Effect of β1-selective adrenergic blockade on maximal blood lactate steady state in healthy men

European Journal of Applied Physiology

Volumn 87, Issue 1, 2002, Pages 66-71

  Wonisch, Manfred ^b   Hofmann, Peter ^b   Fruhwald, Friedrich M ^b   Hoedl, Ronald ^b   Schwaberger, Günther ^b   Pokan, Rochus ^b   Von Duvillard, Serge P ^a   Klein, Werner ^c  

^a UNIVERSITY OF NORTH DAKOTA   (United States)

^b UNIVERSITY OF GRAZ   (Austria)

^c UNIVERSITY OF VIENNA   (Austria)

Author keywords

Bisoprolol; Lactate turning point; Maximal lactate steady state; Oxygen pulse; Ratings of perceived exertion

Indexed keywords

BETA 1 ADRENERGIC RECEPTOR BLOCKING AGENT; BISOPROLOL; CARBON DIOXIDE; PLACEBO; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; LACTIC ACID;

ADRENERGIC RECEPTOR BLOCKING; ADULT; ANAEROBIC METABOLISM; ARTICLE; BICYCLE ERGOMETER; BODY HEIGHT; BODY MASS; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CROSSOVER PROCEDURE; DOUBLE BLIND PROCEDURE; DRUG EFFECT; EXHAUSTION; HEART RATE; HUMAN; LACTATE BLOOD LEVEL; LUNG GAS EXCHANGE; LUNG MINUTE VOLUME; MALE; OXYGEN CONSUMPTION; PHASE TRANSITION; PRIORITY JOURNAL; REST; STEADY STATE; ANAEROBIC THRESHOLD; BLOOD; EXERCISE; RANDOMIZED CONTROLLED TRIAL;

ADRENERGIC BETA-ANTAGONISTS; ADULT; ANAEROBIC THRESHOLD; BISOPROLOL; CROSS-OVER STUDIES; DOUBLE-BLIND METHOD; EXERTION; HUMANS; LACTIC ACID; MALE;

EID: 0036559926     PISSN: 14396319     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00421-002-0595-3     Document Type: Article

References (30)

1. American College of Sports Medicine (2000) Guidelines for exercise testing and prescription. Lippincott Williams and Wilkins, Philadelphia, Pa., 165-199
2. Aunola S, Rusko H (1992) Does anaerobic threshold correlate with maximal lactate steady-state? J Sports Sci 10:309-323
3. Beneke R, Duvillard SP von (1996) Determination of maximal lactate steady state response in selected sports events. Med Sci Sports Exerc 28:241-245
4. Borg GA (1982) Psychological bases of perceived exertion. Med Sci Sports Exerc 14:377-381
5. Brion R, Carre F, Verdier J-C, Poncelet P, Douard H, Page E, Amoretti R, Gauthier J, Ducardonnet A, Gessin V, Dubanchet A (2000) Comparative effects of bisoprolol and nitrendipine on exercise capacity in hypertensive patients with regular physical activity. J Cardiovasc Pharmacol 35:78-83
6. Brooks GA, Fahey TD, White TP, Baldwin KM (2000) Exercise physiology: human bioenergetics and its applications, 3rd edn. Mayfield Publishing Company, Mountain View, Calif., 317-338, 458-475
7. Davis A, Bassett J, Hughes P, Gass GC (1983) Anaerobic threshold and lactate turnpoint. Eur J Appl Physiol 50:383-392
8. 2-uptake and carbohydrate metabolism. Z Kardiol 68:503-509
9. Frisk-Homberg M, Juhlin-Dannfelt A, Astrom H (1985) Haemodynamic and metabolic responses to prolonged exercise after chronic β1-adrenoceptor blockade in hypertensive man. Clin Physiol 5:231-242
10. Fritzsche RG, Switzer TW, Bradley JH, Coyle EF (1999) Stroke volume decline during prolonged exercise is influenced by the increase in heart rate. J Appl Physiol 86:799-805
11. Gullestad L, Dolva LO, Nordby G, Skaaraas K, Larsen S, Kjekshus J (1989) The importance of potassium and lactate for maximal exercise performance during beta blockade. Scand J Clin Invest 49:521-528
12. Hambrecht RP, Niebauer J, Fiehn E, Marburger CT, Muth T, Offner B, Kuebler W, Schuler GC (1995) Effect of acute β-adrenergic blockade on the relationship between ventilatory and plasma lactate threshold. Int J Sports Med 16:219-224
13. Hofmann P, Bunc V, Leitner H, Pokan R, Gaisl G (1994a) Heart rate threshold related to lactate turn point and steady state exercise on cycle ergometer. Eur J Appl Physiol 69:132-139
14. Hofmann P, Pokan R, Preidler K, Leitner H, Szolar D, Eber B, Schwaberger G (1994b) Relationship between heart rate threshold, lactate turn point and myocardial function. Int J Sports Med 15:232-237
15. 2 to steady state of submaximal exercise with β-blockade. Eur J Appl Physiol 52:107-110
16. Kendall MJ (1981) Are selective beta-adrenoceptor blocking drugs an advantage? J R Coll Physicians Lond 15:33-40
17. 1/2-blockade. Z Kardiol 73:380-387
18. 1-blockade. Eur J Appl Physiol 56:292-298
19. Levy WC, Cerqueira MD, Abrass IB, Schwartz RS, Stratton JR (1993) Endurance exercise training augments diastolic filling at rest and during exercise in healthy young and older men. Circulation 88:116-126
20. Mader H, Heck H (1986) A theory of the metabolic origin of "anaerobic threshold". Int J Sports Med 7:45-65
21. Mandinov L, Eberli FR, Seiler C, Hess OM (2000) Diastolic heart failure. Cardiovasc Res 45:813-825
22. 1-selective and nonselective beta-adrenoceptor blockade during exercise conditioning in healthy adults. Am J Cardiol 53:1565-1661
23. Pokan R, Hofmann P, Duvillard SP von, Beaufort F, Smekal G, Gasser R, Klein W, Bachl N, Schmid P (1998) The heart rate performance curve and left ventricular function during exercise in patients after myocardial infarction. Med Sci Sports Exerc 30:1475-1480
24. Reybrouck T, Amery A, Billiet L (1977) Haemodynamic response to graded exercise after chronic beta-adrenergic blockade. J Appl Physiol 42:133-138
25. Schnabel A, Kindermann W, Salas-Fraire O, Cassens J, Steinkraus V (1983) Effect of β-adrenergic blockade on supramaximal exercise capacity. Int J Sports Med 4:278-281
26. Sklar J, Johnston GD, Overlie P, Gerber JG, Brammell HL, Gal J, Nies AS (1982) The effects of a cardioselective (metoprolol) and a nonselective (propranolol) beta-adrenergic blocker on the response to dynamic exercise in normal men. Circulation 65:894-899
27. Vanhees L, Defoor JGM, Schepers D, Lijnen P, Peeters BYM, Lacante PHL, Fagard RH (2000) Effect of bisoprolol and atenolol on endurance exercise capacity in healthy men. J Hypertens 18:35-43
28. Wasserman K (1988) New concepts in assessing cardiovascular function. Circulation 78:1060-1071
29. Wittke R, Kemmler W (1999) Effects of metoprolol (M CR/Zok) on the physical endurance performance of patients with arterial hypertension. Clin Drug Invest 17:255-263
30. Yoshida T (1984) Effect of dietary modifications on lactate threshold and onset of blood lactate accumulation during incremental exercise. Eur J Appl Physiol 53:200-205