An HPLC method for the determination and pharmacokinetic study of cinnamic acid in the plasma of rats having taken the traditional Chinese medicinal preparation Ling-Gui-Zhu-Gan decoction

Journal of Chromatographic Science

Volumn 40, Issue 4, 2002, Pages 198-200

  Song, Zonghua ^a   Bi, Kaishun ^a   Luo, Xu ^a  

^a SHENYANG PHARMACEUTICAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ACETIC ACID; ACETIC ACID ETHYL ESTER; ACETONITRILE; BAIZHU; CARBON; CHINESE DRUG; CINNAMIC ACID; CINNAMOMUM CASSIA EXTRACT; FULING; GANCAO; GLYCYRRHIZA URALENSIS EXTRACT; GUIZHI; HYDROCHLORIC ACID; LING GUI ZHU GAN; METHANOL; PLANT EXTRACT; PORIA COCOS EXTRACT; UNCLASSIFIED DRUG;

ACIDIFICATION; ANIMAL EXPERIMENT; ARTICLE; CHINESE MEDICINE; CONTROLLED STUDY; DRUG BLOOD LEVEL; EXTRACTION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; NONHUMAN; RAT; ULTRAVIOLET RADIATION; VALIDATION PROCESS;

ANIMALIA; CASSIA; CINNAMOMUM; CINNAMOMUM CASSIA; COCOS; GLYCYRRHIZA; GLYCYRRHIZA URALENSIS; MOLVA MOLVA; PORIA COCOS;

EID: 0036526390     PISSN: 00219665     EISSN: None     Source Type: Journal    
DOI: 10.1093/chromsci/40.4.198     Document Type: Article

References (8)

1. The effect of "Ling Gui Shu Gan Tang" on cardiovascular system
2. Rapid analysis of Chinese medicines in quality evaluations. 1. Components of Cinnamoni cortex and Moutan cortex in "Hachimigan"
3. Determinations in Cinnamoni cortex by high-performance liquid chromatography
4. Quantitation of cinnamaldehyde and cinnamic acid in blood by HPLC
5. Metabolism of trans-cinnamic acid in the rat and the mouse and its variation with dose
6. Determination of cinnamic acid in human urine by differential-pulse polarography
7. Analytical methods validation: Bioavailability, bioequivalence, and pharmacokinetic studies
8. Validation of chromatographic methods in biomedical analysis viewpoint and discussion