Quaternary structure and function of transport proteins

Trends in Biochemical Sciences

Volumn 27, Issue 5, 2002, Pages 242-249

  Veenhoff, Liesbeth M ^a   Heuberger, Esther H M L ^a   Poolman, Bert ^a  

^a UNIVERSITY OF GRONINGEN   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

ABC TRANSPORTER; ANTIPORTER; CARRIER PROTEIN; DICARBOXYLIC AMINO ACID; GALACTOSIDE; ORGANOPHOSPHATE; DETERGENT;

ALPHA HELIX; ANION EXCHANGE; CATALYSIS; CELL COMMUNICATION; CELL MEMBRANE; HUMAN; MEMBRANE STABILIZATION; NONHUMAN; OLIGOMERIZATION; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN FAMILY; PROTEIN FUNCTION; PROTEIN QUATERNARY STRUCTURE; PROTEIN SECONDARY STRUCTURE; REGULATORY MECHANISM; REVIEW; SIGNAL TRANSDUCTION; SOLUTE; SPECIES DIFFERENCE; ANIMAL; CHEMICAL STRUCTURE; CHEMISTRY; METABOLISM; PHYSIOLOGY; SOLUTION AND SOLUBILITY; TRANSPORT AT THE CELLULAR LEVEL;

ANIMAL; BIOLOGICAL TRANSPORT; CELL MEMBRANE; DETERGENTS; HUMAN; MEMBRANE TRANSPORT PROTEINS; MODELS, MOLECULAR; PROTEIN STRUCTURE, QUATERNARY; PROTEIN STRUCTURE, SECONDARY; SOLUTIONS; SUPPORT, NON-U.S. GOV'T; ANIMALS; HUMANS;

EID: 0036558026     PISSN: 09680004     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0968-0004(02)02077-7     Document Type: Review

References (49)

1. Analysis of integral membrane protein contributions to the deformability and stability of the human erythrocyte membrane
2. Interaction between proteins localized in membranes
3. The kamikaze approach to membrane transport
4. The lactose transport protein is a cooperative dimer with two sugar translocation pathways
5. Glucose transporter function is controlled by transporter oligomeric structure. A single, intramolecular disulfide promotes GLUT1 tetramerization
6. Oligomeric state of membrane transport analyzed with blue native electrophoresis and analytical ultracentrifugation
7. Quaternary structure of the lactose transport protein of Streptococcus thermophilus in the detergent-solubilized and membrane-reconstituted state
8. Characterization of membrane proteins in detergent solutions
9. A mechanism to alter reversibly the oligomeric state of a membrane-bound protein demonstrated with Escherichia coli EII and in solution
10. Structural analysis of cloned plasma membrane proteins by freeze-fracture electron microscopy
11. Pentameric assembly of a neuronal glutamate transporter
12. Molecular characterization of Vibrio parahaemolyticus vSGLT: A model for sodium-coupled sugar cotransporters
13. The structure of glutamate transporters shows channel-like features
14. The size of the lactose permease derived from rotational diffusion measurements
15. Rotational mobility and orientational stability of a transport protein in lipid membranes
16. Reconstitution of membrane proteins into giant unilamellar vesicles via peptide-induced fusion
17. Ultrahigh-resolution multicolor colocalization of single fluorescent probes
18. Properties of permease dimer, a fusion protein containing two lactose permease molecules from Escherichia coli
19. The phosphate carrier from yeast mitochondria. Dimerization is a prerequisite for function
20. UhpT, the sugar phosphate antiporter of Escherichia coli, functions as a monomer
21. Three-dimensional structure of the ion-coupled transport protein NhaA
22. Projection structure and molecular architecture of OxlT, a bacterial membrane transporter
23. The quaternary molecular architecture of TetA, a secondary tetracycline transporter from Escherichia coli
24. The NH2-terminal half of the Tn10-specified tetracycline efflux protein TetA contains a dimerization domain
25. Evidence that TET protein functions as a multimer in the inner membrane of Escherichia coli
26. + antiporter of Escherichia coli in the membrane and its functional and structural consequences
27. Three-dimensional map of the dimeric membrane domain of the human erythrocyte anion exchanger, Band 3
28. Kinetics of conformational changes associated with inhibitor binding to the purified band 3 transporter. Direct observation of allosteric subunit interactions
29. Analysis of the oligomeric state of Band 3, the anion transport protein of the human erythrocyte membrane, by size exclusion high performance liquid chromatography. Oligomeric stability and origin of heterogeneity
30. Band 3 protein: Structure, flexibility and function
31. The projection structure of EmrE, a proton-linked multidrug transporter from Escherichia coli, at 7 Å resolution
32. In vitro monomer swapping in EmrE, a multidrug transporter from Escherichia coli, reveals that the oligomer is the functional unit
33. Dominant negative isoform of rat norepinephrine transporter produced by alternative RNA splicing
34. Identification of alternative splicing forms of GLT-1 mRNA in the spinal cord of amyotrophic lateral sclerosis patients
35. ATP-dependent substrate occlusion by the human erythrocyte sugar transporter
36. Morphology of proteoliposomes reconstituted with purified lac carrier protein from Escherichia coli
37. Mutations in the lacY gene of Escherichia coli define functional organization of lactose permease
38. Two-dimensional crystallization of Escherichia coli lactose permease
39. The Leishmania GDP-mannose transporter is an autonomous, multi-specific, hexameric complex of LPG2 subunits
40. Distinct protein domains of the yeast golgi GDP-mannose transporter mediate oligomer assembly and export from the endoplasmic reticulum
41. Oligomerization of the human serotonin transporter and of the rat GABA transporter 1 visualized by fluorescence resonance energy transfer microscopy in living cells
42. Hydrodynamic properties and immunological identification of the sodium- and chloride-coupled glycine transporter
43. Brain glutamate transporter proteins form homomultimers
44. (+)-dependent citrate carrier of Klebsiella pneumoniae
45. The formation of a disulfide cross-link between the two subunits demonstrates the dimeric structure of the mitochondrial oxoglutarate carrier
46. - cotransporter (NKCC1) is a homodimer
47. Projection structure of NhaA, a secondary transporter from Escherichia coli, at 4.0 Å resolution
48. + exchanger isoforms NHE1 and NHE3 exist as stable dimers in membranes with a high degree of specificity for homodimers
49. +/Pi cotransporter is a monomer