Serum Keratan sulphate as a cartilage metabolic marker in horses: The effect of exercise

Journal of Veterinary Medicine Series A: Physiology Pathology Clinical Medicine

Volumn 49, Issue 4, 2002, Pages 195-197

  Okumura, M ^a   Kim, G H ^a   Tagami, M ^a,b   Haramaki, S ^a,b   Fujinaga, T ^a  

^a HOKKAIDO UNIVERSITY   (Japan)

^b Shadai Horse Clinic   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MARKER; KERATAN SULFATE;

AGE; ANIMAL; ANIMAL DISEASE; ANIMAL EXPERIMENT; ARTICLE; ARTICULAR CARTILAGE; BLOOD; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; HORSE; MALE; METABOLISM; METHODOLOGY; PHYSIOLOGY;

AGE FACTORS; ANIMALS; BIOLOGICAL MARKERS; CARTILAGE, ARTICULAR; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; HORSES; KERATAN SULFATE; MALE; PHYSICAL CONDITIONING, ANIMAL;

EID: 0036561130     PISSN: 0931184X     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1439-0442.2002.00434.x     Document Type: Article

References (14)

1. Alwan, W. H., S. D. Carter, D. Bennett, S. A. May, and G. B. Edwards, 1990. Cartilage breakdown in equine osteoarthritis measurement of keratan sulphate by an ELISA system. Res. Vet. Sci. 49, 56-60.
2. Buschmann, M. D., Y. A. Gluzband, A. J. Grodzinsky, and E. B. Hunziker, 1995: Mechanical compression modulates matrix biosynthesis in chondrocyte/agarose culture. J. Cell Sci. 108, 1497-1508.
3. van den Hoogen, B. M., C. H. van de Lest, P. R. van Weeren, L. M. van Golde, and A. Barneveld, 1999. Effect of exercise on the proteoglycan metabolism of articular cartilage in growing foals. Equine Vet. J. Suppl. 31, 62-66.
4. Lee, D. A , T. Noguchi, S. P. Frean, P. Lees, and D. L. Bader, 2000: The influence of mechanical loading on isolated chondrocytes seeded in agarose constructs. Biorheology 37, 149-161.
5. Leipold, H. R., R. L Goldberg, and G. Lust, 1989. Canine serum keratan sulfate and hyaluronate concentrations. Relationship to age and osteoarthritis. Arthritis Rheum. 32, 312-321.
6. van de Lest, C. H., B. M. van den Hoogen, and P. R. van Weeren, 2000: Loading induced changes in synovial fluid affect cartilage metabolism. Biorheology 37, 45-55.
7. Okumura, M., and T. Fujinaga, 1998: Establishment of a monoclonal antibody (1/14/16H9) for detection of equine keratan sulfate. Am. J. Vet. Res. 59, 1203-1208.
8. Okumura, M., T. Fujinaga, E. Urakawa, M. Tagami. and K. Tsukiyama, 1997: Evaluation of the catabolic activity of cartilage by measurement of serum keratan sulfate concentration in foals. Am J Vet Res. 58, 925-929.
9. Okumura, M., M. Tagami, and T. Fujinaga, 1998: Measurement of serum and synovial fluid keratan sulphate and antibody to collagen type II in equine osteoarthntis J. Vet. Med. A 45, 513-516.
10. Okumura, M., M. Tagami, and T. Fujinaga, 2000: Consideration of the role of antigenic keratan sulphate reacting to a 1/14/16H9 antibody as a molecular marker to monitor cartilage metabolism in horses. J. Vet. Med. Sci. 62, 281-285.
11. Roos, H., L. Dahlberg, L. A. Hoerrner, M. W. Lark, E. J. Thonar, M. Shinmei, U. Lindqvist, and L. S. Lohmander, 1995: Markers of cartilage matrix metabolism in human joint fluid and serum: the effect of exercise. Osteoarthritis Cartilage 3, 7-14.
12. Saamanen, A. M., M. Tammi, J. Jurvelin, I. Kiviranta, and H. J. Helminen, 1990: Proteoglycan alterations following immobilization and remobilization in the articular cartilage of young canine knee (stifle) joint. J. Orthop. Res 8, 863-873.
13. Saamanen, A. M , M. Tammi, I. Kiviranta, J. Jurvelin, and H. J. Helminen. 1987: Maturation of proteoglycan matrix in articular cartilage under increased and decreased joint loading. A study in young rabbits. Connect. Tissue Res. 16, 163-175.
14. Todhunter, R. J., A. E Yeager, K. P. Freeman, E J. Parente, and G. Lust, 1993: Keratan sulfate as a marker of articular cartilage catabolism and joint treatment in ponies. Am. J. Vet. Res. 54, 1007-1016.