Stability and plasticity of developing synapses in hippocampal neuronal cultures

Journal of Neuroscience

Volumn 22, Issue 3, 2002, Pages 775-781

  Woodward Hopf, F ^a   Waters, Jack ^b   Mehta, Samar ^c   Smith, Stephen J ^d  

^a UNIVERSITY OF CALIFORNIA SAN FRANCISCO   (United States)

^b MAX PLANCK INSTITUTE FOR MEDICAL RESEARCH   (Germany)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Activity; FM 1 43; Hippocampus; NMDA receptor; Plasticity; Synaptogenesis

Indexed keywords

FLUORESCENT DYE; FM 1 43; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; SYNAPSIN I; SYNAPTOPHYSIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; EMBRYO; FLUORESCENCE; HIPPOCAMPUS; IMMUNOCYTOCHEMISTRY; IMMUNOHISTOCHEMISTRY; NERVE CELL CULTURE; NERVE CELL PLASTICITY; NONHUMAN; PRESYNAPTIC NERVE; PRIORITY JOURNAL; RAT; SYNAPSE VESICLE; SYNAPTOGENESIS;

EID: 0036470113     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.22-03-00775.2002     Document Type: Article

References (34)

1. Quantitative analysis of cadherin-catenin-actin reorganization during development of cell-cell adhesion
2. Assembly of presynaptic active zones from cytoplasmic transport packets
3. Rat hippocampal neurons in low-density culture
4. Long-term depression in the hippocampus
5. Activity-dependent fluorescent staining and destaining of living motor nerve terminals
6. Synaptic modifications in cultured hippocampal neurons: Dependence on spike timing, synaptic strength, and postsynaptic cell type
7. Distributed synaptic modification in neural networks induced by patterned stimulation
8. A synaptic model of memory: Longterm potentiation in the hippocampus
9. Alterations in synaptic strength preceding axon withdrawal
10. Axon withdrawal during synapse elimination at the neuromuscular junction is accompanied by disassembly of the postsynaptic specialization and withdrawal of Schwann cell processes
11. Dynamics of synaptic vesicles in cultured spinal cord neurons in relationship to synaptogenesis
12. Retrograde signaling in the development and modification of synapses
13. The distribution of synapsin I and synaptophysin in hippocampal neurons developing in culture
14. Assembly of new individual excitatory synapses: Time course and temporal order of synaptic molecule recruitment
15. Synaptic activity and the construction of cortical circuits
16. Synaptic vesicle dynamics in living cultured hippocampal neurons visualized with CY3-conjugated antibodies directed against the lumenal domain of synaptotagmin
17. The development of ocular dominance columns in normal and visually deprived monkeys
18. Synapse elimination and indelible memory
19. Activity differentially regulates the surface expression of synaptic AMPA and NMDA glutamate receptors
20. Cyclic AMP induces functional presynaptic boutons in hippocampal CA3-CA1 neuronal cultures
21. Regulation of synaptic efficacy by coincidence of postsynaptic APs and EPSPs
22. Heterogeneous release properties of visualized individual hippocampal synapses
23. Mechanism of synapse disassembly at the developing neuromuscular junction
24. Activity regulates the synaptic localization of the NMDA receptor in hippocampal neurons
25. The kinetics of synaptic vesicle recycling measured at single presynaptic boutons
26. Vesicle pool mobilization during action potential firing at hippocampal synapses
27. Potentiation of evoked vesicle turnover at individually resolved synaptic boutons
28. Optical detection of a quantal presynaptic membrane turnover
29. Quantitative ultrastructural analysis of hippocampal excitatory synapses
30. Potassium ion- and nitric oxide-induced exocytosis from populations of hippocampal synapses during synaptic maturation in vitro
31. Molecular and functional diversity at synapses of individual neurons in vitro
32. Binocular impulse blockade prevents the formation of ocular dominance columns in cat visual cortex
33. Structure and function of the synapsins
34. Evidence for a role of dendritic filopodia in synaptogenesis and spine formation