Immune effects due to exposure to low doses of inorganic mercury;Effetti immunitari da esposizione a basse dosi di mercurio inorganico

Medicina del Lavoro

Volumn 93, Issue 3, 2002, Pages 225-232

  Soleo, L ^a   Colosio, C ^b   Alinovi, R ^c   Guarneri, D ^d   Russo, A ^a   Lovreglio, P ^a   Vimercati, L ^a   Birindelli, S ^c   Cortesi, I ^e   Flore, C ^f   Carta, P ^f   Colombi, A ^g   Parrinello, G ^e   Ambrosi, L ^h  

^a POLICLINICO   (Italy)

^b Intl Centre for Pesticide Safety   (Italy)

^c UNIVERSITY OF PARMA   (Italy)

^d FATEBENEFRATELLI HOSPITAL   (Italy)

^e UNIVERSITY OF BRESCIA   (Italy)

^f UNIVERSITY OF CAGLIARI   (Italy)

^g UNIVERSITY OF MILAN   (Italy)

^h UNIVERSITY OF FOGGIA   (Italy)

Author keywords

IL 8; Immune system; Inorganic mercury; Very low doses

Indexed keywords

CD4 ANTIGEN; CD8 ANTIGEN; DENTAL ALLOY; INTERLEUKIN 8; MERCURY;

AUTOIMMUNITY; BLOOD LEVEL; CELLULAR IMMUNITY; CONFERENCE PAPER; DIETARY INTAKE; ENVIRONMENTAL EXPOSURE; FISH; HUMAN; HUMORAL IMMUNITY; HYPERSENSITIVITY; IMMUNE SYSTEM; LEUKOCYTE COUNT; NATURAL KILLER CELL; OCCUPATIONAL EXPOSURE; PROGNOSIS; TOXICITY TESTING;

ADULT; AIR POLLUTANTS, OCCUPATIONAL; ANIMALS; BIOLOGICAL MARKERS; CD4-CD8 RATIO; CHEMICAL INDUSTRY; DENTAL AMALGAM; DOSE-RESPONSE RELATIONSHIP, DRUG; ENVIRONMENTAL EXPOSURE; ENVIRONMENTAL POLLUTANTS; FEMALE; FISHES; FOOD CONTAMINATION; HUMANS; IMMUNE SYSTEM; INTERLEUKIN-8; KILLER CELLS, NATURAL; MALE; MAXIMUM ALLOWABLE CONCENTRATION; MERCURY; MIDDLE AGED; OCCUPATIONAL EXPOSURE; SEAFOOD; WATER POLLUTANTS, CHEMICAL;

EID: 0036591291     PISSN: 00257818     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Conference Paper

References (36)

