alzheimer's type
32. A computer-controlled olfactometer for fMRI and electrophysiological studies of olfaction
33. Alzheimer's disease and Down's syndrome
34. Comparison of verbal fluency tasks in the detection of dementia of the Alzheimer type
35. Olfactory event-related potentials in Alzheimer's disease
36. Odor identification as an early marker for Alzheimer's disease: Impact of lexical functioning and detection sensitivity
37. Olfactory P3 in young and older adults
38. Olfactory dysfunction in Down's syndrome
39. Olfactory thresholds are associated with degree of dementia in Alzheimer's disease
40. Psychophysical assessment of chemosensory disorders in clinical populations
41. Apolipoprotein E status is associated with odor identification deficits in "normal" older persons
42. Olfactory event-related potentials and aging: Normative data
43. Apolipoprotein E immunoreactivity in cerebral amyloid deposits and neurofibrillary tangles in Alzheimer's disease and kuru plaque amyloid in Creutzfeldt-Jacob disease
44. Deficit in remote odor memory as measured by familiarity in Alzheimer's disease
45. Olfactory impairment as a function of age in persons with Down syndrome
46. Impaired sensory and cognitive olfactory function in questionable Alzheimer's disease
47. The scandinavian odor-identification test: Development, reliability, validity, and normative data
48. The locus for apolipoprotein E (apoE) is linked to the complement component C3 (C3) locus on chromosome 19 in man
49. Down's syndrome and Alzheimer's disease: A review
50. Mapping of event-related potentials to auditory and visual odd-ball paradigms in patients affected by different forms of dementia
51. Clinical application of the P3 component of event-related potentials. I. Normal aging
52. Clinical utility of long latency "cognitive" event-related potentials (P3): The cons
53. Apolipoprotein E polymorphism and Alzheimer's disease
54. The distribution of tangles, plaques and related immunohistochemical markers in healthy aging and Alzheimer's disease
55. Relationship between plaques, tangles, and dementia in Down's syndrome
56. Apolipoprotein E is a relevant susceptibility gene that affects the rate of expression of Alzheimer's disease
57. Taste, smell and neuropsychological performance of individuals at familial risk for Alzheimer's disease
58. Olfaction in dementia
59. Electrophysiological assessment of mental function in aging and dementia
60. Apolipoprotein E: High-avidity binding to beta-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease
61. Olfactory deficits and Down's syndrome
62. The performance of concurrent tasks: A psychophysiological analysis of the reciprocity of information processing resources
63. Occurrence of neuropathological changes and dementia of Alzheimer's disease in Down's syndrome