Genetics and gene expression in pulmonary hypertension: Parker B. Francis lecture

Chest

Volumn 121, Issue 3, 2002, Pages 46S-50S

  Loyd, James E ^a  

^a VANDERBILT UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BONE MORPHOGENETIC PROTEIN 2; BONE MORPHOGENETIC PROTEIN 4; BONE MORPHOGENETIC PROTEIN 6; OSTEOGENIC PROTEIN 1; PROTEIN SERINE THREONINE KINASE; TRANSFORMING GROWTH FACTOR BETA; BMP2 PROTEIN, HUMAN; BMPR2 PROTEIN, HUMAN; BONE MORPHOGENETIC PROTEIN; BONE MORPHOGENETIC PROTEIN RECEPTOR 2; MICROSATELLITE DNA;

CONFERENCE PAPER; DISEASE COURSE; DISEASE SEVERITY; DNA MICROARRAY; ENZYME ACTIVATION; FAMILY HISTORY; GENE EXPRESSION; GENE MUTATION; GENE SEQUENCE; GENETIC HETEROGENEITY; GENETIC LINKAGE; GENETIC SUSCEPTIBILITY; GENETICS; GENOTYPE; HUMAN; LIGAND BINDING; MORTALITY; PRIORITY JOURNAL; PROGENY; PULMONARY HYPERTENSION; VERTICAL TRANSMISSION; ADULT; ARTICLE; FEMALE; LUNG; MALE; METABOLISM; MIDDLE AGED; MUTATION; PATHOLOGY; PEDIGREE;

ADULT; BONE MORPHOGENETIC PROTEIN RECEPTORS, TYPE II; BONE MORPHOGENETIC PROTEINS; FEMALE; GENE EXPRESSION; HUMANS; HYPERTENSION, PULMONARY; LINKAGE (GENETICS); LUNG; MALE; MICROSATELLITE REPEATS; MIDDLE AGED; MUTATION; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PEDIGREE; PROTEIN-SERINE-THREONINE KINASES; TRANSFORMING GROWTH FACTOR BETA;

EID: 0036517156     PISSN: 00123692     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Conference Paper

References (16)

1. Primary pulmonary hypertension: A national prospective study
2. Sporadic primary pulmonary hypertension is associated with germ-line mutations of the gene encoding BMPR-II, a receptor member of the TGF-β family
3. Genetic anticipation and abnormal gender ratio at birth in familial primary pulmonary hypertension
4. Bone morphogenetic proteins: Multifunctional regulators of vertebrate development
5. Heterogeneity of pathologic lesions in familial PPH
6. Mutations in the gene for bone morphogenetic protein receptor II as a cause of primary pulmonary hypertension in a large kindred
7. Localization of the gene for familial primary pulmonary hypertension to chromosome 2q31-32
8. Mapping of familial primary pulmonary hypertension locus (PPH1) to chromosome 2q31-q32
9. Heterozygous germline mutations in a TGF-β receptor, BMPR2, are the cause of familial primary pulmonary hypertension
10. Familial primary pulmonary hypertension (gene PPH1) is caused by mutations in the bone morphogenetic protein receptor-II gene
11. The family of bone morphogenetic proteins
12. A gene for primary pulmonary hypertension
13. BMPR2 haploinsufficiency as the inherited molecular mechanism for primary pulmonary hypertension
14. Gene expression patterns in the lungs of patients with primary pulmonary hypertension: A gene microarray analysis
15. Monoclonal endothelial cell proliferation is present in primary but not secondary pulmonary hypertension
16. Microsatellite instability of endothelial cell growth and apoptosis genes within plexiform lesions in primary pulmonary hypertension