Lipopolysaccharide-cell interaction and induced cellular activation in whole blood of septic patients

Journal of Endotoxin Research

Volumn 8, Issue 5, 2002, Pages 371-379

  Salomao, Reinaldo ^a   Brunialti, Milena K C ^a   Kallás, Esper G ^a   Martins, Paulo S ^a   Rigato, Otelo ^a   Freudenberg, Marina ^b  

^a FEDERAL UNIVERSITY OF SÃO PAULO   (Brazil)

^b MAX PLANCK INSTITUTE OF IMMUNOBIOLOGY AND EPIGENETICS   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIUM LIPOPOLYSACCHARIDE; CD69 ANTIGEN; CD8 ANTIGEN; FAS ANTIGEN; HLA DR ANTIGEN; TUMOR NECROSIS FACTOR ALPHA;

ADULT; AGED; ANTIGEN EXPRESSION; BINDING AFFINITY; BIOTINYLATION; CELL ACTIVATION; CELL INTERACTION; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; FLOW CYTOMETRY; HUMAN; INCUBATION TIME; MALE; MONOCYTE; REVIEW; SEPSIS; SIGNAL TRANSDUCTION; T LYMPHOCYTE;

ADOLESCENT; ADULT; ANTIGENS, CD; ANTIGENS, CD95; ANTIGENS, DIFFERENTIATION, T-LYMPHOCYTE; BIOTINYLATION; CASE-CONTROL STUDIES; CD8-POSITIVE T-LYMPHOCYTES; FLOW CYTOMETRY; HLA-DR ANTIGENS; HUMANS; KINETICS; LIPOPOLYSACCHARIDES; LYMPHOCYTE ACTIVATION; MALE; MONOCYTES; SEPSIS; T-LYMPHOCYTES; TUMOR NECROSIS FACTOR-ALPHA;

BACTERIA (MICROORGANISMS);

EID: 0036452725     PISSN: 09680519     EISSN: None     Source Type: Journal    
DOI: 10.1179/096805102125000704     Document Type: Review

References (34)

