Urinary 1-hydroxypyrene as a biomarker of internal dose of polycyclic aromatic hydrocarbons in carbon black workers

Annals of Occupational Hygiene

Volumn 46, Issue 2, 2002, Pages 229-235

  Tsai, Perng Jy ^a   Shieh, Hong Yong ^a,b   Lee, Wen Jhy ^a   Chen, Hsiao Lung ^a   Shih, Tung Sheng ^b  

^a NATIONAL CHENG KUNG UNIVERSITY   (Taiwan)

^b INSTITUTE OF OCCUPATIONAL SAFETY AND HEALTH   (Taiwan)

Author keywords

1 hydroxypyrene; Biological monitoring; Carbon black; Polycyclic aromatic hydrocarbons; Pyrene

Indexed keywords

BIOMARKERS; CARCINOGENS; POLYCYCLIC AROMATIC HYDROCARBONS; REGRESSION ANALYSIS; AROMATIC COMPOUNDS; AROMATIC HYDROCARBONS; CARBON; HYDROCARBONS; LINEAR REGRESSION; PELLETIZING; PYRENE;

REGRESSION COEFFICIENTS;

HEALTH CARE; CARBON BLACK;

1 HYDROXYPYRENE; BIOLOGICAL MARKER; CARBON; POLYCYCLIC AROMATIC HYDROCARBON; 1-HYDROXYPYRENE; PYRENE DERIVATIVE;

ADULT; AGE DISTRIBUTION; ARTICLE; BODY MASS; CIGARETTE SMOKING; CONTROLLED STUDY; CORRELATION ANALYSIS; ENVIRONMENTAL EXPOSURE; FEMALE; HUMAN; INHALATION; LINEAR REGRESSION ANALYSIS; MAJOR CLINICAL STUDY; MALE; OCCUPATIONAL EXPOSURE; OCCUPATIONAL HEALTH; OCCUPATIONAL TOXICOLOGY; PARTICLE SIZE; PRIORITY JOURNAL; SEX DIFFERENCE; SMOKING HABIT; URINALYSIS; URINE LEVEL; AIR POLLUTANT; CHEMISTRY; ENVIRONMENTAL MONITORING; EXPOSURE; MATERIALS; MONITORING; REGRESSION ANALYSIS; URINE;

1-HYDROXYPYRENE; BACKGROUND INFORMATION; BIOLOGICAL MONITORING; CARCINOGENIC PAHS; INHALABLE PARTICLES; MULTIPLE LINEAR REGRESSION ANALYSIS; REGRESSION COEFFICIENT; WORKERS' EXPOSURES;

ADULT; AIR POLLUTANTS, OCCUPATIONAL; BIOLOGICAL MARKERS; CARBON; ENVIRONMENTAL MONITORING; FEMALE; HUMANS; INHALATION EXPOSURE; MALE; MANUFACTURED MATERIALS; MONITORING, PHYSIOLOGIC; OCCUPATIONAL EXPOSURE; POLYCYCLIC HYDROCARBONS, AROMATIC; PYRENES; REGRESSION ANALYSIS;

EID: 0036490713     PISSN: 00034878     EISSN: None     Source Type: Journal    
DOI: 10.1093/annhyg/mef017     Document Type: Article

References (24)

