Diazepam binding inhibitor (DBI) reduces testosterone and estradiol levels in vivo

Life Sciences

Volumn 70, Issue 11, 2002, Pages 1317-1323

  Dong, Erbo ^a   Matsumoto, Kinzo ^a   Watanabe, Hiroshi ^a  

^a UNIVERSITY OF TOYAMA   (Japan)

Author keywords

Benzodiazepine receptors; Central nervous system; DBI (diazepam binding inhibitor); Gonadal hormones

Indexed keywords

DIAZEPAM BINDING INHIBITOR; ESTRADIOL; FLUMAZENIL; TESTOSTERONE;

ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DOWN REGULATION; DRUG EFFECT; ENZYME IMMUNOASSAY; ESTRADIOL BLOOD LEVEL; FEMALE; GABAERGIC SYSTEM; HYPOTHALAMUS HYPOPHYSIS ADRENAL SYSTEM; IN VIVO STUDY; MALE; MOUSE; NONHUMAN; TESTOSTERONE BLOOD LEVEL;

ANIMALS; DIAZEPAM BINDING INHIBITOR; DOSE-RESPONSE RELATIONSHIP, DRUG; DOWN-REGULATION; DRUG ANTAGONISM; ESTRADIOL; FEMALE; FLUMAZENIL; GABA MODULATORS; INJECTIONS, INTRAVENTRICULAR; MALE; MICE; MICE, INBRED STRAINS; RECEPTORS, GABA-A; TESTOSTERONE;

EID: 0036469121     PISSN: 00243205     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0024-3205(01)01502-8     Document Type: Article

References (27)

1. Role of DBI in brain and its posttranslational processing products in normal and abnormal behavior
2. Diazepam binding inhibitor (DBI): A peptide with multiple biological actions
3. Flumazenil reverses the decrease in the hypnotic activity of pentobarbital by social isolation stress: Are endogenous benzodiazepine receptor ligands involved?
4. Involvement of diazepam binding inhibitor and its fragment octadecaneuropeptide in social isolation stress-induced decrease in pentobarbital sleep in mice
5. Role of the peripheral-type benzodiazepine receptor and the polypeptide diazepam binding inhibitor in steroidogenesis
6. A receptor: Ligand binding, chloride transport and behavior
7. A receptors in the rat
8. Effects of benzodiazepine agonist exposure on corticotropin-releasing factor content and hormonal stress responses: Divergent responses in male and ovariectomized female rats
9. Permissive role of brain allopregnanolone content in the regulation of pentobarbital-induced righting reflex loss
10. Neuroendocrinology and pathophysiology of stress system
11. Acute effects of triazolam in women: Relationships with progesterone, estradiol and allopregnanolone
12. Effect of oestrogen and testosterone implants on psychological disorders in the climacteric
13. Estrogen control of central neurotransmission: Effect on mood, mental state, and memory
14. Neuroendocrinological investigations during sleep deprivation in depression. I. Early morning levels of thyrotropin, TH, cortisol, prolactin, LH, FSH, estradiol, and testosterone
15. Diazepam-binding inhibitor. A brain neuropeptide present in human spinal fluid: Studies in depression, schizophrenia, and Alzheimer's disease
16. Diazepam-binding inhibitor and corticotropin-releasing hormone in cerebrospinal fluid
17. Pharmacological effects produced by intrcerbral injection of drugs in the conscious mouse
18. Gamma-aminobutyric acid effects on pituitary gonadotropin secretion
19. The effects of intraventricular injection γ-aminobutyric acid (GABA) on prolactin and gonadotropin release in conscious female rats
20. Interactions between GABAergic and serotonergic systems with excitatory amino acid neurotransmission in the hypothalamic control of gonadotropin secretion in prepubertal female rats
21. Diazepam-binding inhibitor: A neuropeptide located in selected neuronal populations of rat brain
22. Ontogeny of diazepam-binding inhibitor-related peptides (Endozepines) in the rat brain
23. Diazepam binding inhibitor (DBI) gene expression in the brains of socially isolated and group-housed mice
24. A receptors in the rat pituitary
25. Peripheral-type benzodiazepine receptors in endocrine organs: Autoradiographic localization in rat pituitary, adrenal, and testis
26. Dual effect of electrochemical stimulation of the medial preoptic area on the release of LH: Possible neurotransmitter involvement
27. Reduction of luteinizing hormone secretion induced by long-term feed restriction in male rats is associated with increased expression of GABA-synthesizing enzymes without alterations of GnRH gene expression