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1
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0026785561
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Effect of enalapril on mortality and the development of heart failure in asymptomatic patients with reduced left ventricular ejection fractions
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The SOLVD Investigators
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The SOLVD Investigators: Effect of enalapril on mortality and the development of heart failure in asymptomatic patients with reduced left ventricular ejection fractions. N Engl J Med 1992, 327:685-691.
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Effect of captopril on mortality and morbidity in patients with left ventricular dysfunction after myocardial infarction. Results of the survival and ventricular enlargement trial. The save investigators
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Pfeffer MA, Braunwald E, Moye LA, et al.: Effect of captopril on mortality and morbidity in patients with left ventricular dysfunction after myocardial infarction. Results of the survival and ventricular enlargement trial. The SAVE Investigators. N Engl J Med 1992, 327:669-677.
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Pfeffer, M.A.1
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0035100445
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The carvedilol prospective randomized cumulative survival (copernicus) trial
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Eichhorn EF, Bristow MR: The carvedilol prospective randomized cumulative survival (COPERNICUS) trial. Curr Control Trials Cardiovasc Med 2001, 2:20-23.
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0029089653
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Expression and functional significance of tumor necrosis factor receptors in human myocardium
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0029670957
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Tumor necrosis factor-alpha and tumor necrosis factor receptors in the failing human heart
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Torre-Amione G, Kapadia S, Lee J, et al.: Tumor necrosis factor-alpha and tumor necrosis factor receptors in the failing human heart. Circulation 1996, 93:704-711.
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Torre-Amione, G.1
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6
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0029871896
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Proinflammatory cytokine levels in patients with depressed left ventricular ejection fraction: A report from the studies of left ventricular dysfunction (solvd)
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Torre-Amione G, Kapadia S, Benedict C, et al.: Proinflammatory cytokine levels in patients with depressed left ventricular ejection fraction: a report from the Studies of Left Ventricular Dysfunction (SOLVD). J Am Coll Cardiol 1996, 27:1201-1206.
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Torre-Amione, G.1
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0033165556
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Results of a multidose phase i trial with tumor necrosis factor receptor (p75) fusion protein (entanercept) in patients with heart failure
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One of the first trials utilizing anti-TNF-a therapy in heart failure patients
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Bozkurt B, Torre-Amione G, Soram OZ, et al.: Results of a multidose phase I trial with tumor necrosis factor receptor (p75) fusion protein (Entanercept) in patients with heart failure. J Am Coll Cardiol 1999, 34:177-180. One of the first trials utilizing anti-TNF-a therapy in heart failure patients.
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Bozkurt, B.1
Torre-Amione, G.2
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0033614816
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Safety and efficacy of a soluble p75 tumor necrosis factor receptor (enbrel, etanercept) in patients with advanced heart failure
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Confirms safety of anti-TNF-a therapy in patients with heart failure
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Deswal A, Bozkurt B, Seta Y, et al.: Safety and efficacy of a soluble P75 tumor necrosis factor receptor (Enbrel, etanercept) in patients with advanced heart failure. Circulation 1999, 99:3224-3226. Confirms safety of anti-TNF-a therapy in patients with heart failure.
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Deswal, A.1
Bozkurt, B.2
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9
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0034831901
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Clinical trials update: Capricorn, copernicus, miracle, staf, ritz-2, recover and renaissance and cachexia and cholesterol in heart failure. Highlights of the scientific sessions of the american college of cardiology, 2001
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Summary and preliminary data on large-scale use of anti-TNF-a therapy
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Louis A, Cleland JG, Crabbe S, et al.: Clinical trials update: CAPRICORN, COPERNICUS, MIRACLE, STAF, RITZ-2, RECOVER and RENAISSANCE and cachexia and cholesterol in heart failure. Highlights of the Scientific Sessions of the American College of Cardiology, 2001. Eur J Heart Fail 2001, 3:381-387. Summary and preliminary data on large-scale use of anti-TNF-a therapy.
