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Volumn 4, Issue 3, 2002, Pages 226-232

Hypertrophic cardiomyopathy: Management issues in the new millennium

Author keywords

[No Author keywords available]

Indexed keywords

GENETIC PREDISPOSITION; GENETIC SCREENING; GENETICS; HUMAN; HYPERTROPHIC CARDIOMYOPATHY; ONSET AGE; PATHOPHYSIOLOGY; PREVALENCE; PROGNOSIS; REVIEW; RISK ASSESSMENT; RISK FACTOR; SUDDEN DEATH;

EID: 0036580926     PISSN: 15233782     EISSN: 15343170     Source Type: Journal    
DOI: 10.1007/s11886-002-0055-z     Document Type: Article
Times cited : (7)

References (44)
  • 1
    • 0029083650 scopus 로고
    • Prevalence of hypertrophic cardiomyopathy in a general population of young adults; echocardiographic analysis of 4111 subjects in the cardia study
    • Maron BJ, Gardin JM, Flack JM, et al.: Prevalence of hypertrophic cardiomyopathy in a general population of young adults; echocardiographic analysis of 4111 subjects in the CARDIA study. Circulation 1995, 92:785-789.
    • (1995) Circulation , vol.92 , pp. 785-789
    • Maron, B.J.1    Gardin, J.M.2    Flack, J.M.3
  • 2
    • 0019458147 scopus 로고
    • Prognosis in hypertrophic cardiomyopathy. Role of age and clinical, electrocardiographic and haemodynamic features
    • McKenna WJ, Deanfield J, Faruqui A, et al.: Prognosis in hypertrophic cardiomyopathy. Role of age and clinical, electrocardiographic and haemodynamic features. Am J Cardiol 1981, 47:532-538.
    • (1981) Am J Cardiol , vol.47 , pp. 532-538
    • McKenna, W.J.1    Deanfield, J.2    Faruqui, A.3
  • 3
    • 0022550266 scopus 로고
    • Intramural ("small vessel") coronary artery disease in hypertrophic cardiomyopathy
    • Maron BJ, Wolfson JK, Epstein SE, Roberts WC: Intramural ("small vessel") coronary artery disease in hypertrophic cardiomyopathy. J Am Coll Cardiol 1986, 8:545.
    • (1986) J Am Coll Cardiol , vol.8 , pp. 545
    • Maron, B.J.1    Wolfson, J.K.2    Epstein, S.E.3    Roberts, W.C.4
  • 4
    • 0030765610 scopus 로고    scopus 로고
    • Mutations in the cardiac troponin i gene associated with hypertrophic cardiomyopathy
    • Kimura A, Harada H, Park J-E, et al.: Mutations in the cardiac troponin I gene associated with hypertrophic cardiomyopathy. Nat Genet 1997, 16:379-382.
    • (1997) Nat Genet , vol.16 , pp. 379-382
    • Kimura, A.1    Harada, H.2    Park, J.-E.3
  • 5
    • 0024426784 scopus 로고
    • Mapping a gene for familial hypertrophic cardiomyopathy to chromosome 14q1
    • Jarcho JA, McKenna WJ, Pare JA, et al.: Mapping a gene for familial hypertrophic cardiomyopathy to chromosome 14q1. N Engl J Med 1989, 321:1372-1378.
    • (1989) N Engl J Med , vol.321 , pp. 1372-1378
    • Jarcho, J.A.1    McKenna, W.J.2    Pare, J.A.3
  • 6
    • 0027180678 scopus 로고
    • A familial hypertrophic cardiomyopathy locus maps to chromosome 15q2
    • Thierfelder L, MacRae C, Watkins H, et al.: A familial hypertrophic cardiomyopathy locus maps to chromosome 15q2. Proc Natl Acad Sci U S A 1993, 90:6270-6274.
    • (1993) Proc Natl Acad Sci U S A , vol.90 , pp. 6270-6274
    • Thierfelder, L.1    MacRae, C.2    Watkins, H.3
  • 7
    • 0027420155 scopus 로고
    • A disease locus for familial hypertrophic cardiomyopathy maps to chromosome 1q3
    • Watkins H, McRae C, Thierfelder L, et al.: A disease locus for familial hypertrophic cardiomyopathy maps to chromosome 1q3. Nat Genet 1993, 3:333-337.
