Hypoglycemic effect of a lentinus edodes exo-polymer producedfrom a submerged mycelial culture

Bioscience, Biotechnology and Biochemistry

Volumn 66, Issue 5, 2002, Pages 937-942

  Yang, Byung Keun ^a   Kim, Dong Hyun ^a   Jeong, Sang Chul ^a   Das, Surajit ^a   Choi, Young Sun ^a   Shin, Joon Shik ^a   Lee, Sang Chul ^a   Song, Chi Hyun ^a  

^a Daegu University   (South Korea)

Author keywords

Exo polymer; Hypoglycemic effect; Lentinus edodes; Submerged mycelial culture

Indexed keywords

ALANINE AMINOTRANSFERASE; ANTIDIABETIC AGENT; ASPARTATE AMINOTRANSFERASE; BIOPOLYMER; STREPTOZOCIN;

ANIMAL; ARTICLE; BLOOD; BODY WEIGHT; CHEMISTRY; DRUG EFFECT; EXPERIMENTAL DIABETES MELLITUS; FEEDING BEHAVIOR; GEL CHROMATOGRAPHY; GLUCOSE BLOOD LEVEL; ISOLATION AND PURIFICATION; LENTINUS EDODES; MALE; ORAL DRUG ADMINISTRATION; RAT; SPRAGUE DAWLEY RAT;

ADMINISTRATION, ORAL; ALANINE TRANSAMINASE; ANIMALS; ASPARTATE AMINOTRANSFERASES; BIOPOLYMERS; BLOOD GLUCOSE; BODY WEIGHT; CHROMATOGRAPHY, GEL; DIABETES MELLITUS, EXPERIMENTAL; FEEDING BEHAVIOR; HYPOGLYCEMIC AGENTS; MALE; RATS; RATS, SPRAGUE-DAWLEY; SHIITAKE MUSHROOMS; STREPTOZOCIN;

BASIDIOMYCOTA; LENTINULA EDODES; LENTINUS;

EID: 0036562437     PISSN: 09168451     EISSN: 13476947     Source Type: Journal    
DOI: 10.1271/bbb.66.937     Document Type: Article

References (35)

