Continuous-wave near-infrared spectroscopy using pathlength-independent hypoxia normalization

Journal of Biomedical Optics

Volumn 7, Issue 2, 2002, Pages 228-235

  Kennan, Richard P ^a   Behar, Kevin L ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Functional imaging; Hypoxia; Near infrared spectroscopy; Optical imaging

Indexed keywords

BLOOD; FLOW OF FLUIDS; HEMODYNAMICS; INFRARED SPECTROSCOPY; METABOLISM; OXYGEN; PHYSIOLOGY;

OPTICAL IMAGING;

MEDICAL IMAGING;

OXY;

CARBON DIOXIDE; OXYGEN;

ANIMAL; ARTICLE; BIOLOGICAL MODEL; BRAIN HYPOXIA; HYPEROXIA; IMAGE QUALITY; METABOLISM; METHODOLOGY; NEAR INFRARED SPECTROSCOPY; OPTICS; RAT; SPRAGUE DAWLEY RAT;

ANIMALS; CARBON DIOXIDE; HYPEROXIA; HYPOXIA, BRAIN; MODELS, BIOLOGICAL; OPTICS; OXYGEN; PHANTOMS, IMAGING; RATS; RATS, SPRAGUE-DAWLEY; SPECTROSCOPY, NEAR-INFRARED;

EID: 0036525875     PISSN: 10833668     EISSN: None     Source Type: Journal    
DOI: 10.1117/1.1463048     Document Type: Article

References (41)

1. A simple photoelectric colorimeter
2. The oximeter, an instrument for measuring continuously the oxygen saturation of arterial blood in man
3. Noninvasive infrared monitoring of cerebral and myocardial oxygen sufficiency and circulatory parameters
4. System for long-term measurement of cerebral blood and tissue oxygenation on newborn infants by near intra-red transillumination
5. Diagnostic imaging with light
6. Cognition-activated low frequency modulation of light absorption in human brain
7. Human visual cortical function during photic stimulation monitoring by means of near infrared spectoscopy
8. Near infrared spectroscopy (NIRS): A new tool to study hemodynamic changes during activation of brain function in human adults
9. Detection of dynamic changes in cerebral oxygenation coupled to neuronal function during metal work in man
10. Spatial and temporal analysis of human motor activity using non-invasive NIR topography
11. Visualizing human motor activity by using non-invasive optical topography
12. Non-invasive assessment of language dominance with near-infrared spectroscopic mapping
13. Non-invasive cerebral blood volume measurement during seizures using multichannel near infrared spectroscopic topography
14. Spontaneous oscillation of oxy- and deoxy-hemoglobin changes with a phase difference throughout the occipital cortex of newborn infants observed using non-invasive optical topography
15. Fast and localized event related optical signals (EROS) in the human occipetal cortex: Comparisons with the visual evoked potential and fMRI
16. Theoretical and experimental investigation of near infrared light propagation in a model of the adult head
17. A Monte Carlo investigation of optical pathlength in inhomogeneous tissue and its application to near-infrared spectroscopy
18. Spectroscopy and imaging with diffusing light
19. Cerebral and muscle oxygen saturation measurement by frequency-domain near-infra-red spectrometer
20. Time resolved reflectance and transmittance for the non-invasive measurement of tissue optical properties
21. Optical time of flight and absorbance imaging of biological media
22. Quantitative assessment of blood flow, blood volume, and blood oxygenation effects in functional magnetic resonance imaging
23. Quantitative capillary topography and blood flow in the cerebral cortex of cats: An in vivo microscopic study
24. Oxidative metabolism in muscle
25. Absolute quantification methods in tissue near infrared spectroscopy
26. Quantitative of cerebral blood volume in human infants by near infrared spectroscopy
27. Cerebral blood flow and oxygen consumption in the rat in hypoxic hypoxia
28. Cerebral hemodynamic effects of treatment with modified surfactant investigated by near infrared spectroscopy
29. Neonatal intensive care application of near infrared spectroscopy
30. Physiologic basis for BOLD MR signal changes due to neuronal stimulation: Separation of blood volume and magnetic susceptibility effects
31. Quantification of dynamic changes in cerebral venous oxygenation with MR phase imaging at 1.9 T
32. Dynamic functional imaging of relative cerebral blood volume during rat forepaw stimulation
33. Magnetic resonance evidence of organ hypoxia in a homozygous alpha-knockout of a transgenic mouse model for sickle cell disease
34. Noninvasive detection of skeletal muscle underperfusion with near-infrared spectroscopy in patients with heart failure
35. A simplified approach to characterize optical properties and blood oxygenation in tissue using continuous near infrared light
36. Quantification of time- and frequency-resolved optical spectra from the determination of tissue oxygenation
37. Functional near-infrared imager
38. Optical investigations of physiology: A study of intrinsic and extrinsic biomedical contrast