Early evolution of deficits in acute ischemic stroke: Mean transit time, relative blood volume, and relative blood flow

Journal of Stroke and Cerebrovascular Diseases

Volumn 11, Issue 2, 2002, Pages 66-71

  Phan, Thanh G ^a   Huston III, John ^a   Campeau, Norbert G ^a   Brown Jr , Robert D ^a   Fulgham, Jimmy R ^a   Wijdicks, Eelco F M ^a  

^a MAYO CLINIC   (United States)

Author keywords

Cerebral infarction; Diffusion abnormality; Ischemic stroke; Magnetic resonance imaging; Middle cerebral artery

Indexed keywords

FIBRINOLYTIC AGENT; NEUROPROTECTIVE AGENT;

ADULT; AGED; ARTICLE; BRAIN BLOOD FLOW; BRAIN BLOOD VOLUME; BRAIN INFARCTION; CEREBROVASCULAR ACCIDENT; CLINICAL ARTICLE; DIFFUSION WEIGHTED IMAGING; FEMALE; HUMAN; MAGNETIC RESONANCE ANGIOGRAPHY; MALE; MIDDLE CEREBRAL ARTERY OCCLUSION; PILOT STUDY; PRIORITY JOURNAL; PROSPECTIVE STUDY; RECANALIZATION; STROKE;

EID: 0036522479     PISSN: 10523057     EISSN: None     Source Type: Journal    
DOI: 10.1053/jscd.2002.126689     Document Type: Article

References (34)