    • (1993) Nat Genet , vol.3 , pp. 333-337
    • Watkins, H.1    McRae, C.2    Thierfelder, L.3
  • 8
    • 0028886136 scopus 로고
    • Cardiac myosin binding protein c gene splice acceptor site mutation is associated with familial hypertrophic cardiomyopathy
    • Bonne G, Carrier L, Bercovici J, et al.: Cardiac myosin binding protein C gene splice acceptor site mutation is associated with familial hypertrophic cardiomyopathy. Nat Genet 1995, 11:438-440.
    • (1995) Nat Genet , vol.11 , pp. 438-440
    • Bonne, G.1    Carrier, L.2    Bercovici, J.3
  • 9
    • 0026573969 scopus 로고
    • Characteristics and prognostic implications of myosin missense mutations in familial hypertrophic cardiomyopathy
    • Watkins H, Rozenzweig A, Hwang DS, et al.: Characteristics and prognostic implications of myosin missense mutations in familial hypertrophic cardiomyopathy. N Engl J Med 1992, 326:1108-1114.
    • (1992) N Engl J Med , vol.326 , pp. 1108-1114
    • Watkins, H.1    Rozenzweig, A.2    Hwang, D.S.3
  • 10
    • 15844400653 scopus 로고    scopus 로고
    • Mutations in either the essential or regulatory light chains of myosin are associated with a rare myopathy in human heart and skeletal muscle
    • Poetter K, Jiang H, Hassanzadeh S, et al.: Mutations in either the essential or regulatory light chains of myosin are associated with a rare myopathy in human heart and skeletal muscle. Nat Genet 1996, 13:63-69.
    • (1996) Nat Genet , vol.13 , pp. 63-69
    • Poetter, K.1    Jiang, H.2    Hassanzadeh, S.3
  • 11
    • 0033799445 scopus 로고    scopus 로고
    • Inherited and de novo mutations in the cardiac actin gene cause hypertrophic cardiomyopathy
    • Oslon TM, Doan TP, Kishimoto NY, et al.: Inherited and de novo mutations in the cardiac actin gene cause hypertrophic cardiomyopathy. J Mol Cell Cardiol 2000, 32:1687-1694.
    • (2000) J Mol Cell Cardiol , vol.32 , pp. 1687-1694
    • Oslon, T.M.1    Doan, T.P.2    Kishimoto, N.Y.3
  • 12
    • 0035872209 scopus 로고    scopus 로고
    • Mutations in the gamma (2) subunit of amp-activated protein kinase cause familial hcm: Evidence for the central role of energy compromise in disease pathogenesis
    • Blaire E, Redwood C, Ashrafian H, et al.: Mutations in the gamma (2) subunit of AMP-activated protein kinase cause familial HCM: evidence for the central role of energy compromise in disease pathogenesis. Hum Mol Genet 2001, 10:1215-1220.
    • (2001) Hum Mol Genet , vol.10 , pp. 1215-1220
    • Blaire, E.1    Redwood, C.2    Ashrafian, H.3
  • 13
    • 0029149023 scopus 로고
    • Angiotensin converting enzyme genotypes and left ventricular hypertrophy in patients with hypertrophic cardiomyopathy
    • Lechin M, Quinones MA, Omran A, et al.: Angiotensin converting enzyme genotypes and left ventricular hypertrophy in patients with hypertrophic cardiomyopathy. Circulation 1995, 92:1808-1812.
    • (1995) Circulation , vol.92 , pp. 1808-1812
    • Lechin, M.1    Quinones, M.A.2    Omran, A.3
  • 14
    • 0032580520 scopus 로고    scopus 로고
    • Mutations in the gene for cardiac-binding protein c and late onset familial hypertrophic cardiomyopathy
    • Niimura H, Bachinski LL, Sangwatanaroj S, et al.: Mutations in the gene for cardiac-binding protein C and late onset familial hypertrophic cardiomyopathy. N Eng J Med 1998, 338:1248-1257.
    • (1998) N Eng J Med , vol.338 , pp. 1248-1257
    • Niimura, H.1    Bachinski, L.L.2    Sangwatanaroj, S.3
  • 15
    • 0033540007 scopus 로고    scopus 로고
    • Late-onset hypertrophic cardiomyopathy caused by a mutation in the cardiac troponin t gene
    • Elliott PM, D'Cruz L, McKenna WJ: Late-onset hypertrophic cardiomyopathy caused by a mutation in the cardiac troponin T gene. N Engl J Med 1999, 341:1855-1856.
