Photodegradation studies on Lacidipine in solution: Basic experiments with a cis-trans reversible photoequilibrium under UV-A radiation exposure

Journal of Pharmaceutical and Biomedical Analysis

Volumn 27, Issue 5, 2002, Pages 803-812

  De Filippis, P ^b   Bovina, E ^a   Da Ros, L ^b   Fiori, J ^a   Cavrini, V ^a  

^a UNIVERSITY OF BOLOGNA   (Italy)

^b GSK   (Italy)

Author keywords

cis trans photoequilibrium; Lacidipine; Liquid chromatography; Photostability

Indexed keywords

ACETONE; ALCOHOL; DICHLOROMETHANE; DIHYDROPYRIDINE DERIVATIVE; HEXANE; LACIDIPINE; SOLVENT;

CIS ISOMER; CIS TRANS ISOMERISM; CONCENTRATION (PARAMETERS); CONFERENCE PAPER; DRUG DEGRADATION; DRUG ISOLATION; DRUG SOLUTION; DRUG STABILITY; FLOW RATE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HYPERTENSION; PHOTODEGRADATION; PRIORITY JOURNAL; RADIATION EXPOSURE; RADIOSENSITIVITY; SPECTRAL SENSITIVITY; ULTRAVIOLET A RADIATION;

CALCIUM CHANNEL BLOCKERS; DIHYDROPYRIDINES; DRUG STABILITY; PHARMACEUTICAL SOLUTIONS; PHOTOCHEMISTRY; ULTRAVIOLET RAYS;

EID: 0036468854     PISSN: 07317085     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0731-7085(01)00505-2     Document Type: Conference Paper

References (10)

1. Is the photodecomposition of drug predictable?
2. Photochemistry of drugs: An overview and practical problems
3. ICH Harmonised Tripartite Guideline Q1B "Stability testing: Photostability testing of new drug substances and products", Appendix to: A. Albini, E. Fasani, Photochemistry of Drugs: An overview and practical problems
4. Medicinal photochemistry: An introduction with attention to kinetic aspects