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3
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0033860837
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Heart failure in african americans: A cardiovascular enigma
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One of the first recent reviews of heart failure in black Americans
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Yancy CW: Heart failure in African Americans: a cardiovascular enigma. J Card Fail 2000, 6:183-186. One of the first recent reviews of heart failure in black Americans.
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Yancy, C.W.1
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4
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Racial differences in the outcome of left ventricular dysfunction [see comments] [published erratum appears in n engl j med 1999, 341:298]
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Dries DL, Exner DV, Gersh BJ, et al.: Racial differences in the outcome of left ventricular dysfunction [see comments] [published erratum appears in N Engl J Med 1999, 341:298]. N Engl J Med 1999, 340:609-616.
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Dries, D.L.1
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5
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0032836517
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Racial differences in response to therapy for heart failure: Analysis of the vasodilator-heart failure trials. Vasodilator-heart failure trial study group
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An important retrospective review of data from the vasodilator trials that raised the important question of a lack of responsiveness to ACEinhibitor therapy in black patients with heart failure
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Carson P, Ziesche S, Johnson G, et al.: Racial differences in response to therapy for heart failure: analysis of the vasodilator-heart failure trials. Vasodilator-Heart Failure Trial Study Group. J Card Fail 1999, 5:178-187. An important retrospective review of data from the vasodilator trials that raised the important question of a lack of responsiveness to ACEinhibitor therapy in black patients with heart failure.
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J Card Fail
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Carson, P.1
Ziesche, S.2
Johnson, G.3
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6
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0026092229
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Relation of left ventricular mass and geometry to morbidity and mortality in uncomplicated essential hypertension
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Natural history and patterns of current practice in heart failure. The studies of left ventricular dysfunction (solvd) investigators
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Bourassa MG, Gurne O, Bangdiwala SI, et al.: Natural history and patterns of current practice in heart failure. The Studies of Left Ventricular Dysfunction (SOLVD) Investigators. J Am Coll Cardiol 1993, 22:14A-19A.
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8
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0035978801
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A trial of the beta-blocker bucindolol in patients with advanced chronic heart failure
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The Beta-Blocker Evaluation of Survival Trial Investigators These data raised important concerns that the blacks within this large b-blocker trial not only didn't respond to b-blockers, but may have demonstrated excess mortality
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The Beta-Blocker Evaluation of Survival Trial Investigators: A trial of the beta-blocker bucindolol in patients with advanced chronic heart failure. N Engl J Med 2001, 344:1659-1667. These data raised important concerns that the blacks within this large b-blocker trial not only didn't respond to b-blockers, but may have demonstrated excess mortality.
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N Engl J Med
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9
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0035799777
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Lesser response to angiotensin-converting-enzyme inhibitor therapy in black as compared with white patients with left ventricular dysfunction
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This reanalysis of the SOLVD trials results suggested that the response to ACE-inhibitor therapy was less robust in blacks with heart failure
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Exner DV, Dries DL, Domanski MJ, et al.: Lesser response to angiotensin-converting-enzyme inhibitor therapy in black as compared with white patients with left ventricular dysfunction. N Engl J Med 2001, 344:1351-1357. This reanalysis of the SOLVD trials results suggested that the response to ACE-inhibitor therapy was less robust in blacks with heart failure.
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N Engl J Med
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Exner, D.V.1
Dries, D.L.2
Domanski, M.J.3
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10
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0035799754
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Race and the response to adrenergic blockade with carvedilol in patients with chronic heart failure
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These data demonstrated convincingly that the combination of carvedilol and ACE-inhibitors in mild to moderate heart failure is associated with similar outcomes in the black patient with heart failure. A subsequent analysis of the COPERNICUS database obtained from more severely ill patients with heart failure supported these findings
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Yancy CW, Fowler MB, Colucci WS, et al.: Race and the response to adrenergic blockade with carvedilol in patients with chronic heart failure. N Engl J Med 2001, 344:1358-1365. These data demonstrated convincingly that the combination of carvedilol and ACE-inhibitors in mild to moderate heart failure is associated with similar outcomes in the black patient with heart failure. A subsequent analysis of the COPERNICUS database obtained from more severely ill patients with heart failure supported these findings.