    • (1999) N Engl J Med , vol.341 , pp. 1855-1856
    • Elliott, P.M.1    D'Cruz, L.2    McKenna, W.J.3
  • 16
    • 0033858828 scopus 로고    scopus 로고
    • Utility of metabolic exercise testing in distinguishing hypertrophic cardiomyopathy from physiologic left ventricular hypertrophy in athletes
    • Sharma S, Elliott PM, Whyte G, et al.: Utility of metabolic exercise testing in distinguishing hypertrophic cardiomyopathy from physiologic left ventricular hypertrophy in athletes. J Am Coll Cardiol 2000, 36:864-870.
    • (2000) J Am Coll Cardiol , vol.36 , pp. 864-870
    • Sharma, S.1    Elliott, P.M.2    Whyte, G.3
  • 17
    • 0031052480 scopus 로고    scopus 로고
    • The management of hypertrophic cardiomyopathy
    • Nice review of the management of HCM
    • Spirito P, Seidman CE, McKenna WJ, Maron BJ: The management of hypertrophic cardiomyopathy. N Engl J Med 1997, 336:775-785. Nice review of the management of HCM.
    • (1997) N Engl J Med , vol.336 , pp. 775-785
    • Spirito, P.1    Seidman, C.E.2    McKenna, W.J.3    Maron, B.J.4
  • 18
    • 0022381296 scopus 로고
    • Verapamil induced improvement in left diastolic ventricular filling and increased exercise tolerance in patients with hypertrophic cardiomyopathy. Short and long term effects
    • Bonow RO, Dilsizian V, Rosing DR, et al.: Verapamil induced improvement in left diastolic ventricular filling and increased exercise tolerance in patients with hypertrophic cardiomyopathy. Short and long term effects. Circulation 1985, 72:853-864.
    • (1985) Circulation , vol.72 , pp. 853-864
    • Bonow, R.O.1    Dilsizian, V.2    Rosing, D.R.3
  • 19
    • 0030002289 scopus 로고    scopus 로고
    • Chest pain during daily life in patients with hypertrophic cardiomyopathy: An ambulatory electrocardiographic study
    • Elliott PM, Kaski JC, Prasad K, et al.: Chest pain during daily life in patients with hypertrophic cardiomyopathy: an ambulatory electrocardiographic study. Eur Heart J 1996, 17:1056-1064.
    • (1996) Eur Heart J , vol.17 , pp. 1056-1064
    • Elliott, P.M.1    Kaski, J.C.2    Prasad, K.3
  • 20
    • 0024284970 scopus 로고
    • Hypertrophic cardiomyopathy and sudden death
    • Nicod P, Polikar R, Peterson KL: Hypertrophic cardiomyopathy and sudden death. N Eng J Med 1988, 318:1255-1257.
    • (1988) N Eng J Med , vol.318 , pp. 1255-1257
    • Nicod, P.1    Polikar, R.2    Peterson, K.L.3
  • 21
    • 0025810220 scopus 로고
    • Myocardial metabolic, hemodynamic, and electrocardiographic significance of reversible thallium-201 abnormalities in hypertrophic cardiomyopathy
    • Cannon RO, Dilsizian V, O'Gara P, et al.: Myocardial metabolic, hemodynamic, and electrocardiographic significance of reversible thallium-201 abnormalities in hypertrophic cardiomyopathy. Circulation 1991, 83:1660.
    • (1991) Circulation , vol.83 , pp. 1660
    • Cannon, R.O.1    Dilsizian, V.2    O'Gara, P.3
  • 22
    • 0025829868 scopus 로고
    • Coronary vasodilatation is impaired in both hypertrophied and non hypertrophied myocardium of patients with hypertrophic cardiomyopathy: A study with nitrogen-13 ammonia and positron emission tomography
    • Camici P, Chiriatti G, Lorenzoni R, et al.: Coronary vasodilatation is impaired in both hypertrophied and non hypertrophied myocardium of patients with hypertrophic cardiomyopathy: a study with Nitrogen-13 ammonia and positron emission tomography. J Am Coll Cardiol 1991, 17:879-886.
