Minute mixed ductal-endocrine carcinoma of the pancreas with predominant intraductal growth

Pathology International

Volumn 52, Issue 11, 2002, Pages 740-746

  Terada, Tadashi ^a   Kawaguchi, Masaharu ^a   Furukawa, Kazuo ^a   Sekido, Yasutomo ^b   Osamura, Yoshiyuki ^b  

^a Shizuoka Municipal Shimizu Hospital   (Japan)

^b TOKAI UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Minute cancer; Mixed ductal endocrine carcinoma; Pancreas; Pancreatic ducts

Indexed keywords

CARCINOEMBRYONIC ANTIGEN; CHROMOGRANIN A; ENZYME PRECURSOR; PANCREAS ENZYME; SYNAPTOPHYSIN;

ACUTE DISEASE; ADULT; ARTICLE; CANCER GROWTH; CANCER SIZE; CASE REPORT; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; ENDOSCOPY; ENZYME ANALYSIS; ENZYME BLOOD LEVEL; HISTOLOGY; HUMAN; HUMAN TISSUE; IMAGING; IMMUNOREACTIVITY; JAPAN; MALE; NEUROENDOCRINE SYSTEM; PANCREAS CARCINOMA; PANCREAS DUCT; PANCREATITIS; PANCREATOGRAPHY; PARASITE; PRIORITY JOURNAL;

ADULT; CA-19-9 ANTIGEN; CARCINOEMBRYONIC ANTIGEN; CARCINOMA, ISLET CELL; CARCINOMA, PANCREATIC DUCTAL; CHROMOGRANIN A; CHROMOGRANINS; HUMANS; KERATINS; MALE; PANCREATIC NEOPLASMS; SYNAPTOPHYSIN; TREATMENT OUTCOME; TUMOR MARKERS, BIOLOGICAL;

EID: 0036459389     PISSN: 13205463     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1440-1827.2002.01416.x     Document Type: Article

References (35)

