Integrated planar terahertz resonators for femtomolar sensitivity label-free detection of DNA hybridization

Applied Optics

Volumn 41, Issue 10, 2002, Pages 2074-2078

  Nagel, Michael ^a   Bolivar, Peter Haring ^a   Brucherseifer, Martin ^a   Kurz, Heinrich ^a   Bosserhoff, Anja ^a   Büttner, Reinhard ^a  

^a RWTH AACHEN UNIVERSITY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

DNA;

ARTICLE; ELECTROMAGNETIC FIELD; GENETICS; INSTRUMENTATION; NUCLEIC ACID HYBRIDIZATION; SENSITIVITY AND SPECIFICITY;

DNA; ELECTROMAGNETICS; NUCLEIC ACID HYBRIDIZATION; SENSITIVITY AND SPECIFICITY;

DNA; ELECTROMAGNETIC WAVES; ELECTROOPTICAL EFFECTS; IMAGE ANALYSIS; PULSED LASER APPLICATIONS; SIGNAL DETECTION; TIME DOMAIN ANALYSIS; ULTRAFAST PHENOMENA;

FEMTOMOLAR SENSITIVITY;

OPTICAL RESONATORS;

EID: 0036525867     PISSN: 1559128X     EISSN: 21553165     Source Type: Journal    
DOI: 10.1364/AO.41.002074     Document Type: Article

References (27)