    • (1991) J Am Coll Cardiol , vol.17 , pp. 879-886
    • Camici, P.1    Chiriatti, G.2    Lorenzoni, R.3
  • 23
    • 0017847498 scopus 로고
    • Long-term clinical course and symptomatic status of patients after operation for hypertrophic subaortic stenosis
    • Maron BJ, Merrill WH, Freier PA, et al.: Long-term clinical course and symptomatic status of patients after operation for hypertrophic subaortic stenosis. Circulation 1978, 57:1205-1213.
    • (1978) Circulation , vol.57 , pp. 1205-1213
    • Maron, B.J.1    Merrill, W.H.2    Freier, P.A.3
  • 24
    • 0023637204 scopus 로고
    • Results of surgery for hypertrophic obstructive cardiomyopathy
    • Williams WG, Wigle ED, Rakowski H, et al.: Results of surgery for hypertrophic obstructive cardiomyopathy. Circulation 1987, 76(Suppl V):V104-V108.
    • (1987) Circulation , vol.76 , Issue.SUPPL. V
    • Williams, W.G.1    Wigle, E.D.2    Rakowski, H.3
  • 25
    • 0029870435 scopus 로고    scopus 로고
    • Long-term results of left ventricular myotomy and myectomy for obstructive hypertrophic cardiomyopathy
    • Robbins RC, Stinson EB: Long-term results of left ventricular myotomy and myectomy for obstructive hypertrophic cardiomyopathy. J Thoac Cardiovas Surg 1996, 111:586-594.
    • (1996) J Thoac Cardiovas Surg , vol.111 , pp. 586-594
    • Robbins, R.C.1    Stinson, E.B.2
  • 26
    • 0029832010 scopus 로고    scopus 로고
    • Extent of clinical improvement after surgical treatment of hypertrophic obstructive cardiomyopathy
    • McCully RB, Nishimura RA, Tajik J, et al.: Extent of clinical improvement after surgical treatment of hypertrophic obstructive cardiomyopathy. Circulation 1996, 94:467-471.
    • (1996) Circulation , vol.94 , pp. 467-471
    • McCully, R.B.1    Nishimura, R.A.2    Tajik, J.3
  • 27
    • 0033558702 scopus 로고    scopus 로고
    • Perspectives on the role of new treatment strategies in hypertrophic obstructive cardiomyopathy
    • A nice review examining the therapeutic options available for the treatment of obstructive HCM
    • Spirito P, Maron B: Perspectives on the role of new treatment strategies in hypertrophic obstructive cardiomyopathy. J Am Coll Cardiol 1999, 33:1071-1075. A nice review examining the therapeutic options available for the treatment of obstructive HCM.
    • (1999) J Am Coll Cardiol , vol.33 , pp. 1071-1075
    • Spirito, P.1    Maron, B.2
  • 28
    • 0028650316 scopus 로고
    • Long-term results of dual chamber (ddd) pacing in obstructive hypertrophic cardiomyopathy. Evidence for progressive symptomatic and hemodynamic improvement and reduction of left ventricular hypertrophy
    • Fananapazir L, Epstein ND, Curiel RV, et al.: Long-term results of dual chamber (DDD) pacing in obstructive hypertrophic cardiomyopathy. Evidence for progressive symptomatic and hemodynamic improvement and reduction of left ventricular hypertrophy. Circulation 1994, 90:2731-2742.
    • (1994) Circulation , vol.90 , pp. 2731-2742
    • Fananapazir, L.1    Epstein, N.D.2    Curiel, R.V.3
  • 29
    • 0031036180 scopus 로고    scopus 로고
    • Dual chamber pacing for hypertrophic cardiomyopathy: A randomised double-blind crossover trial
    • Nishimura RA, Trusty JM, Hayes DL, et al.: Dual chamber pacing for hypertrophic cardiomyopathy: a randomised double-blind crossover trial. J Am Coll Cardiol 1997, 29:435-441.
    • (1997) J Am Coll Cardiol , vol.29 , pp. 435-441
    • Nishimura, R.A.1    Trusty, J.M.2    Hayes, D.L.3
  • 30
    • 8544240103 scopus 로고    scopus 로고
    • Pacing in hypertrophic obstructive cardiomyopathy. A randomised crossover study
    • (PIC study Group)
    • Kappenberger L, Linde C, Daubert C, et al., (PIC study Group): Pacing in hypertrophic obstructive cardiomyopathy. A randomised crossover study. Euro Heart J 1997, 18:1249-1256.
