Polymorphism of the TT virus and its frequency in Polish blood donors

Vox Sanguinis

Volumn 82, Issue 4, 2002, Pages 177-181

  Grabarczyk, Piotr ^a   Brojer, E ^a  

^a INSTITUTE OF HEMATOLOGY AND TRANSFUSION MEDICINE   (Poland)

Author keywords

Blood donors; Genotypes; NC primers; ORF; Sequence analysis; TTV

Indexed keywords

VIRUS DNA;

ADULT; AGE; ARTICLE; BLOOD DONOR; DNA DETERMINATION; DONOR; GENE SEQUENCE; GENETIC POLYMORPHISM; GENOTYPE; HUMAN; MAJOR CLINICAL STUDY; NONHUMAN; NUCLEOTIDE SEQUENCE; POLAND; POLYMERASE CHAIN REACTION; PREVALENCE; PRIORITY JOURNAL; SEQUENCE HOMOLOGY; TORQUE TENO VIRUS; VIRUS DETECTION; VIRUS ISOLATION;

ADULT; AGE FACTORS; BLOOD DONORS; DNA PRIMERS; DNA VIRUS INFECTIONS; FALSE NEGATIVE REACTIONS; FEMALE; GENOTYPE; HUMANS; MALE; MIDDLE AGED; POLAND; POLYMERASE CHAIN REACTION; POLYMORPHISM, GENETIC; PREVALENCE; SENSITIVITY AND SPECIFICITY; SEQUENCE ANALYSIS, DNA; TORQUE TENO VIRUS;

EID: 0036588973     PISSN: 00429007     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1423-0410.2002.00178.x     Document Type: Article

References (19)

1. Nishizawa T, Okamoto H, Konishi K, Yoshizawa H, Miyakawa Y, Mayumi M: A novel DNA virus (TTV) associated with elevated transaminase levels in posttransfusion hepatitis of unknown aetiology. Biochem Biophys Res Commun 1997; 241:92-97
2. Charlton M, Adjei P, Poterucha J, Zein N, Moore B, Therneau T, Krom R, Wiesner R: TT-virus infection in North American blood donors, patients with fulminant hepatic failure, and cryptogenic cirrhosis. Hepatology 1998; 28:839-842
3. Gimenez-Barcons M, Forns X, Ampurdanes S, Guilera M, Soler M, Soguero C, Sanchez-Fueyo A, Mas A, Bruix J, Sanchez-Tapias JM, Rodes J, Saiz JC: Infection with a novel human DNA virus (TTV) has no pathogenic significance in patients with liver diseases. J Hepatol 1999; 30:1028-1034
4. Ho TF, Yang SC, Huang YT, Hsieh MH: TT virus infection in screened Taiwanese blood donors. Vox Sang 2000; 79:198-200
5. Hohne M, Berg T, Muller AR, Schreier E: Detection of sequences of TT virus, a novel DNA virus, in German patients. J Gen Virol 1998; 79:2761-2764
6. Nauomov NV, Petrova EP, Thomas MG, Williams R: Presence of a newly described human DNA virus (TTV) in patients with liver disease. Lancet 1998; 352:195-197
7. Prescott LE, Simmonds P, Path MRC: Global distribution of transfusion-transmitted virus. N Engl J Med 1998; 339:777
8. Safadi R, Ergunay K, Ilan Y, Klein A, Shouval D, Manny N, Harush N, Galun A: TT virus infection in Israeli patients with fulminant hepatic failure. Vox Sang 2000; 79:242-245
9. Simmonds P, Davidson F, Lycett C, Prescott LE, MacDonald DM, Ellender J, Yap PL, Ludlam CA, Haydon GH, Gillon J, Jarvis LM: Detection of a novel DNA virus (TTV) in blood donors and blood products. Lancet 1998; 352:191-194
10. Itoh K, Hirakawa K, Okamoto H, Ukita M, Tanaka H, Sawada N, Tsuda F, Miyakawa Y, Mayumi M: Infection by an unenveloped DNA virus associated with non-A-G hepatitis in Japanese blood donors with or without elevated ALT levels. Transfusion 1999; 39:522-526
11. Khudyakov YE, Cong M-E, Nichols B, Reed D, Dou X-G, Viazov SO, Chang J, Fried MW, Williams I, Bower W, Lambert S, Purdy M, Roggendorf M: Sequence heterogeneity of TT virus and closely related viruses. J Virol 2000; 74:2990-3000
12. Mushahwar I, Erker JC, Muerhoff AS, Leary TP, Simons JN, Birkenmeyer LG, Chalmers ML, Pilot-Matias TJ, Dexai SM: Molecular and biophysical characterisation of TT virus: Evidence for a new virus family infecting humans. Proc Natl Acad Sci USA 1999; 96:3177-3182
13. Okamoto H, Nishizawa T, Kato N, Ukita M, Ikeda H, Lizuka H, Miyakawa Y, Mayumi M: Molecular cloning and characterisation of a novel DNA virus (TTV) associated with posttransfusion hepatitis of unknown etiology. Hepatol Res 1998; 10:1-16
14. Okamoto H, Takahashi M, Nishizawa T, Ukita M, Fukuda M, Tsuda F, Miyakawa Y, Mayumi M: Marked genomic heterogeneity and frequent mixed infection of TT virus demonstrated by PCR with primers from coding and non coding regions. Virology 1999; 259:428-436
15. Takahashi K, Hoshino H, Ohta Y, Yoshida N, Mishiro S: Very high prevalence of Tr virus (TTV) infection in general population in Japan revealed by a new set of PCR primers. Hepatol Res 1998; 12:233-239
16. Simmonds P, Prescott LE, Logue C, Davidson F, Thomas AE, Ludlam CA: TT virus - Part of the normal human flora? J Infect Dis 1999; 180:1748-1749
17. Love A, Stanzeit B, Li L, Olafsdottir E, Gudmundsson S, Briem H, Widell A: Tr virus infections among blood donors in Iceland: Prevalence, genotypes, and lack of relationship to serum ALT levels. Transfusion 2000; 40:306-309
18. Saback FL, Gomes SA, de Paula VS, da Saliva RR, Lewis-Ximenez LL, Niel C: Age-specific prevalence and transmission of TTV virus. J Med Virol 1999; 59:318-322
19. Ball JK, Curran R, Beridge S, Grabowska AM, Jameson CL, Thomson BJ, Irving WL, Sharp PM: Tr virus sequence heterogeneity in vivo: Evidence for co-infection with multiple genetic types. J Gen Virol 1999; 80:1759-1768