Characterization of anti-phosphatidylcholine polyreactive natural autoantibodies from normal human subjects

Journal of Autoimmunity

Volumn 18, Issue 2, 2002, Pages 181-190

  Cabiedes, Javier ^a   Cabral, Antonio R ^a   López Mendoza, A Tamara ^a   Cordero Esperón, Hugo A ^a   Huerta, M Teresa ^a   Alarcón Segovia, Donato ^a  

^a INSTITUTO NACIONAL DE CIENCIAS MÉDICAS Y NUTRICIÓN SALVADOR ZUBIRÁN   (Mexico)

Author keywords

Anti phosphatidylcholine antibodies; Autoantibodies in normal human subjects; ELISA natural autoantibodies; Polyreactive autoantibodies

Indexed keywords

AUTOANTIBODY; AUTOANTIGEN; BROMELAIN; DOUBLE STRANDED DNA; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M; IMMUNOGLOBULIN M ANTIBODY; PHOSPHATIDIC ACID; PHOSPHATIDYLCHOLINE ANTIBODY; PHOSPHORYLCHOLINE; RHEUMATOID FACTOR; UNCLASSIFIED DRUG; VIMENTIN;

ANIMAL CELL; ANTIBODY DETECTION; ARTICLE; CONTROLLED STUDY; CROSS REACTION; DOT HYBRIDIZATION; ENZYME LINKED IMMUNOSORBENT ASSAY; FIBROBLAST; FLOW CYTOMETRY; FLUORESCENT ANTIBODY TECHNIQUE; HEP 2 CELL; HUMAN; HUMAN CELL; IMMUNOGLOBULIN BLOOD LEVEL; MOUSE; NONHUMAN; NORMAL HUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; WESTERN BLOTTING;

EID: 0036525508     PISSN: 08968411     EISSN: None     Source Type: Journal    
DOI: 10.1006/jaut.2001.0575     Document Type: Article

References (40)

