Characterization of ceramides by low energy collisional-activated dissociation tandem mass spectrometry with negative-ion electrospray ionization

Journal of the American Society for Mass Spectrometry

Volumn 13, Issue 5, 2002, Pages 558-570

  Hsu, Fong Fu ^a   Turk, John ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COMPUTER AIDED DESIGN; FATTY ACIDS; IONIZATION; ISOMERS; MASS SPECTROMETRY; SPRAYING;

CERAMIDES;

CERAMIC MATERIALS;

ALCOHOL; ANION; CARBOXYETHYLAMINE; CARBOXYLIC ACID DERIVATIVE; CERAMIDE; DEUTERIUM; ETHYLAMINE; FATTY ACID; HYDROGEN; N ACYLAMINOETHANOL; UNCLASSIFIED DRUG; DYES, REAGENTS, INDICATORS, MARKERS AND BUFFERS; SPHINGOSINE;

MASS SPECTROMETRY;

ANALYTIC METHOD; ARTICLE; CHEMICAL BOND; DISSOCIATION; ELECTROSPRAY; FRAGMENTATION REACTION; ION EXCHANGE; IONIZATION; ISOMER; LIPID ANALYSIS; LOW ENERGY COLLISIONAL ACTIVATED DISSOCIATION TANDEM MASS SPECTROMETRY; REACTION ANALYSIS; STANDARD; STRUCTURE ANALYSIS; TANDEM MASS SPECTROMETRY; ANIMAL; BRAIN LEVEL; CATTLE; CHEMISTRY; ELECTROSPRAY MASS SPECTROMETRY; ISOTOPE LABELING;

ANIMALS; BRAIN CHEMISTRY; CATTLE; CERAMIDES; DEUTERIUM; INDICATORS AND REAGENTS; ISOTOPE LABELING; REFERENCE STANDARDS; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; SPHINGOSINE;

EID: 0036585050     PISSN: 10440305     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1044-0305(02)00358-6     Document Type: Article

References (13)

1. Hsu F. F.; Turk J.; Stewart M. E.; Downing D. T. Structural Studies on Ceramides as Lithiated Adducts by Low Energy Collisional-Activated Dissociation Tandem Mass Spectrometry with Electrospray Ionization. J. Am. Soc. Mass Spectrom., in press.
2. Gu M., Kerwin J.L., Watts J.D., Aebersold R. Ceramide Profiling of Complex Lipid Mixtures by Electrospray Ionization Mass Spectrometry. Anal. Biochem. 244:1997;347-356.
3. Raith K., Neubert R.H.H. Liquid Chromatography-Electrospray Mass Spectrometry and Tandem Mass Spectrometry of Ceramides. Anal. Chim. Acta. 403:2000;295-303.
4. Raith K., Neubert R.H.H. Structural Studies on Ceramides by Electrospray Tandem Mass Spectrometry. Rapid Commun. Mass Spectrom. 12:1998;935-938.
5. Vietzke J.P., Brandt O., Abeck D., Rapp C., Strassner M., Schreiner V., Hintze U. Comparative Investigation of Human Stratum Corneum Ceramides. Lipids. 36:2001;299-304.
6. Costello C.E., Vath J.E. McCloskey J.A. Methods in Enzymology. 1990;738-768 Academic Press, San Diego, CA. Vol. CXCIII.
7. + ions. J. Am. Soc. Mass Spectrom. 3:1992;260-263.
8. Ann Q., Adams J. Structural-Specific Collision-Induced Fragmentations of Ceramides Cationized with Alkali-Metal Ions. Anal. Chem. 65:1993;7-13.
9. Hsu F.F., Bohrer A., Turk J. Electrospray Ionization Tandem Mass Spectrometric Analysis of Sulfatide. Determination of Fragmentation Patterns and Characterization of Molecular Species Expressed in Brain and in Pancreatic Islets. Biochim. Biophys. Acta. 1392:(2-3):1998;202-216.
10. Hsu F.F., Turk J. Studies on Phosphatidylglycerol with Triple Quadrupole Tandem Mass Spectrometry with Electrospray Ionization Fragmentation Processes and Structural Characterization . J. Am. Soc. Mass Spectrom. 12:2001;1036-1043.
11. -, in Negative Ion Electrospray Ionization Mass Spectrometry. J. Am. Soc. Mass Spectrom. 11:2000;932-941.
12. Zhu J., Cole R.B. Ranking of Gas-Phase Acidities and Chloride Affinities of Monosaccharides and Linkage Specificity in Collision-Induced Decompositions of Negative Ion Electrospray-Generated Chloride Adducts of Oligosaccharides. J. Am. Soc. Mass Spectrom. 12:2001;1193-1204.
13. Harrison A.G. Chemical Ionization Mass Spectrometry. 1983;CRC Press, Florida. [chapter II].