Age dimorphism in the association between growth-hormone status and the respiratory quotient

Obesity Research

Volumn 10, Issue 4, 2002, Pages 284-290

  Christiansen, Jens J ^a   Vahl, Nina ^a   Fisker, Sanne ^a   Møller, Niels ^a   Christiansen, Jens S ^a   Jørgensen, Jens O L ^a  

^a AARHUS UNIVERSITY HOSPITAL   (Denmark)

Author keywords

Body composition; Cross sectional study; Deconvolution analysis; Lipolysis

Indexed keywords

CARBON DIOXIDE; DIAGNOSTIC AGENT; FATTY ACID; HUMAN GROWTH HORMONE; SOMATOMEDIN C; TRIACYLGLYCEROL;

ADULT; AGING; ARTICLE; BLOOD; BODY COMPOSITION; BODY MASS; COMPARATIVE STUDY; CROSS-SECTIONAL STUDY; ENERGY METABOLISM; FEMALE; FITNESS; HUMAN; LIPOLYSIS; MALE; MIDDLE AGED; OXYGEN CONSUMPTION; REGRESSION ANALYSIS; REST;

ADULT; AGING; BODY COMPOSITION; BODY MASS INDEX; CARBON DIOXIDE; CROSS-SECTIONAL STUDIES; ENERGY METABOLISM; FATTY ACIDS, NONESTERIFIED; FEMALE; HUMAN GROWTH HORMONE; HUMANS; INSULIN-LIKE GROWTH FACTOR I; LIPOLYSIS; MALE; MIDDLE AGED; OXYGEN CONSUMPTION; PHYSICAL FITNESS; REGRESSION ANALYSIS; REST; TRIGLYCERIDES;

EID: 0036548010     PISSN: 10717323     EISSN: None     Source Type: Journal    
DOI: 10.1038/oby.2002.39     Document Type: Article

References (28)