1. Guilbert B., Dighiero G., Avrameas S. Naturally occurring antibodies against nine common antigens in human sera. I. Detection, isolation, and characterization. J. Immunol. 128:1982;2779-2787.
2. Avrameas S. Natural autoantibodies: from 'horror autotoxicus' to 'gnoti seuton'. Immunol. Today. 12:1991;154-159.
3. Boyden S.V. Natural antibodies and the immune response. Adv. Immunol. 5:1965;1-28.
4. George J., Shoenfeld Y. Natural Autoantibodies. Peters J.B., Shoenfeld Y. Autoantibodies. 1996;534-539 Elsevier, Amsterdam.
5. Lacroix-Desmazes S., Kaveri S.V., Mouthon L., Ayouba A., Malanchére E., Coutinho A., Kazatchinke M.D. Self-reactive antibodies (natural antibodies) in healthy individuals. J. Immunol. Methods. 216:1998;117-137.
6. Ochsenbein A.F., Zinkernagel R.M. Natural antibodies and complement link innate and acquired immunity. Immunol. Today. 21:2000;624-630.
7. Stewart J. Immunoglobulins did not arise in evolution to fight infection. Immunol. Today. 13:1992;396-399.
8. Poncet P., Kocher H.P., Pages J., Jaton J.C., Bussard A.E. Monoclonal autoantibodies against mouse red blood cells: A family of structurally restricted molecules. Mol. Immunol. 22:1985;541-551.
9. Kawaguchi S. Reactivity of mouse antibodies against bromelain-treated mouse erythrocytes with thrombin-treated mouse platelets. Immunology. 66:1989;335-338.
10. Kawaguchi S. Antiphospholipid antibodies reactive with bromelain-treated mouse erythrocytes in mice rats and rabbits. Int. Arch. Aller. Appl. Immunol. 96:1991;46-50.
11. Arnold L.W., Haughton G. Autoantibodies to phosphatidylcholine. The murine antibromelain RBC response. Ann. NY Acad. Sci. 651:1992;354-359.
12. Kawaguchi S. Phospholipid epitopes for mouse antibodies against bromelain-treated mouse erythrocytes. Immunology. 62:1987;11-16.
13. Reininger L., Shibata T., Shurmans S. Spontaneous production of anti-mouse red blood cell autoantibodies is independent of the polyclonal activation in NZB mice. Eur. J. Immunol. 20:1990;2405-2410.
14. Cabral A.R., Cabiedes J., Alarcón-Segovia D. Hemolytic anemia related to an IgM autoantibody to phosphatidylcholine that binds in vitro to stored and to bromelain-treated erythrocytes. J. Autoimmunity. 3:1990;773-787.
15. Cabral, A.R. Alarcón-Segovia, D. 1996, Bromelain-treated erythrocyte autoantibodies, Autoantibodies, J.B. PeterY. Shoenfeld, Elsevier, Amsterdam, 120, 215.
16. Cabral A.R., Cabiedes J., Alarcón-Segovia D. Hemolytic anemia (HA) in systemic lupus erythematosus (SLE) associates strongly with IgM anti-phosphatidylcholine antibodies (aPTC) (Abstract). Clin. Exp. Rheumatol. 8:1990;212.
17. Abuaf N., Laperche S., Rajoeley B., Carsique R., Descjamps A., Rouquette A.M., Barther C., Khaled Z., Marbot C., Saab N., Rozen J., Girard P.M., Rozenbaum W. Autoantibodies to phospholipids and to coagulations proteins in AIDS. Thromb. Haemost. 77:1997;856-861.
18. Casao M.A., Leiva J., Diaz R. Anti-phosphatidylcholine antibodies in patients with brucellosis. J. Med. Microbol. 47:1998;49-54.
19. Koike T., Maruyama N., Funkai H., Tomioka H., Yoshida S. Specificity of mouse hybridoma antibodies to DNA. II. phospholipid reactivity and biological false positive test for syphilis. Clin. Exp. Immunol. 57:1984;345-350.
20. 2-glycoprotein-I and their unmasking by heat. Clin. Exp. Rheumatol. 12:1994;123-127.
21. Towbin H., Staehelin T., Gordon J. Electrophoretic transfer of protein from SDS and acid/urea polyacrylamide gels to nitrocellulose sheets: procedure and some applications. PNAS. 76:1979;4350-4354.
22. Serban D., Pages J.M., Bussard A.E., Witz I.P. The participation of trimethylammonium in the mouse erythrocyte epitope recognized by monoclonal autoantibodies. Immunol. Lett. 3:1981;315-319.
23. Cabiedes J., Cabral A.R., Alarcón-Segovia D. Hidden antiphospholipid antibodies in normal human sera circulate as immune complexes whose antigen can be removed by heat, acid, hypermolar buffers or phospholipase treatments. Eur. J. Immunol. 28:1998;2108-2114.
24. Adib M., Ragimbeau J., Avrameas S., Ternynck T. IgG autoantibody activity in normal mouse serum is controlled by IgM. J. Immunol. 145:1990;3807-3813.
25. Sharma A., Isenberg D.A., Diamond B. Crossreactivity of human anti-dsDNA antibodies to phosphorylcholine: clues to their origin. J. Autoimmunity. 16:2001;479-484.
26. Mercolino T.J., Arnold L.W., Hawkins L.A., Haughton G. Normal mouse peritoneum contains a large population of Ly-1+ (CD5) B cells that recognize phosphatidyl choline. Relationship to cells that secrete hemolytic antibody specific for autologous erythrocytes. J. Exp. Med. 168:1988;687-698.
27. Tominaga A., Takaki S., Koyama N., Katoh S., Matsumoto R., Migita M., Hitoshi Y., Hosoya Y., Yamauchi S., Kanai Y., Miyazaki J.I., Usuku G., Yamamura K.I., Takatsu K. Transgenic mice expressing a B cell growth differentiation factor gene (Interleukin 5) develop eosinophilia and autoantibody production. J. Exp. Med. 173:1991;429-437.
28. Pennell C.A., Sheehan K.M., Brodeur P.H., Clarke S.H. Organization and expression of VH gene families preferentially expressed by Ly-1+ (CD5) B cells. Eur. J. Immunol. 19:1989;2115-2121.
29. Conger J.D., Sage H.J., Corley R.B. Diversity in the available repertoire of murine antibodies reactive with bromelain-treated isologous erytrocytes. J. Immunol. 143:1989;4044-4052.
30. Andrade L., Huetz F., Poncet P. Biased VH gene expression in murine CD5 B cells results from age-dependent cellular selection. Eur. J. Immunol. 21:1991;2017-2023.
31. Yoshida S., Castles J.J., Gershwin M.E. The pathogenesis of autoimmunity in New Zealand mice. Semin. Arthritis Rheum. 19:1990;224-242.
32. Hentati B., Payelle-Brogard B., Jouanne C., Avrameas S., Ternynck T. Natural autoantibodies are involved in the haemolytic anaemia of NZB mice. J. Autoimmunity. 7:1994;425-439.
33. Jenkins W.J., Marsh W.L. Autoimmune haemolytic anemia. Three cases with antibodies specifically active against stored red cells. Lancet. I:1961;16-18.
34. Oken M.M., Griffiths R.W., Williams R.C., Reimann B.E.F. Possible NZB syndrome in man. Arch. Intern. Med. 132:1973;237-240.
35. Favre H., Chatenlanat F., Miescher P.A. Autoimmune hematologic disease associated with infraclinical systemic lupus erythematosus in four patients. A human equivalent of the NZB mice. Am. J. Med. 66:1979;91-95.
36. Cooper M.R., Cohen H.J., Huntley C.C., Waite B.M., Spees L., Spurr C.L. A monoclonal IgM with antibody-like specificity for phospholipids in a patient with lymphoma. Blood. 43:1974;493-504.
37. Villarreal G.M., Alarcón-Segovia D., Villa A.R., Cabral A.R., Shoenfeld Y. Presence of a 16/6-related human anti-DNA common idiotype (SA1) in the serum of patients with primary antiphospholipid syndrome. J. Rheumatol. 18:1991;1537-1541.
38. Chen P., Liu M., Sinha S., Carson D.A. A 16/6 idiotype-positive anti-DNA is encoded by a conserved VH gene with no somatic mutation. Arthritis Rheum. 31:1988;1429-1431.
39. Velasquillo M.C., Alcocer-Varela J., Alarcón-Segovia D., Cabiedes J., Sánchez-Guerrero J. Some patients with primary antiphospholipid syndrome have increased circulating CD5+ B cells that correlate with levels of IgM antiphospholipid antibodies. Clin. Exp. Rheumatol. 9:1991;501-505.
40. Guzmán J., Cabral A.R., Cabiedes J., Pita-Ramírez L., Alarcón-Segovia D. Antiphospholipid antibodies in patients with idiopathic autoimmune haemolytic anemia. Autoimmunity. 18:1994;51-56.