Increased responsiveness of hypoxic endothelial cells to FGF2 is mediated by HIF-1α-dependent regulation of enzymes involved in synthesis of heparan sulfate FGF2-binding sites

Journal of Cell Science

Volumn 115, Issue 9, 2002, Pages 1951-1959

  Li, Jian ^a   Shworak, Nicholas W ^a   Simons, Michael ^a  

^a DARTMOUTH HITCHCOCK MEDICAL CENTER   (United States)

Author keywords

Angiogenesis; Endothelial cells; FGF2; Heparan sulfate; Hypoxia; Signaling

Indexed keywords

CHONDROITIN SULFATE; FIBROBLAST GROWTH FACTOR 2; HEPARAN SULFATE; HYPOXIA INDUCIBLE FACTOR 1ALPHA; SULFOTRANSFERASE; TRANSFERASE; FIBROBLAST GROWTH FACTOR RECEPTOR; GLYCOSAMINOGLYCAN; HIF1A PROTEIN, HUMAN; TRANSCRIPTION FACTOR;

ADENOVIRUS; ANIMAL CELL; ARTICLE; BINDING SITE; CELL CULTURE; CELL GROWTH; CELL HYPOXIA; CELL STIMULATION; CELL SURFACE; CONTROLLED STUDY; ENDOTHELIUM CELL; ENZYME REGULATION; GENE EXPRESSION; GENETIC TRANSDUCTION; HEART BLOOD VESSEL; HUMAN; HUMAN CELL; NEWBORN; NONHUMAN; PRIORITY JOURNAL; RAT; SULFATION; UMBILICAL VEIN; ANGIOGENESIS; ANIMAL; ANOXIA; BIOSYNTHESIS; CELL DIVISION; DRUG EFFECT; ENZYMOLOGY; GENE EXPRESSION REGULATION; GROWTH, DEVELOPMENT AND AGING; METABOLISM; PHYSIOLOGY; PROTEIN BINDING; SIGNAL TRANSDUCTION; VASCULAR ENDOTHELIUM;

ANIMAL; ANIMALS, NEWBORN; ANOXIA; BINDING SITES; CELL DIVISION; CELLS, CULTURED; CHONDROITIN SULFATES; ENDOTHELIUM, VASCULAR; FIBROBLAST GROWTH FACTOR 2; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GLYCOSAMINOGLYCANS; HEPARITIN SULFATE; HUMAN; NEOVASCULARIZATION, PHYSIOLOGIC; PROTEIN BINDING; RATS; RECEPTORS, FIBROBLAST GROWTH FACTOR; SIGNAL TRANSDUCTION; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, P.H.S.; TRANSCRIPTION FACTORS; ANIMALS; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT;

EID: 0036558290     PISSN: 00219533     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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