1. Slack JMW. Developmental biology of the pancreas. Development 1995; 121: 1569-1580.
2. Kloppel G, Solcia E, Longnecker DS, Capella C, Sobin LH. Histological typing of tumours of the exocrine pancreas. In: World Health Organization: International Histological Classification of Tumours, 2nd Edn. Springer, New York, 1996; 15-21.
3. Reid JD, Yuh SL, Petrelli M, Jaffe R. Ductuloinsular tumors of the pancreas: A light, electron microscopical and immunohistochemical study. Cancer 1982; 49: 908-915.
4. Kashiwabara K, Nakajima T, Shinkai H et al. A case of malignant duct-islet cell tumor of the pancreas: Immunohistochemical and cytofluorometric study. Acta Pathol. Jpn 1991; 41: 636-641.
5. Nonomura A, Mizukami Y, Matubara F, Kono N, Nakanuma Y. Duct-islet cell tumor of the pancreas. A case report with immunohistochemical and electron microscopic findings. Acta Pathol. Jpn 1989; 39: 328-335.
6. Permert J, Mogaki M, Sandberg AA, Kazakoff K, Pour PM. Pancreatic mixed ductal-islet tumors: Is this an entity? Int. J. Pancreatol. 1992; 11: 23-29.
7. Terada T, Matsunaga Y, Maeta H, Endo K, Horie S, Ohta T. Mixed ductal-endocrine carcinoma of the pancreas presenting as gastrinoma with Zollinger-Ellison syndrome. Virchows Arch. 1999; 435: 606-611.
8. Leteurtre E, Brami F, Kerr-Conte J, Quandalle P, Lecomte-Houcke M. Mixed ductal-endocrine carcinoma of the pancreas. A case study with mixed ductal-endocrine metastasis double labeled for cytokeratin 19 and synaptophysin. Arch. Pathol. Lab. Med. 2000; 124: 284-286.
9. Regitnig P, Spuller E, Denk H. Insulinoma of the pancreas with insular-ductular differentiation in its liver metastasis. Indication of a common stem-cell origin of the exocrine and endocrine components. Virchows Arch. 2001; 438: 624-628.
10. Ulich T, Cheng L, Lewin KJ. Acinar-endocrine cell tumor of the pancreas. Report of a pancreatic tumor containing both zymogen and neuroendocrine granules. Cancer 1982; 50: 2099-2105.
11. Muramatsu T, Kijima H, Tsuchida T et al. Acinar-islet cell tumor of the pancreas. Report of a malignant pancreatic composite tumor. J. Clin. Gastroenterol. 2000; 31: 175-178.
12. Ogawa T, Isaji S, Yatabe T. A case of mixed acinar and endocrine carcinoma of the pancreas discovered in an asymptomatic subject. Int. J. Pancreatol. 2000; 27: 249-257.
13. Klimstra DS, Rosai J, Heffess CS. Mixed acinar-endocrine carcinoma of the pancreas. Am. J. Surg. Pathol. 1994; 18: 765-778.
14. Schron DS, Mendelsohn G. Pancreatic carcinoma with duct, endocrine, and acinar differentiation. A histologic, immunohistochemical, and ultrastructural study. Cancer 1984; 54: 1766-1770.
15. Tanakaya K, Teramoto N, Konaga E et al. Mixed duct-acinar-islet cell tumor of the pancreas. Report of a case. Surg. Today 2001; 31: 177-179.
16. Nonomura A, Kono N, Mizukami Y, Nakanuma Y, Matsubara F. Duct-acinar-islet cell tumor of the pancreas. Ultrastruct. Pathol. 1992; 16: 317-329.
17. Okada Y, Mori H, Tsutsumi A. Duct-acinar-islet cell tumor of the pancreas. Pathol. Int. 1995; 45: 669-676.
18. Eusebi V, Capella C, Bondi A, Sess F, Vezzandini P, Manchini AM. Endocrine-paracrine cells in pancreatic exocrine carcinomas. Histopathology 1981; 5: 599-613.
19. Terada T, Ohta T, Kitamura Y, Ashida K, Matsunaga Y, Kato M. Endocrine cells in intraductal papillary-mucinous neoplasms of the pancreas: A histochemical and immunohistochemical study. Virchows Arch. 1997; 431: 31-36.
20. Kloppel G. Mixed exocrine and endocrine tumors of the pancreas. Semin. Diag. Pathol. 2000; 17: 104-108.
21. Bosman FT. Endocrine cells in non-endocrine tumours. J. Pathol. 1989; 159: 181-182.
22. Terada T, Kitamura Y, Ohta T, Nakanuma Y. Endocrine cells in hepatobiliary cystadenoma and cystadenocarcinoma. Virchows Arch. 1997; 430: 37-40.
23. Asa SL. The endocrine pancreas and its tumor. Rev. Endocrine Pathol. 1993; 4: 120-130.
24. Githens S. Development and differentiation of pancreatic duct epithelium. In: Sirica AE, Longnecker DS, eds. Biliary and Pancreatic Ductal Epithelia: Pathobiology and Pathophysiology. Dekker, New York, 1997; 328-348.
25. Larsson LI. Endocrine pancreatic tumors. Hum. Pathol. 1978; 9: 401-406.
26. Yang YH, Hunter WC. The relation of pancreatic ducts to the islets of Langerhans. Arch. Pathol. 1959; 67: 505-514.
27. Pour PM, Weide L, Liu G et al. Experimental evidence for the origin of duct-type adenocarcinoma from the islets of Langerhans. Am. J. Pathol. 1997; 150: 2167-2180.
28. Yuan S, Rosenberg L, Paraskevas S, Agapitos D, Duguid WP. Transdifferentiation of human islets to pancreatic ductal cells in collagen matrix culture. Differentiation 1996; 61: 67-75.
29. Kerr-Conte J, Pattou F, Zlecomte-Houcke Xia Y, Boilly B, Proye C, Lefebvre J. Ductal cysts formation in collagen-embedded adult human islet preparations. A mean to the nesidioblastosis in vitro. Diabetes 1996; 45: 1108-1114.
30. Pour PM. Islet cells as a component of pancreatic ductal neoplasms. I. Experimental study: Ductular cells, including islet cell precursor, as progenitor cells of tumors. Am. J. Pathol. 1978; 90: 295-316.
31. Pour PM, Althoff J, Takahashi M. Early lesion of pancreatic ductal carcinoma in the hamster model. Am. J. Pathol. 1977; 88: 291-308.
32. Terada T, Ohta T, Kitamura Y, Ashida K, Matsunaga Y. Cell proliferative activity in intraductal papillary mucinous neoplasms and invasive ductal adenocarcinoma of the pancreas: An immunohistochemical study. Arch. Pathol. Lab. Med. 1998; 122: 42-46.
33. Ohike N, Morohoshi T. Immunohistochemical analysis of cyclooxygenase (COX)-2 expression in pancreatic endocrine tumors: Association with tumor progression and proliferation. Pathol. Int. 2001; 51: 770-777.
34. Suh KS, Roh HR, Koh YT, Lee KU, Park YH, Kim SW. Clinicopathologic features of the intraductal growth type of peripheral cholangiocarcinoma. Hepatology 2000; 31: 12-17.
35. Terada T, Kawai K, Nakanuma Y. Small hepatocellular carcinoma presenting as intraductal pedunculated polyp and obstructive jaundice. J. Clin. Gastroenterol. 1988; 414: 53-59.