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Eur J Heart Fail
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Louis, A.1
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Crabbe, S.3
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10
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0033554456
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Decreased expression of tumor necrosis factor-alpha in failing human myocardium after mechanical circulatory support : A potential mechanism for cardiac recovery
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Original study in which authors demonstrate the importance of volume and pressure overload in TNF-a expression
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Torre-Amione G, Stetson SJ, Youker KA, et al.: Decreased expression of tumor necrosis factor-alpha in failing human myocardium after mechanical circulatory support : a potential mechanism for cardiac recovery. Circulation 1999, 100:1189-1193. Original study in which authors demonstrate the importance of volume and pressure overload in TNF-a expression.
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Torre-Amione, G.1
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0032515948
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Tumor necrosis factor-alpha confers resistance to hypoxic injury in the adult mammalian cardiac myocyte
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Nakano M, Knowlton AA, Dibbs Z, et al.: Tumor necrosis factor-alpha confers resistance to hypoxic injury in the adult mammalian cardiac myocyte. Circulation 1998, 97:1392-1400.
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Cardiac failure in transgenic mice with myocardial expression of tumor necrosis factor alpha
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Mechanisms of action of intravenous immune globulin in immune-mediated diseases
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14
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Controlled trial of intravenous immune globulin in recent-onset dilated cardiomyopathy
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Pivotal trial showing no added benefit for IVIG in patients with new onset cardiomyopathy
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McNamara DM, Holubkov R, Starling RC, et al.: Controlled trial of intravenous immune globulin in recent-onset dilated cardiomyopathy. Circulation 2001, 103:2254-2259. Pivotal trial showing no added benefit for IVIG in patients with new onset cardiomyopathy.
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McNamara, D.M.1
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15
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14344277564
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Immunomodulating therapy with intravenous immunoglobulin in patients with chronic heart failure
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Small trial showing benefit for prolonged administration of IVIG in patients with new-onset cardiomyopathy
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Gullestad L, Aass H, Fjeld JG, et al.: Immunomodulating therapy with intravenous immunoglobulin in patients with chronic heart failure. Circulation 2001, 103:220-225. Small trial showing benefit for prolonged administration of IVIG in patients with new-onset cardiomyopathy.
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Immunoglobulin adsorption in patients with idiopathic dilated cardiomyopathy
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Small trial showing benefit with immunoadsorption in patients with cardiomyopathy
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Muller J, Wallukat G, Dandel M, et al.: Immunoglobulin adsorption in patients with idiopathic dilated cardiomyopathy. Circulation 2000, 101:385-391. Small trial showing benefit with immunoadsorption in patients with cardiomyopathy.
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Muller, J.1
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The effects of vas972 therapy on allergic contact hypersensitivity
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Use of novel immunomodulating therapy in contact hypersensitivity
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Shivji GM, Suzuki H, Mandel AS, et al.: The effects of VAS972 therapy on allergic contact hypersensitivity. J Cutaneous Med Surg 2000, 4:132-137. Use of novel immunomodulating therapy in contact hypersensitivity.
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Role of transforming growth factor b-1 in the th1/th2 mechanisms of vasogen's immune modulation therapy: Potential role in psoriasis
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Freed I, Shahid S, Wang B, et al.: Role of transforming growth factor b-1 in the Th1/Th2 mechanisms of Vasogen's immune modulation therapy: potential role in psoriasis. J Invest Dermatol 2001, 117:388.
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Effect of oral milrinone on mortality in severe chronic heart failure: The promise study research group
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A dose-dependent increase in mortality with vesnarinone among patients with severe heart failure: Vesnarinone trial investigators
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Effect of flosequinan on survival in chronic heart failure: Preliminary results of the profile study [abstract]
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Beneficial effects of pimobendan on exercise tolerance and quality of life in patients with heart failure: Results of a multicenter trial
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Kubo SH, Gollub S, Bourge R, et al.: Beneficial effects of pimobendan on exercise tolerance and quality of life in patients with heart failure: results of a multicenter trial. Circulation 1992, 85:942-949.
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Kubo, S.H.1
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