1. ALESSIO L, APOSTOLI P, CORTESI I, LUCCHINI L: Introduzione: Scopi e finalità del progetto multicentrico "Valutazione degli effetti conseguenti a basse dosi di mercurio inorganico da esposizioni ambientali ed occupazionali: studio dei meccanismi di tossicità specifica in vitro e nell'uomo". Med Lav 2002; 93:148-156
2. AMERICAN CONFERENCE OF GOVERNMENTAL INDUSTRIAL HYGIENISTS: Threshold limit values (TLVs) for chemical substances and physical agents and biological exposure indices (BEIs). Cincinnati: ACGIH, 2000
3. BARCLAY AN, BIRKELAND ML, BROWN MH, et al (eds): The leucocyte antigens. London: Facts Book, Academic Press, 1993
4. BARKER JNWN, JONES ML, MITRA RS, et al: Modulation of keratinocite-derived interleukin-8 which is chemotactic for neutrophils and T lymphocytes. Am J Pathol 1991; 139: 869-876
5. BARR RD, REES PH, CORDY PE, et al: Nephrotic syndrome in adult Africans in Nairobi. Br Med J 1972; 2: 131-134
6. BARREGÅRD L, ENESTRÖM S, LJUNGHUSEN O, et al: A study of autoantibodies and circulating immune complexes in mercury-exposed chloralkali workers. Int Arch Occup Environ Health 1997; 70:101-106
7. BENCKO V, WAGNER V, WAGNEROVA M, ONDREJ ACK: Immunological profiles in workers occupationally exposed to inorganic mercury. J Hyg Epidemiol Microbiol 1990; 34: 9-15
8. BERNARD AM, ROELS HR, FOIDARD JM, LOUWERYS RL: Search for anti-laminin antibodies in the serum of workers exposed to cadmium, mercury vapour or lead. Int Arch Occup Environ Health 1987; 59: 303-309
9. CARDENAS A, ROELS H, BERNARD AM, et al: Markers of early renal changes induced by industrial pollutants. I. Application to workers exposed to mercury vapour. Br J Ind Med 1993; 50: 17-27
10. DANTAS DCM, QUEIROZ LS: Immunoglobulin E and autoantibodies in mercury-exposed workers. Immunopharmacol Immunotoxicol 1997; 19:383-392
11. DECARLI A, PARRINELLO G, CORTESI I, LUCCHINI R: Impiego di metodi regressivi nello studio della associazione fra differenti modalità di eposizione a mercurio e alcune variabili funzionali. Med Lav 2002; 93: 251-258
12. 2, in the Brown-Norway rat. Ann Immunol 1978; 129C: 777-792
13. DRUET P, PELLETIER R, ROSSERT J, et al: Autoimmune reactions induced by metals. In Kammuller ME, Bloksma N, Seinen W (eds): Autoimmunity and toxicology. Amsterdam: Elsevier, 1989: 347-361
14. ELLINGSEN DG, GAARDER PI, KJUUS H: An immunological study of chloralkali workers previously exposed to mercury vapour. APMIS 1994; 102: 170-176
15. ENESTRÖM S, HULTMAN P: Does amalgam affect the immune system? A controversial issue. Int Arch Allergy Immunol 1995; 106:180-203
16. FILLASTRE JP, DRUET P, MERY JP: Proteinuric nephropaties associated with drugs and substance of abuse. In: Cameron JS, Glassock RJ (eds): The nephropatic syndrome. New York: Wiley, 1988: 697-742
17. FRIBERG L, ENESTROM S: Toxicology of inorganic mercury. In Dayan AD, Hertel RF, Heseltine E, Kazantzis G, Smith EM, Van der Venne MT (eds): Immunotoxicity of metals and immunotoxicology. New York and London: Plenum Press, 1991: 163-173
18. HERRSTROM P, HOLMEN A, KARLSSON A, et al: Immune factors, dental amalgam, and low-dose exposure to mercury in Swedish adolescents. Arch Environ Health 1994; 49: 160-164
19. HOSTINAK JJ, HINZ RS, LORENCE CR, et al: Metals and skin. Crit Rev Toxicol 1993; 23: 171-235
20. HULTMAN P, ENESTROM S: The induction of immune complex deposits in mice by peroral and parenteral administration of mercuric chloride: strain dependent susceptibility. Clin Exp Immunol 1987; 67:283-292
21. HULTMAN P, ENESTROM S: Mercury induced antinuclear antibodies in mice: characterization and correlation with renal immune complex deposits. Clin Exp Immunol 1988; 71:269-274
22. LANGWORTH S, ELINDER CG, SUNDQVIST KG: Minor effects of low exposure to inorganic mercury on the immune system. Scand J Work Environ Health 1993; 19: 405-413
23. LAUWERYS R, BERNARD A, ROELS N, et al: Anti-laminin antibodies in workers exposed to mercury vapour. Toxicol Lett 1983; 17: 113-116
24. MAMMONE T, BIRINDELLI S, GUARNERI D, e coil: Adattamento del TriTEST TM per la raccolta di campioni ematici in studi multicentrici afferenti ad uno stesso laboratorio. Med Lav 2002; 93: 233-237
25. MESRI M, ALTIERI DC: Endothelial cell activation by leukocyte microparticles. J Immunol 1998; 161: 4382-4387
26. MOSZCZYNSKI P, SLOWINSKI S: The behaviour of T-cell subpopulations in the blood of workers exposed to mercury. Med Lav 1994; 85: 239-241
27. NICHOLSON TKA: Use of the flow citometry in the evaluation and diagnosis of primary and secondary immunodeficiency diseases. Arch Pathol Lab Med 1989; 113: 598-605
28. NORTH AMERICAN CONTACT DERMATITIS GROUP: Epidemiology of contact dermatitis in North America. Arch Dermatol 1972; 108: 537-540
29. + natural killer cells. Int Arch Occup Environ Health 2000; 73: 537-542
30. 2 induces non-specific immunosoppression in LEW rats. Eur J Immunol 1987; 17: 49-54
31. PELLETIER L, TOURNADE H, DRUET P: Immunologically mediated manifestations of metals. In Dayan AD, Hertel RF, Heseltine E, Kazantzis G, Smith EM, Van der Venne MT (eds): Immunotoxicity of metals and immunotoxicology. New York and London: Plenum Press, 1991: 121-138
32. ROGER J, ZILLIKENS D, HARTMANN AA, et al: Systemic autoimmune disease in a patient with long-standing exposure to mercury. Eur J Dermatol 1992; 2: 168-170
33. SCHRALLHAMMER-BENKLER K, RING J, PRZYBILLA B, et al: Acute mercury intoxication with lichenoid drug eruption followed by mercury contact allergy and development of antinuclear antibodies. Acta Derm Venereol (Stockh) 1992; 72: 294-296
34. SOLEO L, VACCA A, VIMERCATI L, et al: Minimal immunological effects on workers with prolonged low exposure to inorganic mercury. Occup Environ Med 1997;54:437-442
35. VIMERCATI L, SANTARELLI L, PESOLA G, et al: Monocyte-macrophage system and polymorphonuclear leukocytes in workers exposed to low levels of metallic mercury. Sci Tot Environ 2001; 270: 157-163
36. WORLD HEALTH ORGANIZATION: Inorganic mercury. Environmental Health Criteria n. 118. Geneva: WHO, 1991