1. Chihara, G., Maeda, Y., Hamuro, J., Sasaki, T., and Fukuoka, F., Inhibition of mouse sarcoma 180 by polysaccharides from Lentinus edodes (Berk.) sing. Nature, 17, 687-688 (1969).
2. Kabir, Y., Yamaguchi, M., and Kimura, S., Effect of Shiitake (Lentinus edodes) and Maitake (Grifola frondosa) mushrooms on blood pressure and plasma lipids of spontaneously hypertensive rats. J. Nutr. Sci. Vitaminol., 33, 341-346 (1987).
3. Kaneda, T., and Tokuda, S., Effect of various mushroom preparations on cholesterol levels in rats. J. Nutr. Rep. Int., 26, 167-173 (1966).
4. Jeong, H., Lee, J. W., and Lee, K. H., Studies on the anti-complementary activity of Korean higher fungi. Kor. J. Mycol., 18, 145-148 (1990).
5. Lee, J. W., Chung, C. H., Jeong, H., and Lee, K. H., Anticomplementary and antitumor activities of the alkali extract from the mycelia of Lentinus edodes IY 105. Kor. J. Appl. Microbiol. Biotechnol., 6, 571-577 (1990).
6. Kim, M. Y., Park, M. H., and Kim, G. H., Effects of mushroom protein-bound polysaccharides on the blood glucose levels and energy metabolism in streptozotocin-induced diabetic rats. J. Kor. Nutr., 30, 743-750 (1997).
7. Kiho, T., Sobue, S., and Ukai, S., Structural features and hypoglycemic activities of two polysaccharides from a hot-water extract of Agrocybe cylindracea. Carbohydr. Res., 251, 81-87 (1994).
8. Kiho, T., Morimoto, H., Sakushima, M., Usui, S., and Ukai, S., Polysaccharide in fungi, XXXV. Antidiabetic activity of an acidic polysaccharide from the fruiting bodies of Tremella aurantia. Biol. Pharm. Bull., 18, 1627-1629 (1995).
9. Kiho, T., Yamane, A., Hui, J., Usui, S., and Ukai, S., Polysaccharide in fungi, XXXVI. Hypoglycemic activity of a polysaccharide (CS-F30) from the cultural mycelium Cordyceps sinensis and its effect on glucose metabolism in mouse liver. Biol. Pharm. Bull., 19, 294-296 (1996).
10. Kiho, T., Itahashi, S., Sakushima, M., Matsunaga, T., Usui, S., Ukai, S., Mori, H., Sakamoto, H., and Ishiguro, Y., Polysaccharide in fungi. XXXVIII. Anti-diabetic activity and structural features of galac-tomannan elaborated by Pestalotiopsis species. Biol. Pharm. Bull., 20, 118-121 (1997).
11. Hikino, H., Ishiyama, M., Suzuki, Y., and Konno, C., Mechanisms of hypoglycemic activity of Ganode-ran B: A glycan of Ganoderma lucidum fruit bodies. Planta Medica, 55, 423-428 (1989).
12. Yuan, Z. M., He, P. M., Cui J. H., and Takeuchi, H., Hypoglycemic effect of water-soluble polysaccharide from Auricularia auricula-judae Quel. on genetic diabetic KK-Ay mice. Biosci. Biotechnol. Biochem., 62, 1898-1903 (1998).
13. Cavazzoni, V., and Adami, A., Exopolysaccharides produced by mycelial edible mushrooms. Ital. J. Food Sci., 1, 9-15 (1992).
14. Jong, S. C., and Birmingham, J. M., Medicinal benefits of the mushroom Ganaderma. Adv. Appl. Microbiol., 37, 101-134 (1992).
15. Tseng, T. C., Studies on Ganoderma lucidum 1. Liquid culture and chemical composition of mycelium. Bot. Bull. Axad. Sin. (Taipei)., 25, 149-154 (1984).
16. from culture medium of Lentinus edodes mycelia. Cancer Lett., 27, 1-6(1985).
17. of replication and of the cytopathic effect of human immunodeficiency virus by an extract of the culture medium of Lentinus edodes mycelia. Med. Microbiol. Immunol. (Berl)., 177, 235-44 (1988).
18. Suzuki, H., Iiyama, K., Yoshida, O., Yamazaki, S., Yamamoto, N., and Toda, S., Structural characterization of the immunoactive and antiviral water-solubilized lignin in an extract of the culture medium of Lentinus edodes mycelia (LEM). Agric. Biol. Chem., 54, 479-87 (1990).
19. Tabata, T., Watanabe, W., Horita, K., Kamegai, J., Moriyama, S., Hibino, Y., Ohashi, Y., and Sugano, N., Mitogenic activities of heteroglycan and heter-oglycan-protein fractions from culture medium of Lentinus edodes mycelia. Immunopharmacology, 24, 57-63 (1992).
20. Yamamoto, Y., Shirono, H., Kono, K., and Ohashi, Y., Immunopotentiating activity of the water-soluble lignin rich fraction prepared from LEM--the extract of the solid culture medium of Lentinus edodes mycelia. Biosci. Biotechnol. Biochem. 61, 1909-1912 (1997).
21. Lowry, O. H., Rosebrough, N. J., Farr, L., and Randall, R. J. Protein measurement with the Folin phenol reagent. J. Biol. Chem., 193, 265-275 (1951).
22. Waters Associates: Official method of amino acid analysis. Amino acid analysis system in the operation manual of Waters Associates, U.S.A., p. 37 (1980).
23. Dubois, M., Gilles, K. A., Hamilton, J. K., Rebers, P. A., and Smith, F. Colorimetric method for determination of sugar and related substance. Analyt. Chem., 28, 350-356 (1956).
24. Jones, T. M., and Albersheim, P. O. A gas chromatography method for the determination of aldose and uronic acid constituents of plant cell wall polysaccharide. Plant Physiol., 49, 926-936 (1972).
25. Duncan, D. M. Multiple-range tests for correlated and heteroscedastic means. Biometrics, 13, 164-170 (1957).
26. Furuse, M., Kimura, C., Mabayo, R. T., Takahashi, H., and Okumara, J., Dietary sorbose prevents and improves hyperglycemia in genetically diabetic mice. J. Nutr., 123, 59-65 (1993).
27. Mendola, J., Wright, J. R., and Lacy, P. E., Oxygen free radical scavenger and immune destruction of murine low-dose STZ-induced insulitis. Diabetes, 38, 379-385 (1989).
28. 2 generation and DNA fragmentation in pancreatic islets. Diabetes, 40, 1141-1145 (1991).
29. Gray, A. M., and Flatt, P. R., Insulin-releasing and insulin-like activity of Agaricus campestris(mushroom). J. Endocrinol., 157, 259-266 (1998).
30. Baron, H, and Roheim, P. S., Hyperlipidemia in streptozotocin-treated rats. Diabetes, 25, 509-515 (1976).
31. Hayes, T. M., Plasma lipoproteins in adult diabetes. Clin. Endocrinol., 1, 247-251 (1972).
32. Bierman, E. L., George Lyman Duff MemorialLecture. Atherogenesis in diabetes. ArteriosclerosisThromb., 12, 647-656 (1992).
33. Garg, A., and Grundy, S. M., Management of dys-lipidemia in NIDDM. Diabetes Care, 13, 153-169 (1990).
34. 4 and bromobenzen. Klin. Wochenschr., 64 (Suppl. 7), 47-50 (1986).
35. Van Horn, L. V., Lipid metabolism and choices for persons with diabetes. In “Hand Book of Diabetes Medical Nutrition Therapy,” ed. Powers M. A., Aspen Publishers, Inc. Gaithersburg, Maryland, pp. 336-359 (1996).