1. R. Drmanac, S. Drmanac, Z. Strezoska, T. Paunesku, I. Labat, M. Zeremski, J. Snoddy, W. K. Funkhouser, B. Koop, and L. Hood, “DNA sequence determination by hybridization: astrategy for efficient large-scale sequencing,” Science 260, 1649-1653 (1993).
2. M. Chee, R. Yang, E. Hubbell, A. Berno, X. C. Huang, D. Stern, J. Winkler, D. J. Lockhart, M. S. Morris, and S. P. Fodor, “Accessing genetic information with high-density DNA arrays,” Science 274, 610-614 (1996).
3. R. J. Cho, M. Fromont-Racine, L. Wodicka, B. Feierbach, T. Stearns, P. Legrain, D. J. Lockhart, and R. W. Davis, “Parallel analysis of genetic selections using whole genome oligonucleotide arrays,” Proc. Natl. Acad. Sci. USA 95, 3752-3757 (1998).
4. H. Ozaki and L. W. McLaughlin, “The estimation of distances between specific backbone-labeled sites in DNA using fluorescence resonance energy transfer,” Nucleic Acids Res. 20, 5205-5214 (1992).
5. Z. Zhu, J. Chao, H. Yu, and A. S. Waggoner, “Directly labeled DNA probes using fluorescent nucleotides with different length linkers,” Nucleic Acids Res. 22, 3418-3422 (1994).
6. Z. Zhu and A. S. Waggoner, “Molecular mechanism controlling the incorporation of fluorescent nucleotides into DNA by PCR,” Cytometry 28, 206-211 (1997).
7. M. L. Larramendy, W. El-Rifai, and S. Knuutila, “Comparison of fluorescein isothiocyanate- and Texas red-conjugated nucleotides for direct labeling in comparative genomic hybridization,” Cytometry 31, 174-179 (1998).
8. G. S. Edwards, C. C. Davis, J. D. Saffer, and M. L. Swicord, “Resonant microwave absorption of selected DNA molecules,” Phys. Rev. Lett. 53, 1284-1287 (1984).
9. J. Hefti, A. Pan, and A. Kumar, “Sensitive detection method of dielectric dispersions in aqueous-based, surface-bound macro-molecular structures using microwave spectroscopy,” Appl. Phys. Lett. 75, 1802-1804 (1999).
10. H. J. Watts, D. Yeung, and H. Parkes, “Real-time detection and quantification of DNA hybridization by an optical biosensor,” Anal. Chem. 67, 4283-4289 (1995).
11. E. Souteyrand, J. P. Cloarec, J. R. Martin, C. Wilson, I. Lawrence, S. Mikkelsen, and M. F. Lawrence, “Direct detection of the hybridization of synthetic homo-oligomer DNA sequences by field effect,” J. Phys. Chem. B 101, 2980-2985 (1997).
12. E. Palecek, M. Fojta, M. Tomschik, and J. Wang, “Electrochemical biosensors for DNA hybridization and DNA damage,” Biosens. Bioelectron. 13, 621-628 (1998).
13. Y. Okahata, M. Kawase, K. Niikura, F. Ohtake, H. Furusawa, and Y. Ebara, “Kinetic measurements of DNA hybridization on an oligonucleotide-immobilized 27-MHz quartz crystal microbalance,” Anal. Chem. 10, 1288-1296 (1998).
14. H. Zhang, H. Tan, R. Wang, W. Wei, and S. Yao, “Immobilization of DNA on silver surface of bulk acoustic wave sensor and its application to the study of UV-C damage,” Anal. Chim. Acta 374, 31-38 (1998).
15. J. Fritz, M. K. Baller, H. P. Lang, H. Rothuizen, P. Vettiger, E. Meyer, H.-J. Güntherodt, Ch. Gerber, and J. K. Gimzewskil, “Translating biomolecular recognition into nanomechanics,” Science 288, 316-318 (2000).
16. M. Brucherseifer, M. Nagel, P. Haring Bolivar, H. Kurz, A. Bosserhoff, and R. Büttner, “Label-free probing of the binding state of DNA by time-domain terahertz sensing,” Appl. Phys. Lett. 77, 4049-4051 (2000).
17. L. L. Van Zandt and V. K. Saxena, “Millimeter-microwave spectrum of DNA: six predictions for spectroscopy,” Phys. Rev. A 39, 2672-2674 (1989).
18. W. Zhuang, Y. Feng, and E. W. Prohofsky, “Self-consistent calculation of localized DNA vibrational properties at a double-helix-single-strand junction with anharmonic potential,” Phys. Rev. A. 41, 7033-7042 (1990).
19. M. Bykhovskaia, B. Gelmont, T. Globus, D. L. Woolard, A. C. Samuels, T. H. Duong, and K. Zakrzewska, “Prediction of DNA far-IR absorption spectra based on normal mode analysis,” Theor. Chem. Acc. 106, 22-27 (2001).
20. H. Urabe and Y. Tominaga, “Low-lying collective modes of DNA double helix by Raman spectroscopy,” Biopolymers 21, 2477-2481 (1982).
21. S. Lindsay, S. A. Lee, J. W. Powell, T. Weidlich, C. Demarco, G. D. Lewen, and N. J. Tao, “The origin of the A to B transitions in DNA fibres and films,” Biopolymers 27, 1015-1043 (1988).
22. J. W. Powell, G. S. Edwards, L. Genzel, F. Kremer, A. Wittlin, W. Kubasek, and W. Peticolas, “Investigation of far-infrared vibrational modes in polynucleotides,” Phys. Rev. A 35, 3929-3939 (1987).
23. A. G. Markelz, A. Roitberg, and E. J. Heilweil, “Pulsed terahertz spectroscopy of DNA, bovine serum albumin and collagen between 0.1 and 2.0 THz,” Chem. Phys. Lett. 320, 42-48 (2000).
24. H. Urabe, and Y. Tominaga, “Low frequency Raman spectra of DNA,” J. Phys. Soc. Jpn. 50, 3543-3543 (1981).
25. M. Nagel, C. Meyer, H.-M. Heiliger, T. Dekorsy, H. Kurz, R. Hey, and K. Ploog, “Optical second-harmonic probe for ultrahigh frequency on-chip interconnects with benzocyclobutene,” Appl. Phys. Lett. 72, 1018-1020 (1998).
26. M. D. Janezic and J. Baker-Jarvis, “Full-wave analysis of a split-cylinder resonator for nondestructive permittivity measurements,” IEEE Trans. Microwave Theory Tech. 47, 2014-2020 (1999).
27. T. Pfeifer, H.-M. Heiliger, T. Loffler, C. Ohlhoff, C. Meyer, G. Lupke, H. G. Roskos, and H. Kurz, “Optoelectronic on-chip characterization of ultrafast electric devices: measurements techniques and applications,” IEEE J. Sel. Top. Quantum Electron. 2, 586-604 (1996)