1. Galanos C, Freudenberg M, Katschinski T, Salomao R, Mossmann H, Kumazawa Y. Tumor necrosis factor and host response to endotoxin. In: Ryan J. (ed) Bacterial Endotoxin Lipopolysaccharides. Boca Raton, FL: CRC Press, 1992; 75-104.
2. Matsuura M, Galanos C. Induction of hypersensitivity to endotoxin and tumor necrosis factor by sublethal infection with Salmonella typhimurium. Infect Immun 1990; 58: 935-937.
3. Bartholeyns J, Freudenberg M, Galanos C. Growing tumors induce hypersensitivity to endotoxin and tumor necrosis factor. Infect Immun 1987; 55: 2230-2233.
4. Galanos C, Freudenberg MA. Mechanisms of endotoxin shock and endotoxin hypersensitivity. Immunobiology 1993; 187: 346-356.
5. Katschinski T, Galanos C, Coumbos A, Freudenberg MA. Gamma interferon mediates Propionibacterium acnes-induced hypersensitivity to lipopolysaccharide in mice. Infect Immun 1992; 60: 1994-2001.
6. Freudenberg M, Merli T, Singer A, Galanos C, Salomao R. Bacteria-induced hypersensitivity to endotoxin. In: Brade H, Vogel S, Morrison DC. (eds) Endotoxin in Health and Disease. New York: Marcel Dekker, 1999; 719-733.
7. Galanos C, Freudenberg MA, Reutter W. Galactosamine-induced sensitization to the lethal effects of endotoxin. Proc Natl Acad Sci USA 1979; 76: 5939-5943.
8. Johnston CA, Greisman SE. Mechanisms of endotoxin tolerance. In: Brade H. (ed) Handbook of Endotoxin. Pathophysiology of Endotoxin, vol 1. Amsterdam: Elsevier, 1985; 359-401.
9. Hailman E, Lichenstein HS, Wurfel MM et al. Lipopolysaccharide (LPS)-binding protein accelerates the binding of LPS to CD14. J Exp Med 1994; 179: 269-277.
10. Schumann RR, Leong SR, Flaggs GW et al. Structure and function of lipopolysaccharide binding protein. Science 1990; 249: 1429-1431.
11. Schlichting E, Aspelin T, Lyberg T. Interactions of endotoxin with human blood cells and serum proteins. Scand J Clin Lab Invest 1996; 56: 167-176.
12. Tobias PS, Mathison JC, Ulevitch RJ. A family of lipopolysaccharide binding proteins involved in responses to Gram-negative sepsis. J Biol Chem 1988; 263: 13479-13481.
13. Heumann D, Gallay P, Betz-Corradin S, Barras C, Baumgartner JD, Glauser MP. Competition between bactericidal/permeability-increasing protein and lipopolysaccharide-binding protein for lipopolysaccharide binding to monocytes. J Infect Dis 1993; 167: 1351-1357.
14. Salomao R, Rigato O, Pignatari AC, Freudenberg MA, Galanos C. Bloodstream infections: epidemiology, pathophysiology and therapeutic perspectives. Infection 1999; 27: 1-11.
15. von der Mohlen MA, van der Poll T, Jansen J, Levi M, van Deventer SJ. Release of bactericidal/permeability-increasing protein in experimental endotoxemia and clinical sepsis. Role of tumor necrosis factor. J Immunol 1996; 156: 4969-4973.
16. Opal SM, Scannon PJ, Vincent JL et al. Relationship between plasma levels of lipopolysaccharide (LPS) and LPS-binding protein in patients with severe sepsis and septic shock. J Infect Dis 1999; 180: 1584-1589.
17. Ertel W, Kremer JP, Kenney J et al. Downregulation of proinflammatory cytokine release in whole blood from septic patients. Blood 1995; 85: 1341-1347.
18. Mitov IG, Kropec A, Benzing A et al. Differential cytokine production in stimulated blood cultures from intensive care patients with bacterial infections. Infection 1997; 25: 206-212.
19. Abbas AK, Lichtman AH, Pober JS. Regulation of immune responses. In: Abbas AK, Pober JS. (eds) Cellular and Molecular Immunology, 3rd edn. Philadelphia, PS: Saunders, 1997; 213-230.
20. American College of Chest Physicians/Society of Critical Care Medicine Consensus Conference Committee. Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis. Crit Care Med 1992; 20: 864-874.
21. Galanos C, Lüderitz O, Rietschel ET, Westphal O. Newer aspects of the chemistry and biology of bacterial lipopolysaccharides, with special reference to their lipid A component. Int Rev Biochem 1977; 14: 239-335.
22. Brunialti MK, Kallas EG, Freudenberg M, Galanos C, Salomao R. Influence of EDTA and heparin on lipopolysaccharide binding and cell activation, evaluated at single-cell level in whole blood. Cytometry 2002; 50: 14-18.
23. Diament D, Brunialti MK, Romero EC, Kallas EG, Salomao R. Peripheral blood mononuclear cell activation induced by Leptospira interrogans glycolipoprotein. Infect Immun 2002; 70: 1677-1683.
24. Kitchens RL, Thompson PA, Viriyakosol S, O'Keefe GE, Munford RS. Plasma CD14 decreases monocyte responses to LPS by transferring cell-bound LPS to plasma lipoproteins. J Clin Invest 2001; 108: 485-493.
25. Papathanassoglou ED, Moynihan JA, McDermott MP, Ackerman MH. Expression of Fas (CD95) and Fas ligand on peripheral blood mononuclear cells in critical illness and association with multiorgan dysfunction severity and survival. Crit Care Med 2001; 29: 709-718.
26. Schroeder S, Lindemann C, Decker D et al. Increased susceptibility to apoptosis in circulating lymphocytes of critically ill patients. Langenbecks Arch Surg 2001; 386: 42-46.
27. + expression in sepsis. Clin Microbiol Infect 2000; 6: 657-660.
28. + T lymphocytes in humans. J Immunol 2001; 166: 6952-6963.
29. Docke WD, Randow F, Syrbe U et al. Monocyte deactivation in septic patients: restoration by IFN-gamma treatment. Nat Med 1997; 3: 678-681.
30. Zweigner J, Gramm HJ, Singer OC, Wegscheider K, Schumann RR. High concentrations of lipopolysaccharide-binding protein in serum of patients with severe sepsis or septic shock inhibit the lipopolysaccharide response in human monocytes. Blood 2001; 98: 3800-3808.
31. Ziegler-Heitbrock HW. Molecular mechanism in tolerance to lipopolysaccharide. J Inflamm 1995; 45: 13-26.
32. Ziegler-Heitbrock HW, Wedel A, Schraut W et al. Tolerance to lipopolysaccharide involves mobilization of nuclear factor kappa B with predominance of p50 homodimers. J Biol Chem 1994; 269: 17001-17004.
33. Nomura F, Akashi S, Sakao Y et al. Cutting edge: endotoxin tolerance in mouse peritoneal macrophages correlates with down-regulation of surface Toll-like receptor 4 expression. J Immunol 2000; 164: 3476-3479.
34. Rigato O, Silva E, Kallás EG, Brunialti MKC, Martins PS, Salomao R. Pathogenic aspects of sepsis and possible targets for adjunctive therapy. Curr Drug Targets 2001; 1: 13-30.