Melatonin fails to modulate immune parameters influenced by calorie restriction in aging Fischer 344 rats

Experimental Biology and Medicine

Volumn 227, Issue 3, 2002, Pages 201-207

  Pahlavani, Mohammad A ^a,b   Vargas, Daniel A ^a,b   Evans, Ted R ^a   Shu, Jian Hua ^a   Nelson, James F ^a  

^a UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO   (United States)

^b SOUTH TEXAS VETERANS HEALTH CARE SYSTEM   (United States)

Author keywords

Caloric restriction; Immunomodulation, aging; Melatonin; Rat

Indexed keywords

CD3 ANTIGEN; CELL MARKER; CONCANAVALIN A; GAMMA INTERFERON; INTERLEUKIN 2; LIPOPOLYSACCHARIDE; MELATONIN; THYMIDINE;

AGED; AGING; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CALORIC RESTRICTION; CELL PROLIFERATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; DNA SYNTHESIS; ENZYME LINKED IMMUNOSORBENT ASSAY; FLOW CYTOMETRY; FLUOROMETRY; IMMUNOMODULATION; LONG TERM CARE; NATURAL KILLER CELL; NONHUMAN; RAT; RAT STRAIN; SPLEEN CELL; T LYMPHOCYTE; T LYMPHOCYTE SUBPOPULATION;

ANIMALIA;

EID: 0036521771     PISSN: 00379727     EISSN: None     Source Type: Journal    
DOI: 10.1177/153537020222700308     Document Type: Article

References (45)