    • (1997) Euro Heart J , vol.18 , pp. 1249-1256
    • Kappenberger, L.1    Linde, C.2    Daubert, C.3
  • 31
    • 0029043605 scopus 로고
    • Non-surgical myocardial reduction for hypertrophy obstructive cardiomyopathy
    • Figwort U: Non-surgical myocardial reduction for hypertrophy obstructive cardiomyopathy. Lancet 1995, 346:211-214.
    • (1995) Lancet , vol.346 , pp. 211-214
    • Figwort, U.1
  • 32
    • 0030997143 scopus 로고    scopus 로고
    • Non-surgical reduction for hypertrophic obstructive cardiomyopathy: Outcome in the first series of patients
    • Knight C, Kurbaan AS, Seggewiss H, et al.: Non-surgical reduction for hypertrophic obstructive cardiomyopathy: outcome in the first series of patients. Circulation 1997, 95:2075-2081.
    • (1997) Circulation , vol.95 , pp. 2075-2081
    • Knight, C.1    Kurbaan, A.S.2    Seggewiss, H.3
  • 33
    • 84879226373 scopus 로고    scopus 로고
    • Abnormal blood pressure response during exercise is an independent marker of sudden death in young patients with hypertrophic cardiomyopathy
    • in press
    • Sadoul N, Prasad K, Slade AKB, et al.: Abnormal blood pressure response during exercise is an independent marker of sudden death in young patients with hypertrophic cardiomyopathy. Circulation 1997, in press.
    • (1997) Circulation
    • Sadoul, N.1    Prasad, K.2    Slade, A.K.B.3
  • 34
    • 0025676652 scopus 로고
    • Abnormal blood pressure response during exercise in hypertrophic cardiomyopathy
    • Frenneaux MP, Counihan PJ, Caforio A, et al.: Abnormal blood pressure response during exercise in hypertrophic cardiomyopathy. Circulation 1990, 82:1995-2002.
    • (1990) Circulation , vol.82 , pp. 1995-2002
    • Frenneaux, M.P.1    Counihan, P.J.2    Caforio, A.3
  • 35
    • 0025822693 scopus 로고
    • Abnormal vascular responses to supine exercise in hypertrophic cardiomyopathy
    • Counihan PJ, Frenneaux MP, Webb DJ, McKenna WJ: Abnormal vascular responses to supine exercise in hypertrophic cardiomyopathy. Circulation 1991, 84:686-696.
    • (1991) Circulation , vol.84 , pp. 686-696
    • Counihan, P.J.1    Frenneaux, M.P.2    Webb, D.J.3    McKenna, W.J.4
  • 36
    • 0034660438 scopus 로고    scopus 로고
    • Magnitude of left ventricular hypertrophy and risk of sudden death in hypertrophic cardiomyopathy
    • This article demonstrates that extreme left ventricular hypertrophy is associated with an increased risk of sudden death
    • Spirito P, Bellone P, Harris KM, et al.: Magnitude of left ventricular hypertrophy and risk of sudden death in hypertrophic cardiomyopathy. N Engl J Med 2000, 342:1778-1785. This article demonstrates that extreme left ventricular hypertrophy is associated with an increased risk of sudden death.
    • (2000) N Engl J Med , vol.342 , pp. 1778-1785
    • Spirito, P.1    Bellone, P.2    Harris, K.M.3
  • 37
    • 0037864392 scopus 로고    scopus 로고
    • Relation between severity of lvh and prognosis in patients with hypertrophic cardiomyopathy
    • This article demonstrates that although a wall thickness of 30 mm or more in combination with other risk factors does increase the likelihood of sudden death, the presence of mild hypertrophy cannot be used to reassure individuals
    • Elliott PM, Gimeno Blanes JR, et al.: Relation between severity of LVH and prognosis in patients with hypertrophic cardiomyopathy. Lancet 2001, 357:407-408. This article demonstrates that although a wall thickness of 30 mm or more in combination with other risk factors does increase the likelihood of sudden death, the presence of mild hypertrophy cannot be used to reassure individuals.
