Additional lunchtime basal insulin during insulin lispro intensive therapy in a randomized, multicenter, crossover study in adults: A real-life design

Diabetes Care

Volumn 25, Issue 4, 2002, Pages 712-717

  Stades, Aline M E ^a   Hoekstra, Joost B L ^b   Van Den Tweel, Ingeborg ^c   Erkelens, D Willem ^d   Holleman, Frits ^b  

^a DEPARTMENT OF SURGERY   (Netherlands)

^b ACADEMIC MEDICAL CENTER   (Netherlands)

^c UTRECHT UNIVERSITY   (Netherlands)

^d UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

HEMOGLOBIN A1C; INSULIN; INSULIN LISPRO; ANTIDIABETIC AGENT; DRUG DERIVATIVE; GLYCOSYLATED HEMOGLOBIN; ISOPHANE INSULIN;

ADULT; ARTICLE; CLINICAL TRIAL; COMPARATIVE STUDY; CONFIDENCE INTERVAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CROSSOVER PROCEDURE; GLUCOSE BLOOD LEVEL; HUMAN; HYPOGLYCEMIA; INSULIN DEPENDENT DIABETES MELLITUS; MULTICENTER STUDY; PROTEIN BLOOD LEVEL; RANDOMIZED CONTROLLED TRIAL; STATISTICAL ANALYSIS; STUDENT T TEST; BLOOD; BODY MASS; DRUG ADMINISTRATION; EATING; FEMALE; MALE; METABOLISM;

ADULT; BLOOD GLUCOSE; BODY MASS INDEX; CROSS-OVER STUDIES; DIABETES MELLITUS, TYPE 1; DRUG ADMINISTRATION SCHEDULE; EATING; FEMALE; HEMOGLOBIN A, GLYCOSYLATED; HUMANS; HYPOGLYCEMIA; HYPOGLYCEMIC AGENTS; INSULIN; INSULIN, ISOPHANE; MALE;

EID: 0036548048     PISSN: 01495992     EISSN: None     Source Type: Journal    
DOI: 10.2337/diacare.25.4.712     Document Type: Article

References (13)

1. Holleman F, Schmitt H, Rottiers R, Rees A, Symanowski S, Anderson JH: Reduced frequency of severe hypoglycemia and coma in well-controlled IDDM patients treated with insulin lispro: the Benelux-UK Insulin Lispro Study Group. Diabetes Care 20:1827-1832, 1997
2. Heller SR, Amiel SA, Mansell P: Effect of the fast-acting insulin analog lispro on the risk of nocturnal hypoglycemia during intensified insulin therapy: U.K. Lispro Study Group. Diabetes Care 22:1607-1611, 1999
3. Anderson JH Jr, Brunelle RL, Koivisto VA, Pfützner A, Trautmann ME, Vignati L, DiMarchi R: Reduction of postprandial hyperglycemia and frequency of hypoglycemia in IDDM patients on insulin-analog treatment. Diabetes 46:265-270, 1997
4. Holleman F, Hoekstra JB: Insulin lispro. N Engl J Med 337:176-183, 1997
5. Lalli C, Ciofetta M, Del Sindaco P, Torlone E, Pampanelli S, Compagnucci P, Cartechini MG, Bartocci L, Brunetti P, Bolli GB: Long-term intensive treatment of type 1 diabetes with the short-acting insulin analog lispro in variable combination with NPH insulin at mealtime. Diabetes Care 22:468-477, 1999
6. Ebeling P, Jansson PA, Smith U, Lalli C, Bolli GB, Koivisto VA: Strategies toward improved control during insulin lispro therapy in IDDM. Diabetes Care 20:1287-1289, 1997
7. Karsidag K, Satman I, Dinccag N, Altuntas Y, Karadeniz S, Yilmaz MT: Comparison of metabolic control in IDDM with two different intensive regimens of [Lys(B28), Pro(B29)]-human insulin (lispro) plus NPH-insulin. Diabetologia 39 (Suppl. 1): A222, 1996
8. Del Sindaco P, Ciofetta M, Lalli C, Perriello G, Pampanelli S, Torlone E, Brunetti P, Bolli GB: Use of the short-acting insulin analogue lispro in intensive treatment of type 1 diabetes mellitus: importance of appropriate replacement of basal insulin and time-interval injection-meal. Diabet Med 15:592-600, 1998
9. Gerlo E, Gorus F: Calibration of ion-exchange HPLC measurements of glycohemoglobin: effect on interassay precision. Clin Chem 43:2353-2357, 1997
10. Pocock SJ: Crossover Trials. Chichester, U.K.: John Wiley & Sons, 1983
11. Torlone E, Pampanelli S, Lalli C, Del Sindaco P, Di Vincenzo A, Rambotti AM, Rambotti AM, Modarelli F, Epifano L, Kassi G, Perriello G, Brunetti P, Bolli G: Effects of the short-acting insulin analog [Lys(B28),Pro(B29)] on postprandial blood glucose control in IDDM. Diabetes Care 19:945-952, 1996
12. Zinman B, Ross S, Campos RV, Strack T: Effectiveness of human ultralente versus NPH insulin in providing basal insulin replacement for an insulin lispro multiple daily injection regimen: a double-blind randomized prospective trial. Diabetes Care 22:603-608, 1999
13. de VriesJH, Lindholm A, Heine RJ, Home PD: A randomized trial of insulin aspart with intensified basal NPH insulin supplementation in type 1 diabetics. Diabetologia 44 (Suppl. 1):A209, 2001