Propylene glycol monomethyl ether occupational exposure. 3. Exposure of human volunteers

International Archives of Occupational and Environmental Health

Volumn 75, Issue 4, 2002, Pages 203-208

  Devanthéry, Anne ^a   Berode, Michèle ^a   Droz, Pierre Olivier ^a  

^a UNIVERSITY OF LAUSANNE   (Switzerland)

Author keywords

Biological monitoringd; Human exposure; PGME; Toxicokinetics; Urine

Indexed keywords

CHLORIDE; IMIDAZOLE; INDUSTRIAL CHEMICAL; PROPANEDIOL DERIVATIVE; PROPYLENE GLYCOL METHYL ETHER; UNCLASSIFIED DRUG;

ADULT; ARTICLE; BIOLOGICAL MONITORING; BLOOD ANALYSIS; CONTROLLED STUDY; DERIVATIZATION; EXPIRED AIR; GAS CHROMATOGRAPHY; HUMAN; HYDROLYSIS; INDUSTRY; ISOMER; LIQUID CHROMATOGRAPHY; MALE; METABOLISM; NORMAL HUMAN; OCCUPATIONAL EXPOSURE; OUTCOMES RESEARCH; PROTECTIVE EQUIPMENT; RESPIRATORY SYSTEM; RESPIRATORY TRACT PARAMETERS; SKIN ABSORPTION; SOLID PHASE EXTRACTION; TOXICOKINETICS; TOXICOLOGICAL PARAMETERS; URINARY EXCRETION; URINE LEVEL; VOLUNTEER;

ADULT; BREATH TESTS; CHROMATOGRAPHY, GAS; HALF-LIFE; HUMANS; INHALATION EXPOSURE; MALE; OCCUPATIONAL EXPOSURE; PROPYLENE GLYCOLS; RESPIRATORY PROTECTIVE DEVICES;

EID: 0036556260     PISSN: 03400131     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00420-001-0310-4     Document Type: Article

References (13)

1. American Conference of Governmental Industrial Hygienists (ACGIH) (1999) Threshold Limit Values for Chemical Substances and Physical Agents, Biological Exposure Indices. ACGIH, Cincinnati
2. Dentan A, Devanthéry A, De Peyer JE, et al. (2000) Propylene glycol monomethyl ether (PGME) occupational exposure 2. Identification of products containing of PGME, their importance and their use in Switzerland. Int Arch Occup Environ Health 73:349-351
3. Devanthéry A, Dentan A, Berode M, et al (2000) Propylene glycol monomethyl ether (PGME) occupational exposure 1. Biomonitoring by analysis of PGME in urine. Int Arch Occup Environ Health 73: 311-315
4. Droz PO, Guillemin MP (1983) Human styrene exposure v. development of a model for biological monitoring. Int Arch Occup Environ Health 53:19-36
5. European Centre for Ecotoxicology and Toxicology of Chemicals (ECETOC) (1995) The Toxicology of Glycol Ethers and its Relevance to Man (technical report no. 64). ECETOC, Brussels
6. Jones K, Dyne D, Cocker J, et al. (1997) A biological monitoring study of 1-methoxy-2-propanol: Analytical method development and a human volunteer study. Sci Total Environ 199:23-30
7. Miller R (1987) Metabolism and disposition of glycol ethers. Drug Metab Rev 18:1-22
8. Miller R, Hermann EA, Langvardt PW, et al. (1983) Comparative metabolism and disposition of ethylene glycol monomethyl ether in male rats. Toxicol Appl Pharmacol 67:229-237
9. Miller R, Hermann EA, Young JT, et al. (1984) Ethylene glycol monomethyl ether and propylene glycol monomethyl ether: Metabolism, disposition and subchronic inhalation toxicity studies. Environ Health Perspect 57:233-239
10. Miller R, Langvardt PW, Calhoun LL, et al. (1986) Metabolism and disposition of PGME beta isomer in male rats. Toxicol Appl Pharmacol 83:170-177
11. National Institute for Occupational Safety and Health (NIOSH) (1995) Alcohol analysis no. 1403. In: NIOSH Manual of Analytical Methods, 4th edn. NIOSH, Cincinnati
12. Söhnlein B, Goën T, Drexler H, et al. (1994) Metabolism and kinetics of elimination of 1-methoxy-2-propanol and 1-ethoxy-2-propanol in man. Poster presentation at the International Symposium on Health Hazards of Glycol Ethers, Nancy-Pont à Mousson
13. Stewart RD, Baretta ED, Dodd HC, et al. (1970) Experimental human exposure to vapor of propylene glycol monomethyl ether. Arch Environ Health 20:218-223