Zinc metal-promoted cross-coupling reaction of non-activated alkyl halides with aldehydes in the presence of chlorotrimethylsilane

Synlett

Volumn , Issue 12, 2002, Pages 2116-2118

  Ito, Takatoshi ^a   Ishino, Yoshio ^a   Mizuno, Takumi ^a   Ishikawa, Akira ^b   Kobayashi, Jun Ichi ^b  

^a OSAKA MUNICIPAL TECHNICAL RESEARCH INSTITUTE   (Japan)

^b Marubishi Oil Chemical Co Ltd   (Japan)

Author keywords

Addition reactions; Aldehydes; Non activated alkyl halides; TMSCl; Zinc

Indexed keywords

ALCOHOL DERIVATIVE; ALDEHYDE; ALKYL GROUP; CHLOROTRIMETHYLSILANE; HALIDE; REAGENT; TETRAHYDROFURAN; ZINC;

ADDITION REACTION; ARTICLE; REACTION ANALYSIS;

EID: 0036458270     PISSN: 09365214     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2002-35583     Document Type: Article

References (23)

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20. 2O.
21. 3: 236.1412. Found: 236.1390.
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23. In this reaction, the role of TMSC1 may be postulated mainly to be the activation of aldehydes 3 by coordination of the Si atom to the carbonyl group.