1. McGinnis JM, Foege WH. Actual causes of death in the United States. JAMA. 1993;10-11 ;270:2207-12.
2. McGinnis JM, Foege WH. Actual causes of death in the United States. JAMA. 1993;10-11 ;270:2207-12.
3. Zurlo F, Lillioja S, Esposito-Del Puente A, et al. Low ratio of fat to carbohydrate oxidation as predictor of weight gain: study of 24-h RQ. Am J Physio Endocrinol Metab. 1990;259: E650-E67.
4. Seidell JC, Muller DC, Sorkin JD, Andres R. Fasting respiratory exchange ratio and resting metabolic rate as predictors of weight gain: the Baltimore longitudinal study on aging. Int J Obes Relat Metab Disord. 1992;16:667-74.
5. McNeill G, Bruce AC, Ralph A, James WP. Inter-individual differences in fasting nutrient oxidation and the influence of diet composition. Int J Obes. 1988;12:455-63.
6. Toubro S, Sorensen TI, Hindsberger C, Christensen NJ, Astrup A. Twenty-four-hour respiratory quotient. The role of diet and familial resemblance. J Clin Endoc Metab. 1998;8: 2758-64.
7. Weyer C, Snitker S, Rising R, Bogardus C, Ravussin E. Determinants of energy expenditure and fuel utilization in man: effects of body composition, age, sex, ethnicity, and glucose tolerance in 916 subjects. Int J Obes Relat Metab Disord. 1999;23:715-22.
8. Astrup A, Buemann B, Christensen NJ, et al. The contribution of body composition, substrates, and hormones to the variability in energy expenditure and substrate utilization in premenopausal women. J Clin Endocr Metab. 1992;74:279-86.
9. Snitker S, Tataranni PA, Ravussin E. Respiratory quotient is inversely associated with muscle sympathetic nerve activity. J Clin Endocr Metab. 1998;83:3977-9.
10. Press M. Growth hormone and metabolism. Diabetes Metab Rev. 1988;4:391-414.
11. Davidson MB. Effect of growth hormone on carbohydrate and lipid metabolism. Endo Rev. 1987;8:115-31.
12. Moller N, Jorgensen JO, Schmitz O, et al. Effects of a growth hormone pulse on total and forearm substrate fluxes in humans. Am J Physiol Endocrinol Metab. 1990;258:E86-E91.
13. Moller N, Schmitz O, Joorgensen JO, et al. Basal-and insulin-stimulated substrate metabolism in patients with active acromegaly before and after adenomectomy. J Clin Endocr Metab. 1992;74:1012-9.
14. Vahl N, Jorgensen JO, Skjaerbaek C, Veldhuis JD, Orskov H, Christiansen JS. Abdominal adiposity rather than age and sex predicts mass and regularity of GH secretion in healthy adults. Am J Physiol Endocrinol Metab. 1997;272: E1108-E1116.
15. Vahl N, Jorgensen JO, Jurik AG, Christiansen JS. Abdominal adiposity and physical fitness are major determinants of the age-associated decline in stimulated GH secretion in healthy adults. J Clin Endocr Metab. 1996;81:2209-15.
16. Vahl N, Moller N, Lauritzen T, Christiansen JS, Jorgensen JO. Metabolic effects and pharmacokinetics of a growth hormone pulse in healthy adults: relation to age, sex, and body composition. J Clin Endocr Metab. 1997;82:3612-8.
17. Veldhuis JD, Carlson ML, Johnson ML. The pituitary gland secretes in bursts: appraising the nature of glandular secretory impulses by simultaneous multiple-parameter deconvolution of plasma hormone concentrations. Proc Natl Acad Sci USA. 1987;84:7686-90.
18. Frystyk J, Dinesen B, Orskov H. Non-competitive time-resolved immunofluorometric assays for determination of human insulin-like growth factor I and II. Growth Regul 1995; 5:169-76.
19. Moller N, Jorgensen JO, Alberti KG, Flyvbjerg A, Schmitz O. Short-term effects of growth hormone on fuel oxidation and regional substrate metabolism in normal man. J Clin Endocr Metab. 1990;70:1179-86.
20. Moller J, Jorgensen JO, Moller N, Christiansen JS, Week J. Effects of growth hormone administration on fuel oxidation and thyroid function in normal man. Metab. 1992;41:728-31.
21. Jorgensen JO, Pedersen SB, Borglum J, et al. Fuel metabolism, energy expenditure, and thyroid function in growth hormone-treated obese women. A double-blind placebo-controlled study. Metabolism. 1994;43:872-7.
22. Jorgensen JO, Moller J, Alberti KG, et al. Marked effects of sustained low growth hormone (GH) levels on day-to-day fuel metabolism: studies in GH-deficient patients and healthy untreated subjects. J Clin Endocr Metab. 1993;77:1589-96.
23. Moller N, Schmitz O, Porksen N, Moller J, Jorgensen JO. Dose-response studies on the metabolic effects of a growth hormone pulse in humans. Metabolism. 1992;41:172-5.
24. Quabbe HJ, Bratzke HJ, Siegers U, Elban K. Studies on the relationship between plasma free fatty acids and growth hormone secretion in man. J Clin Invest. 1972;51:2388-98.
25. Kojima M, Hosoda H, Date Y, Nakazato M, Matsuo H, Kangawa K. Ghrelin is a growth-hormone-releasing acylated peptide from stomach. Nature. 1999;402:656-60.
26. Leung Kin Chuen, Ho, Ken K. Y. Stimulation of mitochondrial fatty acid oxidation by growth hormone in human fibroblasts. J Clin Endocr Metab. 1997;82:4208-13.
27. Richelsen B, Pedersen SB, Borglum JD, Moller-Pedersen T, Jorgensen J, Jorgensen JO. Growth Hormone Treatment of Obese Women for 5 Wk: Effect on Body Composition and Adipose Tissue LPL Activity. Am J Physiol Endocrinol Metab. 1994;266:E211-E216.
28. Rudling M, Norstedt G, Olivecrona H, Reihner E, Gustafsson J, Angelin B. Importance of growth hormone for the induction of hepatic low density lipoprotein receptors. Proc Natl Acad Sci. 1992;89:6983-7.