1. Minematsu K, Yamaguchi T, Omae T. "Spectacular shrinking deficit": Rapid recovery from a major hemispheric syndrome by migration of an embolus. Neurology 1992;42:157-162.
2. Baird AE, Donnan GA, Austin MC, et al. Early reperfusion in the 'spectacular shrinking deficit' demonstrated by single-photon emission computed tomography. Neurology 1995;45:1335-1339.
3. Astrup J, Siesjo BK, Symon L. Thesholds in cerebral ischemia-The ischemic penumbra. Stroke 1981;12:723-725.
4. Symon L, Branston NM, Strong AJ, et al. The concepts of thresholds of ischaemia in relation to brain structure and function. J Clin Pathol Suppl (R Coll Pathol) 1977;11:149-154.
5. Ginsberg MD, Pulsinelli WA. The ischemic penumbra, injury thresholds, and the therapeutic window for acute stroke. Ann Neurol 1994;36:553-554.
6. Weinstein PR, Anderson GG, Telles DA. Neurological deficit and cerebral infarction after temporary middle cerebral artery occlusion in unanesthetized cats. Stroke 1986;17:318-324.
7. Takano K, Latour LL, Formato JE, et al. The role of spreading depression in focal ischemia evaluated by diffusion mapping. Ann Neurol 1996;39:308-318.
8. Hoehn-Berlage M, Norris DG, Kohno K, et al. Evolution of regional changes in apparent diffusion coefficient during focal ischemia of rat brain: The relationship of quantitative diffusion NMR imaging to reduction in cerebral blood flow and metabolic disturbances. J Cereb Blood Flow Metab 1995;15:1002-1011.
9. Loubinoux I, Volk A, Borredon J, et al. Spreading of vasogenic edema and cytotoxic edema assessed by quantitative diffusion and T2 magnetic resonance imaging. Stroke 1997;28:419-426.
10. Marchal G, Beaudouin V, Rioux P, et al. Prolonged persistence of substantial volumes of potentially viable brain tissue after stroke: A correlative PET-CT study with voxel-based data analysis. Stroke 1996;27:599-606.
11. 18F-fluoromisonidazole positron emission tomography after ischemic stroke. Ann Neurol 2000;48:228-235.
12. Heiss WD, Graf R, Wienhard K, et al. Dynamic penumbra demonstrated by sequential multitracer PET after middle cerebral artery occlusion in cats. J Cereb Blood Flow Metab 1994;14:892-902.
13. Baron JC, von Kummer R, del Zoppo GJ. Treatment of acute ischemic stroke. Challenging the concept of a rigid and universal time window. Stroke 1995;26:2219-2221.
14. Saccetti ML, Toni D, Fiorelli M, et al. The concept of combination therapy in acute ischemic stroke. Neurology 1997;49:S70-S74 (Suppl 4)
15. Baird AE, Warach S. Magnetic resonance imaging of acute stroke. J Cereb Blood Flow Metab 1998;18:583-609.
16. Sorensen AG, Copen WA, Ostergaard L, et al. Hyper-acute stroke: Simultaneous measurement of relative cerebral blood volume, relative cerebral blood flow, and mean tissue transit time. Radiology 1999;210:519-527.
17. Barber PA, Davis SM, Infeld B, et al. Spontaneous reperfusion after ischemic stroke is associated with improved outcome. Stroke 1998;29:2522-2528.
18. Barber PA, Darby DG, Desmond PM, et al. Prediction of stroke outcome with echoplanar perfusion- and diffusion-weighted MRI. Neurology 1998;51:418-426.
19. Schlaug G, Benfield A, Baird AE, et al. The ischemic penumbra: Operationally defined by diffusion and perfusion MRI. Neurology 1999;53:1528-1537.
20. Kidwell CS, Saver JL, Mattiello J, et al. Thrombolytic reversal of acute human cerebral ischemic injury shown by diffusion/perfusion magnetic resonance imaging. Ann Neurol 2000;47:462-469.
21. Ay H, Buonanno FS, Rordorf G, et al. Normal diffusion- weighted MRI during stroke-like deficits. Neurology 1999;52:1784-1792.
22. Tong DC, Yenari MA, Albers GW, et al. Correlation of perfusion- and diffusion-weighted MRI with NIHSS score in acute (< 6.5 hour) ischemic stroke. Neurology 1998;50:864-870.
23. Neumann-Haefelin T, Wittsack HJ, Wenserski F, et al. Diffusion- and perfusion-weighted MRI. The DWI/PWI mismatch region in acute stroke. Stroke 1999;30:1591-1597.
24. Beaulieu C, de Crespigny A, Tong DC, et al. Longitudinal magnetic resonance imaging study of perfusion and diffusion in stroke: Evolution of lesion volume and correlation with clinical outcome. Ann Neurol 1999;46:568-578.
25. Sorensen AG, Buonanno FS, Gonzalez RG, et al. Hyper-acute stroke: Evaluation with combined multisection diffusion-weighted and hemodynamically weighted echoplanar MR imaging. Radiology 1996;199:391-401.
26. Warach S, Dashe JF, Edelman RR. Clinical outcome in ischemic stroke predicted by early diffusion-weighted and perfusion magnetic resonance imaging: A preliminary analysis. J Cereb Blood Flow Metab 1996;16:53-59.
27. Schwamm LH, Koroshetz WJ, Sorensen AG, et al. Time course of lesion development in patients with acute stroke: Serial diffusion- and hemodynamic-weighted magnetic resonance imaging. Stroke 1998;29:2268-2276.
28. Rordorf G, Koroshetz WJ, Copen WA, et al. Regional ischemia and ischemic injury in patients with acute middle cerebral artery stroke as defined by early diffusion-weighted and perfusion-weighted MRI. Stroke 1998;29:939-943.
29. Barber PA, Davis SM, Darby DG, et al. Absent middle cerebral artery flow predicts the presence and evolution of the ischemic penumbra. Neurology 1999;52:1125-1132.
30. Kucharczyk J, Vexler ZS, Roberts TP, et al. Echo-planar perfusion-sensitive MR imaging of acute cerebral ischemia. Radiology 1993;188:711-717.
31. del Zoppo GJ, Schmid-Schonbein GW, Mori E, et al. Polymorphonuclear leukocytes occlude capillaries following middle cerebral artery occlusion and reperfusion in baboons. Stroke 1991;22:1276-1283.
32. Gyngell ML, Back T, Hoehn-Berlage M, et al. Transient cell depolarization after permanent middle cerebral artery occlusion: An observation by diffusion-weighted MRI and localized 1H-MRS. Magn Reson Med 1994;31:337-341.
33. Fieschi C, Argentino C, Lenzi GL, et al. Clinical and instrumental evaluation of patients with ischemic stroke within the first six hours. J Neurol Sci 1989;91:311-321.
34. Toni D, Fiorelli M, Zanette EM, et al. Early spontaneous improvement and deterioration of ischemic stroke patients. A serial study with transcranial Doppler ultrasonography. Stroke 1998;29:1144-1148.