K-Ras mediates cytokine-induced formation of E-cadherin-based adherens junctions during liver development

EMBO Journal

Volumn 21, Issue 5, 2002, Pages 1021-1030

  Matsui, Takaaki ^a   Kinoshita, Taisei ^a   Morikawa, Yoshihiro ^a   Tohya, Kazuo ^a   Katsuki, Motoya ^a   Ito, Yoshiaki ^a   Kamiya, Akihide ^a   Miyajima, Atsushi ^a  

^a UNIVERSITY OF TOKYO   (Japan)

Author keywords

E cadherin; Homophilic adhesion; K Ras; Liver organogenesis

Indexed keywords

CATENIN; CYTOKINE; ONCOSTATIN M; RETROVIRUS VECTOR; UVOMORULIN;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BINDING SITE; CELL ADHESION; CELL DIFFERENTIATION; CELL JUNCTION; CELLULAR DISTRIBUTION; CONTROLLED STUDY; EMBRYO; EPITHELIUM; FETUS; GENE EXPRESSION; KNOCKOUT MOUSE; LIVER CELL CULTURE; LIVER DEVELOPMENT; MOUSE; NONHUMAN; ONCOGENE H RAS; ONCOGENE K RAS; ONCOGENE N RAS; ORGANOGENESIS; PRIORITY JOURNAL; REGULATORY MECHANISM; SIGNAL TRANSDUCTION;

ADHERENS JUNCTIONS; ANIMALS; BETA CATENIN; CADHERINS; CELL DIFFERENTIATION; CELLS, CULTURED; CYTOSKELETAL PROTEINS; DEXAMETHASONE; ENZYME ACTIVATION; FETAL PROTEINS; GENES, RAS; GENETIC COMPLEMENTATION TEST; HEPATOCYTES; LIVER; MEMBRANE PROTEINS; MICE; MICE, KNOCKOUT; ONCOSTATIN M; PEPTIDES; PHENOTYPE; PHOSPHOPROTEINS; PROTEIN STRUCTURE, TERTIARY; PROTO-ONCOGENE PROTEINS C-RAF; PROTO-ONCOGENE PROTEINS P21(RAS); RECOMBINANT FUSION PROTEINS; SIGNAL TRANSDUCTION; TRANS-ACTIVATORS;

ANIMALIA; UNIDENTIFIED RETROVIRUS;

EID: 0036500155     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/21.5.1021     Document Type: Article

References (47)

1. Cellular redistribution of protein tyrosine phosphatases LAR and PTPσ by inducible proteolytic processing
2. Activation of SRF-regulated chromosomal templates by Rho-family GTPases requires a signal that also induces H4 hyperacetylation
3. Mechanism for transition from initial to stable cell-cell adhesion: Kinetic analysis of E-cadherin-mediated adhesion using a quantitative adhesion assay
4. The small GTPases Rho and Rac are required for the establishment of cadherin-dependent cell-cell contacts
5. Role of cytokine signaling molecules in erythroid differentiation of mouse fetal liver hematopoietic cells: Functional analysis of signaling molecules by retrovirus-mediated expression
6. A primary requirement for nodal in the formation and maintenance of the primitive streak in the mouse
7. Origins of cell polarity
8. Two signals are necessary for cell proliferation induced by a cytokine receptor gp130: Involvement of STAT3 in anti-apoptosis
9. Hepatic specification of the gut endoderm in vitro: Cell signaling and transcriptional control
10. Cell adhesion: The molecular basis of tissue architecture and morphogenesis
11. Rho GTPases and the actin cytoskeleton
12. A polybasic domain or palmitoylation is required in addition to the CAAX motif to localize p21ras to the plasma membrane
13. Signaling mechanisms through gp130: A model of the cytokine system
14. Retroviral gene transfer of signaling molecules into murine fetal hepatocytes defines distinct roles for the STAT3 and fas pathways during hepatic development
15. K-ras is an essential gene in the mouse with partial functional overlap with N-ras
16. Fetal liver development requires a paracrine action of oncostatin M through the gp130 signal transducer
17. Exogenous C2-ceramide activates c-fos serum response element via Rac-dependent signalling pathway
18. Efficient screening of retroviral cDNA expression libraries
19. K-ras is essential for the development of the mouse embryo
20. Cell density-dependent regulation of hepatic development by a gp130-independent pathway
21. Regulation of cell-cell adhesion of MDCK cells by Cdc42 and Rac1 small GTPases
22. Association between a transmembrane protein tyrosine phosphatase and the cadherin-catenin complex
23. Cloning and characterization of a specific receptor for mouse oncostatin M
24. New insights into the interaction of Ras with the plasma membrane
25. Definitive hematopoiesis is autonomously initiated by the AGM region
26. In vitro expansion of murine multipotential hematopoietic progenitors from the embryonic aorta-gonad-mesonephros region
27. Cell binding function of E-cadherin is regulated by the cytoplasmic domain
28. The roles of catenins in the cadherin-mediated cell adhesion: Functional analysis of E-cadherin-α catenin fusion molecules
29. Expressed recombinant cadherins mediate cell sorting in model systems
30. Applications of retrovirus-mediated expression cloning
31. Altered cell adhesion activity by pervanadate due to the dissociation of α-catenin from the E-cadherin catenin complex
32. Activation of both MAP kinase and phosphatidylinositide 3-kinase by Ras is required for hepatocyte growth factor/scatter factor-induced adherens junction disassembly
33. Involvement of the tyrosine kinase fer in cell adhesion
34. Regulation of E-cadherin/catenin association by tyrosine phosphorylation
35. Dominant-negative caveolin inhibits H-Ras function by disrupting cholesterol-rich plasma membrane domains
36. Cell lineages and oval cell progenitors in rat liver development
37. Temporal changes in the expression and distribution of adhesion molecules during liver development and regeneration
38. Caveolin, cholesterol and Ras signalling
39. Identification of ZO-1: A high molecular weight polypeptide associated with the tight junction (zonula occludens) in a variety of epithelia
40. Gp130 and the interleukin-6 family of cytokines
41. Regulation of cell-cell adhesion by fac and rho small G proteins in MDCK cells
42. The cadherins: Cell-cell adhesion molecules controlling animal morphogenesis
43. Morphogenetic roles of classic cadherins
44. Functional reconstitution of the mouse oncostatin M receptor: Molecular cloning of the mouse OSM receptor β subunit
45. The murine N-ras gene is not essential for growth and development
46. Activation of the c-fos serum response element by phosphatidyl inositol 3-kinase and tho pathways in HeLa cells
47. Bone morphogenetic protein-4 is required for mesoderm formation and patterning in the mouse