Bone marrow transplantation: A new strategy for intractable diseases

Drugs of Today

Volumn 38, Issue 2, 2002, Pages 103-111

  Ikehara, Susumu ^a  

^a KANSAI MEDICAL UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

AUTOANTIBODY; THROMBOPOIETIN;

ALLOGENIC BONE MARROW TRANSPLANTATION; ANIMAL MODEL; APLASTIC ANEMIA; AUTOIMMUNE DISEASE; BONE MARROW TRANSPLANTATION; CELL FUNCTION; CHRONIC GLOMERULONEPHRITIS; CONTROLLED STUDY; CROHN DISEASE; GRAFT REJECTION; GRAFT VERSUS HOST REACTION; HEMATOLOGIC DISEASE; HEMATOPOIETIC STEM CELL; IDIOPATHIC THROMBOCYTOPENIC PURPURA; IMMUNE DEFICIENCY; IMMUNE FUNCTION TEST; IMMUNE RESPONSE; INSULIN DEPENDENT DIABETES MELLITUS; LEUKEMIA; MAJOR HISTOCOMPATIBILITY COMPLEX; MESENCHYMOMA; METABOLIC DISORDER; MONKEY; MOUSE; MULTIPLE SCLEROSIS; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; PORTAL VEIN BLOOD FLOW; RADIATION DOSE; REVIEW; RHEUMATOID ARTHRITIS; SYSTEMIC LUPUS ERYTHEMATOSUS; T LYMPHOCYTE; TREATMENT OUTCOME; ALLOTRANSPLANTATION; ANIMAL; AUTOTRANSPLANTATION; HUMAN; MURPHY ROTHS LARGE LYMPHOPROLIFERATIVE MOUSE; PHYSIOLOGY; STROMA CELL;

ANIMAL; AUTOIMMUNE DISEASES; BONE MARROW TRANSPLANTATION; HUMAN; MICE; MICE, INBRED MRL LPR; STROMAL CELLS; SUPPORT, NON-U.S. GOV'T; THROMBOPOIETIN; TRANSPLANTATION, AUTOLOGOUS; TRANSPLANTATION, HOMOLOGOUS; ANIMALS; HUMANS;

EID: 0036488580     PISSN: 16993993     EISSN: 16994019     Source Type: Journal    
DOI: 10.1358/dot.2002.38.2.820106     Document Type: Review

References (30)

1. Rationale for bone marrow transplantation in the treatment of autoimmune diseases
2. Prevention of type I diabetes in nonobese diabetic mice by allogeneic bone marrow transplantation
3. Treatment of type I diabetes mellitus in nonobese diabetic mice by transplantation of allogeneic bone marrow and pancreatic tissue
4. (NZW × BXSB)F1 mouse. A new model of idiopathic thrombocytopenic purpura
5. Long-term observations of autoimmune-prone mice treated for autoimmune disease by allogeneic bone marrow transplantation
6. Effects of bone marrow transplantation on antiphospholipid antibody syndrome in murine lupus mice
7. Bone marrow transplantation as a strategy for treatment of noninsulin-dependent diabetes mellitus in KK-Ay mice
8. Focal glomerulonephritis is a stem cell disorder
9. Organ-specific and systemic autoimmune diseases originate from defects in hematopoietic stem cells
10. Distinct qualitative differences between normal and abnormal hemopoietic stem cells in vivo and in vitro
11. Requirement of donor-derived stromal cells in the bone marrow for successful allogeneic bone marrow transplantation: Complete prevention of recurrence of autoimmune diseases in MRL/MP-Ipr/Ipr mice by transplantation of bone marrow plus bone (stromal cells) from the same donor
12. A new strategy for treatment of autoimmune diseases in chimeric resistant MRL/Ipr mice
13. Successful liver allografts in mice by combination with allogeneic bone marrow transplantation
14. Intra-bone marrow injection of allogeneic bone marrow cells: A powerful new strategy for treatment of intractable autoimmmune diseases in MRL/Ipr mice
15. Major histocompatibility complex restriction between hematopoietic stem cells and stromal cells in vivo
16. Production of hemopoietic stem cell-chemotactic factor by bone marrow stromal cells
17. Involvement of the K and I regions of the H-2 complex in resistance to hemopoietic allografts
18. Humoral and cell-mediated immune response in fully allogeneic bone marrow chimera in mice
19. Tolerance, immunocompetence, and secondary disease in fully allogeneic radiation chimeras
20. Immune function in fully allogeneic mouse bone marrow chimeras
21. Evidence for migration of donor bone marrow stromal cells into recipient thymus after bone marrow transplantation plus bone grafts; a role of the stromal cells in positive selection
22. Fate of allogeneic or syngeneic cells in intravenous or portal vein injection: Possible explanation for the mechanism of tolerance induction by portal vein injection
23. Induction of donor-specific T cell anergy by portal venous injection of allogeneic cells
24. A strategy for organ allografts without using immunosuppressants or irradiation
25. Treatment of intractable autoimmune diseases in MRL/Ipr mice using a new strategy for allogeneic bone marrow transplantation
26. Crucial role of donor-derived stromal cells in successful treatment for intractable autoimmune diseases in MRL/Ipr mice by BMT via the portal vein
27. Successful allogeneic bone marrow transplantation (BMT) by injection of bone marrow cells via portal vein: Stromal cells as BMT-facilitating cells
28. Intraosseous infusions
29. Intraosseous compared to intractable infusion of allogeneic bone marrow
30. A new method for bone marrow cell harvesting