A countermeasure to ameliorate immune dysfunction in in vitro simulated microgravity environment: Role of cellular nucleotide nutrition

In Vitro Cellular and Developmental Biology - Animal

Volumn 38, Issue 4, 2002, Pages 213-217

  Hales, N W ^a   Yamauchi, K ^a   Alicea, A ^a   Sundaresan, A ^b   Pellis, N R ^c   Kulkarni, A D ^a  

^a UNIVERSITY OF TEXAS MEDICAL SCHOOL   (United States)

^b WYLE LABORATORIES   (United States)

^c NASA JOHNSON SPACE CENTER   (United States)

Author keywords

Cell nutrition; In vitro cultures; Nucleotides; Simulated microgravity; T cells

Indexed keywords

CYTIDINE; CYTOKINE; GAMMA INTERFERON; GUANOSINE PHOSPHATE; INOSINE; INTERLEUKIN 1BETA; INTERLEUKIN 2; INTERLEUKIN 3; NUCLEOSIDE DERIVATIVE; NUCLEOTIDE DERIVATIVE; PHYTOHEMAGGLUTININ; PYRIMIDINE DERIVATIVE; THYMIDINE; TUMOR NECROSIS FACTOR ALPHA; URIDINE;

ANIMAL CELL; ARTICLE; BIOREACTOR; CELL CULTURE; CELL PROLIFERATION; CELL STIMULATION; CONTROLLED STUDY; COSMONAUT; CYTOKINE PRODUCTION; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; IMMUNE DEFICIENCY; IMMUNE RESPONSE; MALIGNANT NEOPLASTIC DISEASE; MICROGRAVITY; MITOGENESIS; MOUSE; NONHUMAN; NUTRITION; OPPORTUNISTIC INFECTION; SIMULATION; SPLEEN CELL; STRESS; SUPERNATANT; TRAVEL; WOUND HEALING;

NON-PROGRAMMATIC;

ANIMALS; BIOREACTORS; CELL CULTURE TECHNIQUES; FEMALE; LYMPHOCYTE ACTIVATION; LYMPHOCYTES; MICE; MICE, INBRED BALB C; REFERENCE VALUES; SPLEEN; WEIGHTLESSNESS SIMULATION;

ANIMALIA;

EID: 0036545626     PISSN: 10712690     EISSN: None     Source Type: Journal    
DOI: 10.1290/1071-2690(2002)038<0213:ACTAID>2.0.CO;2     Document Type: Article

References (21)

1. Nucleic acids and/or their components: A possible role in immune function
2. Dietary nucleosides and nucleotides improve cell-mediated immunity in mice
3. The effects of rM-CSF and rIL-6 therapy on immunosuppressed anti-orthostatically suspended mice
4. The effect of hypogravity and hypergravity on cells of the immune system
5. Response of cells to microgravity
6. The effect of hypogravity on human lymphocyte activation
7. Suppressed PHA activation of T lymphocytes in simulated microgravity is restored by direct activation of protein kinase C
8. Immune changes during long-duration missions
9. Effect of dietary nucleotides on response to bacterial infections
10. Modulation of delayed hypersensitivity in mice by dietary nucleotides
11. Immunohemopoietic effects of dietary nucleotide restriction in mice
12. The role of dietary source of nucleotides in immune function: A review
13. Nutrition countermeasure and immune function in microgravity
14. Immune changes in test animals during spaceflight
15. Effect of total parenteral nutrition with nulcleoside and nucleotide mixture on D-galactosamine induced liver injury in mice
16. Changes in gravity inhibit lymphocyte locomotion through type I collagen
17. Direct effect of microgravity (MG) on human lymphocytes: Functional and morphological aspects
18. Suppression of lymphocyte function in microgravity and potential impact on immunosurveillance
19. Cell culture for three-dimensional modeling in rotating-wall vessel: An application of simulated microgravity
20. Overview of spaceflight immunology
21. Simulated microgravity inhibits the genetic expression of interleukin-2 and its receptor in mitogens-activated T lymphocytes