Structural studies on C-amidated amino acids and peptides: Function of amide group in molecular association in crystal structures of Val-Gly-NH 2, Ser-Phe-NH2, Gly-Tyr-NH2 and Pro-Tyr-NH 2 hydrochloride salts

Chemical and Pharmaceutical Bulletin

Volumn 50, Issue 5, 2002, Pages 571-577

  In, Yasuko ^a   Ono, Hiroto ^a   Ishida, Toshimasa ^a  

^a OSAKA MEDICAL COLLEGE   (Japan)

Author keywords

C terminal amidation; Crystal structure; H Gly Tyr NH2; H Pro Tyr NH2; H Ser Phe NH2; H Val Gly NH2; Molecular conformation

Indexed keywords

AMIDE; AMINO ACID; CHLORIDE; CHLORIDE ION; GLYCYLTYROSINAMIDE; HYDROGEN; PEPTIDE DERIVATIVE; PROLYLTYROSINAMIDE; SERYLPHENYLANINAMIDE; UNCLASSIFIED DRUG; VALYLGLYCINAMIDE; OLIGOPEPTIDE;

AMIDATION; ARTICLE; CARBOXY TERMINAL SEQUENCE; CRYSTAL STRUCTURE; ENERGY; HYDROGEN BOND; PROTEIN CONFORMATION; PROTEIN STRUCTURE; X RAY ANALYSIS; X RAY DIFFRACTION; CHEMICAL STRUCTURE; CHEMISTRY; CONFORMATION; X RAY CRYSTALLOGRAPHY;

AMIDES; AMINO ACIDS; CRYSTALLOGRAPHY, X-RAY; HYDROGEN BONDING; MODELS, MOLECULAR; MOLECULAR CONFORMATION; OLIGOPEPTIDES;

EID: 0036583572     PISSN: 00092363     EISSN: 13475223     Source Type: Journal    
DOI: 10.1248/cpb.50.571     Document Type: Article

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