Intracellular cAMP increases during the positive inotropism induced by androgens in isolated left atrium of rat

European Journal of Pharmacology

Volumn 438, Issue 1-2, 2002, Pages 45-52

  Velasco, Lucía ^a   Sánchez, Manuel ^a   Rubín, José Manuel ^a   Hidalgo, Agustín ^a   Bordallo, Carmen ^b   Cantabrana, Begoa ^a  

^a UNIVERSITY OF OVIEDO   (Spain)

^b DEPARTAMENTO DE BIOQUÍMICA Y BIOLOGÍA MOLECULAR   (Spain)

Author keywords

Androgen; Atrium, rat; cAMP

Indexed keywords

5BETA ANDROSTANOLONE; ANDROGEN; ANDROSTANOLONE; ATENOLOL; BOVINE SERUM ALBUMIN; CYCLIC AMP; ISOBUTYLMETHYLXANTHINE; ISOPRENALINE; RESERPINE;

ANIMAL TISSUE; ARTICLE; BINDING ASSAY; CELL LEVEL; CONCENTRATION RESPONSE; CONJUGATION; CONTROLLED STUDY; DRUG BINDING; DRUG EFFECT; DRUG INHIBITION; DRUG MECHANISM; HALF LIFE TIME; HEART LEFT ATRIUM; HORMONE ACTION; INOTROPISM; MALE; MOLECULAR INTERACTION; NONHUMAN; ORGAN CULTURE; PRIORITY JOURNAL; PROTEIN DETERMINATION; RAT; REGULATORY MECHANISM; TRANSCRIPTION REGULATION;

1-METHYL-3-ISOBUTYLXANTHINE; ADRENERGIC BETA-AGONISTS; ADRENERGIC BETA-ANTAGONISTS; ANDROGENS; ANIMALS; ATENOLOL; ATRIAL FUNCTION; BINDING, COMPETITIVE; CATTLE; CYCLIC AMP; DIHYDROALPRENOLOL; DIHYDROTESTOSTERONE; DOSE-RESPONSE RELATIONSHIP, DRUG; HEART ATRIA; ISOPROTERENOL; MALE; MEMBRANES; MYOCARDIAL CONTRACTION; PHOSPHODIESTERASE INHIBITORS; RATS; RATS, WISTAR; RESERPINE; SERUM ALBUMIN, BOVINE; TRITIUM;

EID: 0036497104     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-2999(02)01300-6     Document Type: Article

References (31)

1. Estrogen action via the cAMP signalling pathway: Stimulation of adenylate cyclase and cAMP-regulated gene transcription
2. Beta-adrenergic stimulation of c-fos gene expression in the mouse submandibular gland
3. Increased expression of c-jun, but not retinoic acid receptor beta, is associated with F9 teratocarcinoma stem cell differentiation induced by polyamine depletion
4. Increases of ornithine decarboxylase activity in the positive inotropism induced by androgens in isolated left atrium of rat
5. Single step method of RNA isolation by guanidium thiocyanate phenol chloroform extraction
6. Testosterone causes direct relaxation of rat thoracic aorta
7. Multiple actions of steroid hormones - A focus on rapid, non-genomic effects
8. Efectos de 5α- y 5β-dihidrotestosterona en aurícula izquierda aislada de rata in vitro
9. Effects of androgens and antiandrogens on the inotropism induced by ouabain and isoproterenol on the left atrium of the rat in vitro
10. Unoccupied β-adrenoceptor-induced adenylyl cyclase stimulation in turkey erythrocyte membranes
11. 1-adrenoceptor stimulation inhibits the isoproterenol-induced effects on myocardial contractility and protein phosphorylation
12. Alpha- and beta-adrenergic stimulation induces distinct patterns of immediate early gene expression in neonatal rat myocardial cells. fos/jun expression is associated with sarcomere assembly; Egr-1 induction is primarily an alpha 1-mediated response
13. Polyamines mediate androgenic stimulation of calcium fluxes and membrane transport in rat heart myocytes
14. Transcriptional regulation by cAMP and its receptor protein
15. Transcriptional regulation of the tyrosine hydroxylase gene by glucocorticoid and cyclic AMP
16. Hormone response domains in gene transcription
17. Diazepam potentiates the positive inotropic effect of isoprenaline in rat ventricle strips: Role of cyclic AMP
18. Temporal changes in insulin-like growth factor I, c-fos, and c-jun gene expression during hyperplastic kidney growth in weanling rats
19. Regulation of c-jun gene expression by cAMP in HL-60 myeloid leukemia cells
20. Regulation of c-fos expression in adipose and muscle tissue of diabetic rats
21. cAMP analog antagonists of cAMP action
22. Polyamines modulate transcription but not posttranscription of c-myc and c-jun in IEC-6 cells
23. Positive inotropism induced by androgens in isolated left atrium of rat: Evidence for a cAMP-dependent transcriptional mechanism
24. Multihormonal regulation of phosphoenolpyruvate carboxykinase gene transcription. The dominant role of insulin
25. Reverse intrinsic activity of antagonists on G protein-coupled receptors
26. Expression of c-jun, Jun B, Jun D and cAMP response element binding protein by Schwann cells and their precursors in vivo and in vitro
27. Inhibition of T lymphocyte activation by cAMP is associated with down-regulation of two parallel mitogen-activated protein kinase pathways, the extracellular signal-related kinase and c-jun N-terminal kinase
28. Decreased expression of protooncogenes c-fos, c-myc, and c-jun following polyamine depletion in IEC-6 cells
29. 2+ dynamics, contractility, or phospholamban phosphorylation
30. Testosterone relaxes rabbit coronary arteries and aorta