1. Maestroni GJ, Conti A, Lissoni P. Colony-stimulating activity and hematopoieticrescue from cancer chemotherapy compounds are in duced by melatonin via endogenous interleukin 4. Cancer Res 54:4740-4743, 1994.
2. Molina-Carballo A, Munoz-Hoyos A, Reiter RJ, Sanchez-Forte M, Moreno-Madrid F, Rufo-Campos M. Utility of high doses of melatonin as adjunctive anticonvulsant therapy in a child with severe myoclonic epilepsy: two years experience. J Pineal Res 23:97-105, 1997.
3. Reiter RJ, Reiter MN, Hattori A, Yaga K, Herbert DC, Barlow-Walden L. The pinealmelatonin rhythm and its regulation by light in a subterranean rodent, the valley pocket gopher (Thomomys bottae). J Pineal Res 16:145-153, 1994.
4. Kotler M, Rodriguez C, Sainz RM, Antolin I, Menendez-Pelaez A. Melatoninincreases gene expression for antioxidant enzymes in rat brain cortex. J Pineal Res 24:83-89, 1998.
5. Steinhilber D, Brungs M, Werz O, Wiesenberg I, Danielsson C, Kahlen JP. Thenuclear receptor for melatonin represses 5-lipoxygenase gene expression in human B lymphocytes. J Biol Chem 270:7037-7040, 1995.
6. Mayo JC, Sainz RM, Uria H, Antolin I, Esteban MM, Rodriguez C. Inhibition of cellproliferation: a mechanism likely to mediate the prevention of neuronal cell death bymelatonin. J Pineal Res 25:12-18, 1998.
7. Conti A, Maestroni GJ. The clinical neuroimmunotherapeutic role of melatonin inoncology. J Pineal Res 19:103-110, 1995.
8. Maestroni GJ, Conti A, Pierpaoli W. Role of the pineal gland in immunity: circadiansynthesis and release of melatonin modulates the antibody response and antagonizes the immunosuppressive effect of corticosterone. J Neuroimmunol 13:19-30, 1986.
9. Maestroni GJ, Conti A, Pierpaoli W. Role of the pineal gland in immunity: II. Melatoninenhances the antibody response via an opiatergic mechanism. Clin Exp Immunol 68:384-391, 1987.
10. Maestroni GJ. The immunoneuroendocrine role of melatonin. J Pineal Res 14:1-10, 1993.
11. Reiter RJ. Oxidative processes and antioxidative defense mechanisms in the agingbrain. FASEB J 9:526-533, 1995.
12. Reiter RJ, Tan DX, Poeggeler B, Menendez-Pelaez A, Chen LD, Saarela S. Melatonin as a free radical scavenger: implications for aging and age-relateddiseases. Ann N Y Acad Sci 719:1-12, 1994.
13. Gilad E, Cuzzocrea S, Zingarelli B, Salzman AL, Szabo C. Melatonin is a scavenger of peroxynitrite. Life Sci 60:L169-L174, 1997.
14. Pierpaoli W, Regelson W. Pineal control of aging: effect of melatonin and pineal grafting on aging mice. Proc Natl Acad Sci U S A 91:787-791, 1994.
15. Oaknin-Bendahan S, Anis Y, Nir I, Zisapel N. Effects of long-term administration of melatonin and a putative antagonist on the ageing rat. Neurol Rep 6:785-788, 1995.
16. Caroleo MC, Doria G, Nistico, G. Melatonin restores immunodepression in aged and cyclophosphamide-treated mice. Ann NY Acad Sci 719:343-352, 1994.
17. Mocchegiani E, Bulian D, Santarelli L, Tibaldi A, Muzzioli M, Pierpaoli W, Fabris, N. The immunoreconstituting effect of melatonin or pineal grafting and its relation to zinc pool in aging mice. J Neuroimmunol 53:189-201, 1994.
18. Angeli A, Gatti G, Sartori ML, Del Ponte D, Cerignola R. Effect of exogenous melatonin on human natural killer (NK) cell activity. An approach to the immunomodulatory role of the pineal gland. In: Gupta D, Attanasio A, Reiter RJ, Eds. The Pineal Gland and Cancer. Tuε̈bingen, Müller and Bass, pp145-156, 1988.
19. Pioli C, Caroleo MC, Nistico G, Doria G. Melatonin increases antigen presentation and amplifies specific and non specific signals for T-cell proliferation. Int J Immunopharmacol 15:463-468, 1993.
20. Maestroni GJ, Conti A, Pierpaoli W. Role of the pineal gland in immunity. III. Melatonin antagonizes the immunosuppressive effect of acute stress via an opiatergic mechanism. Immunology 63:465-469, 1988.
21. Pawlikowski M, Lyson K, Kunert-Radek J, Stepien H. Effect of benzodiazepines on the proliferation of mouse spleen lymphocytes in vitro. J Neural Transm 73:161-166, 1988.
22. Provinciali M, Di Stefano G, Bulian D, Stronati S, Fabris N. Long-term melatonin supplementation does not recover the impairment of natural killer cell activity and lymphocyte proliferation in aging mice. Life Sci 61:857-864, 1997.
23. Pahlavani MA, Harris MD. In vitro effects of melatonin on mitogen-induced lymphocyte proliferation and cytokine expression in young and old rats. Immunopharmacol Immunotoxicol 19:327-337, 1997.
24. Arzt ES, Fernandez-Castelo S, Finocchiaro LM, Criscuolo ME, Diaz A, Finkielman S, Nahmod VE. Immunomodulation by indoleamines: serotonin and melatonin action on DNA and interferon-γ synthesis by human peripheral blood mononuclear cells. J Clin Immunol 8:513-520, 1988.
25. Masoro EJ, McCarter RM. Dietary restriction as a probe of mechanisms of senescence. Ann Rev Gerontol 10:183-197, 1990.
26. Masoro EJ. Dietary restriction. Exp Gerontol 30:291-308, 1995.
27. Masoro EJ. Caloric restriction. Aging 10:173-184, 1998.
28. Pahlavani MA. Does caloric restriction alter IL-2 transcription? Front Biosci 3:d125:d135, 1998.
29. Weindruch R, Gottesman SR, Walford RL. Modification of age-related immune decline in mice dietarily restricted from or after midadulthood. Proc Natl Acad Sci U S A 79:898-902, 1982.
30. Weindruch R, Devens BH, Raff HV, Walford RL. Influence of dietary restriction and aging on natural killer cell activity in mice. J Immunol 130:993-996, 1983.
31. Sandyk R. Melatonin supplements for aging. Int J Neurosci 87:219-224, 1996.
32. +) T cells in F344 rats. Mech Ageing Dev 74:171-176, 1994.
33. McCarthy KF, Hale ML, Fehnel PL. Rat colony-forming unit spleen is OX7 positive, W3/13 positive, OX1 positive, and OX22 negative. Exp Hematol 13:847-854, 1985.
34. Pahlavani MA, Cheung TH, Chesky JA, Richardson A. Influence of exercise on the immune function of rats of various ages. J Appl Physiol 64:1997-2001, 1988.
35. Manfredi B, Sacerdote P, Bianchi M, Locatelli L, Veljic-Radulovic J, Panerai AE. Evidence for an opioid inhibitory effect on T cell proliferation. J Neuroimmunol 44:43-48, 1993.
36. Pahlavani MA, Harris MD. Effect of dehydroepiandrosterone on mitogen-induced lymphocyte proliferation and cytokine production in young and old F344 rats. Immunol Lett 47:9-14, 1995.
37. Provinciali M, Di Stefano G, Fabris N. Optimization of cytotoxic assay by target cell retention of the fluorescent dye carboxyfluorescein diacetate (CFDA) and comparison with conventional 51CR release assay. J Immunol Methods 155:19-24, 1992.
38. Pahlavani MA. Caloric restriction and immunosenescence: a current perspective. Front Biosci 5:D580-D587, 2000.
39. Venkatraman J, Attwood VG, Turturro A, Hart RW, Fernandes G. Maintenance of virgin T cells and immune function by food restriction during aging in ling-lived B6D2F1 female mice. Aging Immunol Infec Dis 5:13-25, 1994.
40. Cristina MC, Daniela F, Giuseppe N. Melatonin as immunomodulatory in immunodeficient mice. Immunopharmacology 23:81-89, 1992.
41. Lucas LC, Guan-Jie C, Maria CL. Melatonin induced increase in γ-interferon production by murine splenocytes. Immunol Lett 33:123-126, 1992.
42. Kolitz JE, Welte K, Sykora KW, Mertelsmann R. Interleukin 2: a review. Arzneimittelforschung 35:1607-1615. 1985.
43. Patrini G, Sacerdote P, Fuzio D, Manfredi B, Parolaro D. Regulation of immune functions in rat splenocytes after acute and chronic in vivo treatment with CP-55,940, a synthetic cannabinoid compound. J Neuroimmunol 80:143-148, 1997.
44. Sze SF, Liu WK, Ng TB. Stimulation of murine splenocytes by melatonin and methoxytryptamine. J Neural Transm Gen Sect 94:115-126, 1993.
45. Atre D, Blumenthal EJ. Melatonin: immune modulation of spleen cells in young, middle aged and senescent mice. Mech Ageing Dev 103:255-268, 1998.