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N Engl J Med
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Yancy, C.W.1
Fowler, M.B.2
Colucci, W.S.3
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11
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Comparative effects of carvedilol and metoprolol on left ventricular ejection fraction in heart failure: Results of a meta-analysis
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Packer M, Antonopoulos GV, Berlin JA, et al.: Comparative effects of carvedilol and metoprolol on left ventricular ejection fraction in heart failure: results of a meta-analysis. Am Heart J 2001, 141:899-907.
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Am Heart J
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Packer, M.1
Antonopoulos, G.V.2
Berlin, J.A.3
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Effect of carvedilol on survival in severe chronic heart failure
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Packer M, Coats AJS, Fowler MB, et al.: Effect of carvedilol on survival in severe chronic heart failure. New Engl J Med 2001, 344:1651-1658.
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Packer, M.1
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Fowler, M.B.3
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Effect of carvedilol in black patients with severe heart failure: Results of the copernicus study [abstract]
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Carson P, Fowler MB, Mohacsi P, et al.: Effect of carvedilol in black patients with severe heart failure: results of the COPERNICUS Study [abstract]. Circulation 2001, 104:II-754.
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Carson, P.1
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Carvedilol, a new vasodilator and beta adrenoceptor antagonist, is an antioxidant and free radical scavenger
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Yue, T.L.1
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Challenges of subgroup analyses in multinational clinical trials: Experiences from the merit-hf trial
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Wedel H, Demets D, Deedwania P, et al.: Challenges of subgroup analyses in multinational clinical trials: experiences from the MERIT-HF trial. Am Heart J 2001, 142:502-511.
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Am Heart J
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Importance of the renin system in determining blood pressure fall with salt restriction in black and white hypertensives
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He FJ, Markandu ND, Sagnella GA, et al.: Importance of the renin system in determining blood pressure fall with salt restriction in black and white hypertensives. Hypertension 1998, 32:820-824.
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He, F.J.1
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0026592318
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The interaction of norepinephrine excretion with blood pressure and race in children
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Pratt JH, Manatunga AK, Bowsher RR, et al.: The interaction of norepinephrine excretion with blood pressure and race in children. J Hypertens 1992, 10:93-96.
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Racial differences in blood pressure control
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Plasma norepinephrine as a guide to prognosis in patients with chronic congestive heart failure
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A gain-of-function polymorphism in a g-protein coupling domain of the human beta1-adrenergic receptor
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Racial differences in the frequencies of cardiac beta(1)-adrenergic receptor polymorphisms: Analysis of c145a>g and c1165g>c
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Moore JD, Mason DA, Green SA, et al.: Racial differences in the frequencies of cardiac beta(1)-adrenergic receptor polymorphisms: analysis of c145AG and c1165GC. Hum Mutat 1999, 14:271.
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Cohn JN, Ferrari R, Sharpe N: Cardiac remodeling: concepts and clinical implications: a consensus paper from an international forum on cardiac remodeling. Behalf of an International Forum on Cardiac Remodeling. J Am Coll Cardiol 2000, 35:569-582.
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Transforming growth factor-beta1 hyperexpression in african-american hypertensives: A novel mediator of hypertension and/or target organ damage
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Suthanthiran M, Li B, Song JO, et al.: Transforming growth factor-beta1 hyperexpression in African-American hypertensives: a novel mediator of hypertension and/or target organ damage. Proc Natl Acad Sci U S A 2000, 97:3479-3484.
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Cardiac endothelin-1 plays a critical role in the functional deterioration of left ventricles during the transition from compensatory hypertrophy to congestive heart failure in salt-sensitive hypertensive rats
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These animal data come closest to establishing a plausible hypothesis for hypertension induced left ventricular dysfunction as may occur in black Americans
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Iwanaga Y, Kihara Y, Hasegawa K, et al.: Cardiac endothelin-1 plays a critical role in the functional deterioration of left ventricles during the transition from compensatory hypertrophy to congestive heart failure in salt-sensitive hypertensive rats. Circulation 1998, 98:2065-2073. These animal data come closest to establishing a plausible hypothesis for hypertension induced left ventricular dysfunction as may occur in black Americans.
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Iwanaga, Y.1
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