Is residual confounding a reasonable explanation for the apparent protective effects of beta-carotene found in epidemiologic studies of lung cancer in smokers?

American Journal of Epidemiology

Volumn 155, Issue 7, 2002, Pages 622-628

  Stram, Daniel O ^a   Huberman, Mark ^a   Wu, Anna H ^a  

^a UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

Author keywords

Beta carotene; Lung neoplasms; Measurement error; Smoking

Indexed keywords

BETA CAROTENE;

CANCER;

ARTICLE; BLOOD LEVEL; CANCER RISK; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DIET SUPPLEMENTATION; EXPOSURE; HUMAN; LUNG CANCER; RANDOMIZED CONTROLLED TRIAL; SMOKING; STATISTICAL MODEL;

ANTIOXIDANTS; BETA CAROTENE; CONFOUNDING FACTORS (EPIDEMIOLOGY); EPIDEMIOLOGIC STUDIES; HUMANS; LUNG NEOPLASMS; MODELS, STATISTICAL; SMOKING;

EID: 0036532254     PISSN: 00029262     EISSN: None     Source Type: Journal    
DOI: 10.1093/aje/155.7.622     Document Type: Article

References (31)

1. Chemoprevention of lung cancer: The beta-Carotene and Retinol Efficacy Trial (CARET) in high-risk smokers and asbestos-exposed workers
2. Alpha-tocopherol and beta-carotene supplements and lung cancer incidence in the Alpha-Tocopherol, Beta-Carotene Cancer Prevention Study: Effects of base-line characteristics and study compliance
3. Lack of effect of long-term supplementation with beta carotene on the incidence of malignant neoplasms and cardiovascular disease
4. Serum levels of retinol, beta-carotene, and alpha-tocopherol in older adults
5. The relation of diet, cigarette smoking, and alcohol consumption to plasma beta-carotene and alpha-tocopherol levels
6. Determinants of plasma levels of beta-carotene and retinol
7. Dietary beta-carotene, cigarette smoking, and lung cancer in men
8. Food and nutrient intake differences between smokers and non-smokers in the US
9. Environmental carcinogens and anticarcinogens
10. Mismeasurement and the resonance of strong confounders: Uncorrelated measurement error
11. The effect of misclassification in the presence of covariates
12. Confounding and misclassification
13. Cigarette smoking and bronchial carcinoma: Dose and time relationships among regular smokers and life-long non-smokers
14. Cigarette consumption per adult of each sex in various countries
15. The validity of self-reported smoking: A review and meta-analysis
16. The contributions of cigarette yield, consumption, inhalation and puffing behaviour to the prediction of smoke exposure
17. Near-patient test for nicotine and its metabolites in saliva to assess smoking habit
18. Evaluation of nicotine, cotinine, thiocyanate, carboxyhemoglobin, and expired carbon monoxide as biochemical tobacco smoke uptake parameters
19. Self-reported smoking, cigarette yields and inhalation biochemistry related to the incidence of coronary heart disease: Results from the Scottish Heart Health Study
20. Exhaled carbon monoxide and urinary cotinine as measures of smoking in pregnancy
21. Validation of self-reported smoking by analysis of hair for nicotine and cotinine
22. Cotinine validation of self-reported smoking in commercially run community surveys
23. Cigarette yields of tar and nicotine and markers of exposure to tobacco smoke
24. Destruction of tocopherols, carotenoids, and retinol in human plasma by cigarette smoke
25. Beta-carotene and lung cancer: A case study
26. Prospective study of fruit and vegetable consumption and risk of lung cancer among men and women
27. Nicotine dependence and smoking topography among black and white women
28. Is serum cotinine a better measure of cigarette smoking than self-report?
29. Maternal smoking during pregnancy, urine cotinine concentrations, and birth outcomes. A prospective cohort study
30. Relationship between systemic markers of inflammation and serum beta-carotene levels
31. A multiethnic cohort in Hawaii and Los Angeles: Baseline characteristics