    • (2001) Lancet , vol.357 , pp. 407-408
    • Elliott, P.M.1    Gimeno Blanes, J.R.2
  • 38
    • 0033667442 scopus 로고    scopus 로고
    • Sudden death in hypertrophic cardiomyopathy: Identification of high-risk patients
    • This article demonstrates that patients at increased risk of sudden death can readily be detected using noninvasive techniques. Management strategies can then be determined based on the presence of risk markers
    • Elliott PM, Poloniecki J, Dickie S, et al.: Sudden death in hypertrophic cardiomyopathy: identification of high-risk patients. J Am Coll Cardiol 2000, 36:2212-2218. This article demonstrates that patients at increased risk of sudden death can readily be detected using noninvasive techniques. Management strategies can then be determined based on the presence of risk markers.
    • (2000) J Am Coll Cardiol , vol.36 , pp. 2212-2218
    • Elliott, P.M.1    Poloniecki, J.2    Dickie, S.3
  • 39
    • 0021811221 scopus 로고
    • Improved survival with amiodarone in patients with hypertrophic cardiomyopathy and ventricular tachycardia
    • McKenna WJ, Oakley CM, Krikler DM, et al.: Improved survival with amiodarone in patients with hypertrophic cardiomyopathy and ventricular tachycardia. Br Heart J 1985, 53:412-416.
    • (1985) Br Heart J , vol.53 , pp. 412-416
    • McKenna, W.J.1    Oakley, C.M.2    Krikler, D.M.3
  • 40
    • 0037603009 scopus 로고    scopus 로고
    • Amiodarone and sudden death in hypertrophic cardiomyopathy [abstract]
    • in press
    • Elliott PM, Sharma S, Poloniecki J, et al.: Amiodarone and sudden death in hypertrophic cardiomyopathy [abstract]. Circulation 1997, in press.
    • (1997) Circulation
    • Elliott, P.M.1    Sharma, S.2    Poloniecki, J.3
  • 41
    • 0034628532 scopus 로고    scopus 로고
    • Efficacy of implantable cardioverter-defibrillators for the prevention of sudden death in patients with hypertrophic cardiomyopathy
    • The effectiveness of the implantable defibrillator in terminating ventricular arrhythmias in hypertrophic cardiomyopathy is demonstrated in this article
    • Maron BJ, Shen WK, Link MS, et al.: Efficacy of implantable cardioverter-defibrillators for the prevention of sudden death in patients with hypertrophic cardiomyopathy. N Engl J Med 2000, 342:365-373. The effectiveness of the implantable defibrillator in terminating ventricular arrhythmias in hypertrophic cardiomyopathy is demonstrated in this article.
    • (2000) N Engl J Med , vol.342 , pp. 365-373
    • Maron, B.J.1    Shen, W.K.2    Link, M.S.3
  • 42
    • 0032053714 scopus 로고    scopus 로고
    • Hypertrophic cardiomyopathy: Role of the implantable cardioverter defibrillator
    • Primo J, Geelen P, Brugada J, et al.: Hypertrophic cardiomyopathy: role of the implantable cardioverter defibrillator. J Am Coll Cardiol 1998, 31:1081-1085.
    • (1998) J Am Coll Cardiol , vol.31 , pp. 1081-1085
    • Primo, J.1    Geelen, P.2    Brugada, J.3
  • 43
    • 0027528936 scopus 로고
    • Sudden cardiac death and the use of implantable cardioverter- defibrillator in paediatric patients
    • Silka MJ, Kron J, Dunnigan A, Dick M: Sudden cardiac death and the use of implantable cardioverter-defibrillator in paediatric patients. Circulation 1993, 87:800-807.
    • (1993) Circulation , vol.87 , pp. 800-807
    • Silka, M.J.1    Kron, J.2    Dunnigan, A.3    Dick, M.4
  • 44
    • 0025147726 scopus 로고
    • The automatic implantable cardioverter defibrillator in young patients
    • Kron J, Oliver RP, Norsted S, Silka MJ: The automatic implantable cardioverter defibrillator in young patients. J Am Coll Cardiol 1990, 16:896-902.
    • (1990) J Am Coll Cardiol , vol.16 , pp. 896-902
    • Kron, J.1    Oliver, R.P.2    Norsted, S.3    Silka, M.J.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.