1. Attfield MD, Hewett P. (1992) Exact expressions for the bias and variance of estimators of the mean of a lognormal distribution. Am Ind Hyg Assoc J; 53: 423-35.
2. Buchet JP, Gennart JP, Mercado-Calderon F, Delavignette JP, Cupers L, Lauwery R. (1992) Evaluation of exposure to polycyclic aromatic hydrocarbons in a coke production and graphite electrode manufacturing plants: assessment of urinary excretion of 1-hydroxypyrene as a biological indicator of exposure. Br J Ind Med; 49: 761-8.
3. Flenklach M, Clary DW, Yuan T, Gardine CW, Stein SE. (1988) Production of polycyclic aromatic hydrocarbons in chlorine containing environments. Combust Sci Technol; 74: 283-92.
4. Gardiner K, Trethowan WN, Harrington JM, Calvert IA, Glass DC. (1992a) Occupational exposure to carbon black in its manufacture. Ann Occup Hyg; 36: 477-96.
5. Giardiner K, Hale KA, Calvert IA, Rice C, Harrington JM. (1992b) The suitability of the urinary metabolite 1-hydroxypyrene as an index of polynuclear aromatic hydrocarbon bio-availability from workers exposed to carbon black. Ann Occup Hyg; 36: 681-8.
6. Gardiner K, Calver IA, van Tongeren MJA, Harrington JM. (1996) Occupational exposure to carbon black in its manufacture: data from 1987-1992. Ann Occup Hyg; 40: 65-77.
7. IARC. (1987) IARC monographs on the evaluation of the carcinogenic risk of chemicals to humans, supplement 7. Lyons: International Agency for Research on Cancer.
8. ISO. (1990) ISO 8996: Ergonomics-determination of metabolic heat production. Geneva: International Standard Organization.
9. Jongeneelen FJ, Anzion BM, Henderson PTh. (1987) Determination of hydroxlated metabolites of polycyclic aromatic hydrocarbons in urine. J Chromatogr; 413: 227-32.
10. Jongeneelen FJ, Scheepers PJT, Groenendijk A, Van Aerts LA, Anzion RBM, Bos RP, Veestra SJ. (1988) Airborne concentrations, skin contamination, and urinary metabolite excretion of polycyclic aromatic hydrocarbons among paving workers exposed to coal tar derived road tars. Am Ind Hyg Assoc J; 49: 600-7.
11. Jongeneelen FJ, van Leeuwen FE, Oosterink S, Anzion RBM, Van der Loop F, Bos RP, Van Veen HG. (1990) Ambient and biological monitoring of coke oven workers: determination of internal dose of PAHs. Br J Ind Med; 47: 454-61.
12. London MA, Boiano JM, Lee SA. (1989) Exposure assessment of 3,3′-dicholorobenzidine. (DCB) at two chemical plants. Appl Ind Hyg; 4: 101-4.
13. NIOSH. (1994) Manual of analytical methods 5506: polynuclear aromatic hydrocarbons by HPLC. Washington DC: US Department of Health and Human Services, National Institute for Occupational Safety and Health.
14. Nisbet C, LaGoy P. (1992) Toxic equivalency factors. (TEFs) for polycyclic aromatic hydrocarbons. (PAHs). Regul Toxicol Pharmacol; 16: 290-300.
15. Ny ET, Heederik H, Kromhout H, Jongeneelen F. (1993) The relationship between polycyclic aromatic hydrocarbons in air and in urine of workers in a Soderbeg potroom. Am Ind Hyg Assoc J; 54: 277-84.
16. Poliski I. (1999) Carbon black: the state of art. Modern Paint Coat; 89: 40-1.
17. Robertson JM, Smith RG. (1994) Carbon black. In Patty's industrial hygiene and toxicology. New York: John Wiley & Sons.
18. Tsai P-J, Shieh HY, Lee WJ, Lai SO. (2001a) Characteristics of the exposure profiles for workers exposed to airborne dusts and polycyclic aromatic hydrocarbons. (PAHs) in the carbon black manufacturing industry. J Occup Health; 43: 118-28.
19. Tsai P-J, Shieh HY, Lee WJ, Lai SO. (2001b) Health-risk assessment for workers exposure to polycyclic aromatic hydrocarbons in a carbon black manufacturing industry. Sci Total Environ; 278: 137-50.
20. US EPA. (1992) Dermal exposure assessment: principles and applications. Washington DC: US Environmental Protection Administration, EPA/600/8-91/011B.
21. Van Rooij GM, Bodelier-Bade MM, Jogeneelen FJ. (1993) Estimation of individual dermal and respiratory uptake of polycyclic aromatic hydrocarbons in 12 coke oven workers. Br J Ind Med; 50: 623-32.
22. Viau C, Vyskocil A, Martel L. (1995) Background urinary 1-hydroxypyrene levels in non-occupational exposed individual in the province of Quebec, Canada, and comparison with it excretion in workers exposed to PAH mixtures. Sci Total Environ; 163: 191-4.
23. WHO. (1986) World Health Organization field surveys of exposure to pesticide protocol. Toxicol Lett; 33: 223-35.
24. Wolff RK, Sun JD, Barr EB, Rothenbergs J, Yeh HC. (1989) Lung retention and binding of. (14C)-1 nitropyrene when inhaled by F334 rats as a pure aerosol or adsorbed to carbon black particles. J Toxicol Environ Health; 26: 309-25.