Reversal of pulmonary hypertension associated with plexiform lesions in congenital heart disease: A case report

Pediatric Cardiology

Volumn 23, Issue 2, 2002, Pages 182-185

  Epting, C L ^a   Wolfe, R R ^a   Abman, S H ^a   Deutsch, G H ^a   Ivy, D ^a  

^a CHILDREN S HOSPITAL   (United States)

Author keywords

Atrial natriuretic peptide; Congenital heart disease; Nitric oxide; Patent ductus arteriosus; Pulmonary hypertension

Indexed keywords

NITRIC OXIDE; VASODILATOR AGENT;

ARTERY DISEASE; ARTICLE; CASE REPORT; CLINICAL FEATURE; CONGENITAL HEART DISEASE; DISEASE ASSOCIATION; DISEASE COURSE; DISEASE SEVERITY; FEMALE; FOLLOW UP; HUMAN; HUMAN TISSUE; LUNG BIOPSY; LUNG INJURY; LUNG VASCULAR RESISTANCE; PATENT DUCTUS ARTERIOSUS; PULMONARY HYPERTENSION; SCHOOL CHILD; SURGICAL TECHNIQUE; TREATMENT OUTCOME; TREATMENT PLANNING; LUNG; PATHOLOGY; PATHOPHYSIOLOGY; PRESCHOOL CHILD; VASCULAR RESISTANCE;

CHILD, PRESCHOOL; DUCTUS ARTERIOSUS, PATENT; FEMALE; FOLLOW-UP STUDIES; HUMANS; HYPERTENSION, PULMONARY; LUNG; TREATMENT OUTCOME; VASCULAR RESISTANCE;

EID: 0036518027     PISSN: 01720643     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00246-001-0044-9     Document Type: Article

References (19)

1. Anderson R, Levy A, Naeye R, Tabakin B (1967) Rapidly progressing pulmonary vascular obstructive disease. Association with ventricular septal defects. Am J Cardiol 19:854-858
2. Atz AM, Adatial I, Lock JE, Wessel DL (1999) Combined effects of nitric oxide and oxygen during acute pulmonary vasodilator testing. J Am Coll Cardiol 33:813-819
3. Bernen M, Beghetti M, Spahr-Schopfer I, Oberhansli I, Friedli B (1996) Inhaled nitric oxide to test the vasodilator capacity of the pulmonary vascular bed in children with long-standing pulmonary hypertension and congenital heart disease. Am J Cardiol 77:53-535
4. Haworth SG, Reid L (1978) A morphometric study of regional variation in lung structure in infants with pulmonary hypertension and congenital cardiac defect. A justification of lung biopsy. Br Heart J 40:825-831
5. Heath D, and Edwards J (1958) The pathology of hypertensive pulmonary vascular disease. Circulation 18:533-537
6. Horvath KA, Burke RP, Collins J Cohn LH (1992) Surgical treatment of adult atrial septal defect: early and long-term result. J Am Coll Cardiol 20:1156-1159
7. Ivy DD, Kinsella JP, Wolfe RR, Abman SH (1996) Atrial natriuretic peptide and nitric oxide in children with pulmonary hypertension after surgical repair of congenital heart disease. Am J Cardiol 77:102-105
8. Ivy D, Neish S, Abman S (1998) Regulation of the pulmonary circulation. In: Garson A, Bricker A, Fisher D, Neish S (eds) The Science and Practice of Pediatric Cardiology. Williams & Wilkens, Baltimore, pp 329-347
9. Kidd L, Driscoll DJ, Gersony WM, et al (1993) Second natural history study of congenital heart defects. Results of treatment of patients with ventricular septal defects. Circulation 87:I38-I51
10. Lee SD, Shroyer KR, Markham NE, et al (1998) Monoclonal endothelial cell proliferation is present in primary but not secondary pulmonary hypertension. J Clin Invest 101:927-934
11. Newfeld EA, Paul MM, Muster AJ, Idriss FS (1974) Pulmonary vascular disease in complete transposition of the great arteries: a study of 200 patients. Am J Cardiol 34:75-82
12. Rabinovitch M (2001) Pathology of pulmonary hypertension. Prog in Pediatr Cardiol 12:223-247
13. Rabinovitch M (1999) Pulmonary hypertension: pathophysiology as a basis for clinical decision making. J Heart Lung Transplant 18:1041-1053
14. Rabinovitch M, Harworth SG, Castaneda AR, Nadas AS, Reid LM (1978) Lung biopsy in congenital heart disease: a morphometric approach to pulmonary vascular disease. Circulation 58:1107-1122
15. Rabinovitch M, Keane JF, Norwood WI, Castaneda AR. Reid L (1984) Vascular structure in lung tissue obtained at biopsy correlated with pulmonary hemodynamic findings after repair of congenital heart defects. Circulation 69:655-667
16. Wagenvoort CA (1994) Plexogenic arteriopathy. Thorax 49:S39-S45
17. Wagenvoort CA, Wagenvoort N (1974) Pathology of the Eisenmenger syndrome and primary pulmonary hypertension. Adv Cardiol 11:123
18. Wagenvoort CA, Wagenvoort N, Draulans-Noe Y (1984) Reversibility of plexogenic pulmonary arteriopathy following banding of the pulmonary artery. J Thorac Cardiovasc Surg 87:876-886
19. Yeager ME, Halley GR, Golpon HA, Voelkel NF, Tuder RM (2001) Microsatellite instability of endothelial cell growth and apoptosis genes within plexiform lesions in primary pulmonary hypertension. Circ Res 88:E2-E11