Measuring TCDD equivalents in environmental samples with the micro-EROD assay: Comparison with HRGC/HRMS data

Bulletin of Environmental Contamination and Toxicology

Volumn 68, Issue 1, 2002, Pages 111-117

  Li, W ^a   Wu, W Z ^a   Xu, Y ^a   Li, L ^a   Schramm, K W ^b   Kettrup, A ^b  

^a INSTITUTE OF HYDROBIOLOGY   (China)

^b INSTITUTE OF EPIDEMIOLOGY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

2,3,7,8 TETRACHLORODIBENZO PARA DIOXIN; CYTOCHROME P450 1A1; DIOXIN; ETHOXYRESORUFIN DEETHYLASE; POLYCHLORINATED DIBENZODIOXIN;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BIOASSAY; CHINA; ENVIRONMENTAL MONITORING; ENZYME ACTIVITY; ENZYME ASSAY; FISH; FLY ASH; GAS CHROMATOGRAPHY; GERMANY; HEPATOMA CELL; LIVER TOXICITY; MASS SPECTROMETRY; NONHUMAN; RAT; SEDIMENT;

CYTOCHROME P-450 CYP1A1; ENVIRONMENTAL MONITORING; ENVIRONMENTAL POLLUTANTS; GAS CHROMATOGRAPHY-MASS SPECTROMETRY; IMMUNOENZYME TECHNIQUES; SENSITIVITY AND SPECIFICITY; TETRACHLORODIBENZODIOXIN;

ANIMALIA;

EID: 0036461003     PISSN: 00074861     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00128-001-0226-4     Document Type: Article

References (15)

1. Babich H, Borenfreund E (1986) Structure-activity relationship (SAR) models established in vitro with the neutral red cytotoxicity assay. Toxicol in Vitro 00: 1-7
2. Devito MJ, Birnbaum LS (1994) Toxicology of dioxins and related chemicals, in dioxins and health (A. Schechter,Ed.). Plenum, New York, p139-162
3. Donato MT, Gomez-Lechon MJ, Castlell JV (1993) A microassay for measuring cytochrome P4501A1 and P450 1B1 activities in intact human and rat hepatocytes cultured on 96-well plates. Anal Biochem 213: 29-33
4. Hahn ME, Woodward BL, Stegeman JJ, Kennedy SW (1996) Rapid assessment of induce cytochrome P4501A protein and catalytic activity in fish hepatoma cells grown in multiwell plates: response to TCDD, TCDF, and two planar PCBs. Environ Toxicol Chem 15: 582-591
5. Hanberg A, Strahlberg M, Georgellis A, de Wit C, Ahlborg UG (1991) Swedish dioxin survey: envalution of the H4IIE bioassay for screening environmental samples for dioxin-like enzyme induction. Pharmacol Toxicol 69: 442-449
6. Kennedy SW, Lorenzen A, James CA, Collins BT (1993) Ethoxyresorufin-O-deethylase and porphyrin analysis in chicken embroy hepatocyte cultures with a fluoresecence multiwell reader. Anal Biochem 211: 102-112
7. Kennedy SW, Jones SP, Bastien LJ (1995) Efficient analysis of cytochrome P4501A catalytic activity, porphyrins, and total proteins in chicken embryo hepatocyte cultures with a fluorescence plate reader. Anal Biochem 226: 362-370
8. Murk AJ, Leonards PEG, Bulder AS, Jonas AS, Rozemeijer MJC, Denison MS, Koeman JH, Brouwer A (1997) The CALUX (chemical-activated luciferase expression) assay adapted and validated for measuring TCDD equivalents in blood plasma. Environ Toxicol Chem 16: 1583-1589
9. Roscher E, Wiebel FJ (1992) Genotoxicity of 1,3- and 1,6-dinitropyrene: induction of micronuclei in a panel of mammalian test cell lines. Mutat Res 278: 11-17
10. Safe S (1990) Polychlorinated biphenyls (PCBs), dibenzo-p-dioxins (PCDDs), dibenzofurans (PCDFs), and related compounds: environmental and mechanistic considerations which support the development of toxic equivalency factors (TEFs). Crit Rev Toxicol 21: 51-88
11. Safe S (1993) Toxicology, structure-function relationships, human and environmental health impacts of polychlorinated biphenyls (PCBs): progress and problems. Environ Health Perspect 101: 317-322
12. Smith PK, Krohn RJ, Hermanson GT, Malia AK, Gartner FH, Prouanzano MD (1985) Measurement of protein using bicinchoninic acid. Anal Biochem 150: 76-85
13. Tillitt DE, Ankley GT, Giesy JP (1991) Characterization of the H4IIE rat hepatoma cell bioassay as a tool for assessing toxic potency of planar halogenated hydrocarbons in environmental samples. Environ Sci Technol 25: 87-92
14. Wu WZ, Schwirzer SMG, Schramm KW, Wiebel FJ, Xu Y, Zhang YY, Yediler A Kettrup A (1996) Induction of ethoxyresorufin O-deethylase (EROD) as indicator of potentially harmful effects for dioxin-like compounds in environmental samples of Ya-Er Lake area, China. Fresenius Environ Bull 5: 374-379
15. Wu WZ, Schramm K-W, Henkelmann B, Xu Y, Yediler A, Kettrup A (1997) PCDD/Fs, PCBs, HCHs and HCB in sediments and soil of Ya-Er Lake area in China: results on residual levels and correlation to the organic carbon and the particle size. Chemosphere 34: 191-202