A herpes simplex virus type 1 mutant with γ34.5 and LAT deletions effectively oncolyses human U87 glioblastomas in nude mice

Neurosurgery

Volumn 50, Issue 3, 2002, Pages 599-606

  Samoto, Ken ^a   Ehtesham, Moneeb ^a   Perng, Guey Chuen ^a,b   Hashizume, Kazuhiro ^a   Wechsler, Steven L ^a,b   Nesburn, Anthony B ^a,b   Black, Keith L ^a   Yu, John S ^a,c   Rutka, James T ^d   Kornblith, Paul L ^d   Piepmeier, Joseph M ^d   Glick, Roberta P ^d   Lichtor, Terry ^d   Parsa, Andrew T ^d   Bruce, Jeffrey N ^d  

^a BURNS AND ALLEN RESEARCH INSTITUTE   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c CEDARS SINAI MEDICAL CENTER   (United States)

^d NONE

Author keywords

Brain tumors; Glioma; Green fluorescent protein; Herpes simplex virus Type 1

Indexed keywords

ANTINEOPLASTIC AGENT; DM33; GANCICLOVIR; GENE PRODUCT; GREEN FLUORESCENT PROTEIN; LAT PROTEIN; ONCOLYTIC VIRUS; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER GRAFT; CONTROLLED STUDY; CYTOLYSIS; FEMALE; GENE DELETION; GLIOBLASTOMA; HERPES SIMPLEX VIRUS 1; MOUSE; NONHUMAN; NUDE MOUSE; PRIORITY JOURNAL; SAFETY; TUMOR VOLUME; VIRUS INFECTION; VIRUS REACTIVATION; VIRUS RECOMBINANT; VIRUS REPLICATION; VIRUS VIRULENCE;

ANIMALS; ANTIVIRAL AGENTS; BRAIN NEOPLASMS; CORPUS STRIATUM; FEMALE; GANCICLOVIR; GENE DELETION; GLIOBLASTOMA; GREEN FLUORESCENT PROTEINS; HERPESVIRUS 1, HUMAN; HUMANS; INDICATORS AND REAGENTS; INJECTIONS, INTRALESIONAL; INJECTIONS, INTRAPERITONEAL; LUMINESCENT PROTEINS; MICE; MICE, INBRED BALB C; MICE, NUDE; MUTATION; NEOPLASM TRANSPLANTATION; VIRAL PROTEINS; VIRUSES;

EID: 0036523974     PISSN: 0148396X     EISSN: None     Source Type: Journal    
DOI: 10.1097/00006123-200203000-00031     Document Type: Article

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