Renal medullary interstitial infusion is a flawed technique for examining vasodilator mechanisms in anesthetized rabbits

Journal of Pharmacological and Toxicological Methods

Volumn 47, Issue 3, 2002, Pages 153-159

  Kalyan, Aparna ^a   Eppel, Gabriela A ^a   Anderson, Warwick P ^a   Oliver, Jeremy J ^a   Evans, Roger G ^a  

^a MONASH UNIVERSITY   (Australia)

Author keywords

Acetylcholine; Hypertension; Methods; Nitric oxide; Rabbits; Renal blood flow; Renal medulla; Vasodilatation

Indexed keywords

ACETYLCHOLINE; ADENOSINE; AMINE; BRADYKININ; METHYLAMINE HEXAMETHYLENE METHYLAMINE; PENTOBARBITAL; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; ARTIFICIAL VENTILATION; CATHETERIZATION; CONTROLLED STUDY; DOSE RESPONSE; DRUG DELIVERY SYSTEM; FEASIBILITY STUDY; INFUSION; INTERSTITIUM; KIDNEY BLOOD FLOW; KIDNEY CORTEX; KIDNEY MEDULLA; LASER DOPPLER FLOWMETRY; MALE; NONHUMAN; RABBIT; RENAL ARTERY; RENAL MEDULLARY INTERSTITIAL INFUSION; VASODILATATION;

ORYCTOLAGUS CUNICULUS;

EID: 0036589692     PISSN: 10568719     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1056-8719(02)00230-7     Document Type: Article

References (20)

1. 1 agonist on renal antihypertensive mechanisms in rabbits. American Journal of Physiology. 275:1998;R76-R85.
2. Carmines P.K. Angiotensin II regulation of the renal circulation. Anderson W.P., Evans R.G., Stevenson K.M. The renal circulation. 2000;191-205 JAI Press, Stamford, CT.
3. Correia A.G., Bergström G., Lawrence A.J., Evans R.G. Renal medullary interstitial infusion of norepinephrine: Methodological considerations. American Journal of Physiology. 277:1999;R112-R122.
4. Correia A.G., Madden A.C., Bergström G., Evans R.G. Effects of renal medullary and intravenous norepinephrine on renal antihypertensive function. Hypertension. 35:2000;965-970.
5. Cowley A.W. Jr. Role of the renal medulla in volume and arterial pressure regulation. American Journal of Physiology. 273:1997;R1-R15.
6. Cowley A.W. Jr., Mattson D.L., Lu S., Roman R.J. The renal medulla and hypertension. Hypertension. 25:1995;663-673.
7. 8] vasopressin on regional kidney perfusion and renal excretory function in anesthetized rabbits. Journal of Cardiovascular Pharmacology. 32:1998;571-581.
8. Evans R.G., Stevenson K.M., Bergström G., Denton K.M., Madden A.C., Gribben R.L., Weekes S.R., Anderson W.P. Sex differences in pressure diuresis/natriuresis in rabbits. Acta Physiologica Scandinavica. 169:2000;309-316.
9. Guild S.-J., Barrett C.J., Evans R.G., Malpas S.C. Interactions between neural and hormonal mediators of renal vascular tone in anaesthetized rabbits. Experimental Physiology. 2003;. (in press).
10. Guild S.-J., Eppel G.A., Malpas S.C., Rajapakse N.W., Stewart A., Evans R.G. Regional responsiveness of renal perfusion to activation of the renal nerves. American Journal of Physiology. 283:2002;R1177-R1186.
11. Harder D.R., Narayanan J., Birks E.K., Liard J.F., Imig J.D., Lombard J.H., Lange A.R., Roman R.J. Identification of a putative microvascular oxygen sensor. Circulation Research. 79:1996;54-61.
12. Kriz W. Structural organization of the renal medulla: Comparative and functional aspects. American Journal of Physiology. 241:1981;R3-R16.
13. Lu S., Mattson D.L., Cowley A.W. Jr. Renal medullary captopril delivery lowers blood pressure in spontaneously hypertensive rats. Hypertension. 23:1994;337-345.
14. Mattson D.L., Cowley A.W. Jr. Kinin actions on renal papillary blood flow and sodium excretion. Hypertension. 21:1993;961-965.
15. Mattson D.L., Lu S., Cowley A.W. Jr. Role of nitric oxide in the control of the renal medullary circulation. Clinical and Experimental Pharmacology and Physiology. 24:1997;587-590.
16. Mattson D.L., Lu S., Nakanishi K., Papanek P.E., Cowley A.W. Jr. Effect of chronic renal medullary nitric oxide inhibition on blood pressure. American Journal of Physiology. 266:1994;H1918-H1926.
17. Oliver J.J., Rajapakse N.W., Evans R.G. Effects of indomethacin on responses of regional kidney perfusion to vasoactive agents in rabbits. Clinical and Experimental Pharmacology and Physiology. 29:2002;873-879.
18. Rajapakse N.W., Oliver J.J., Evans R.G. Nitric oxide in responses of regional kidney blood flow to vasoactive agents in anesthetized rabbits. Journal of Cardiovascular Pharmacology. 40:2002;210-219.
19. Schnermann J. Tubuloglomerular feedback. Anderson W.P., Evans R.G., Stevenson K.M. The renal circulation. 2000;131-144 JAI Press, Stamford, CT.
20. Zou A.-P., Nithipatikom K., Li P.-L., Cowley A.W. Jr. Role of renal medullary adenosine in the control of blood flow and sodium excretion. American Journal of Physiology. 276:1999;R790-R798.